FOXG1 (NM_005249) Human Untagged Clone

CAT#: SC116871

FOXG1 (untagged)-Human forkhead box G1 (FOXG1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FOXG1
• Synonyms: BF1; BF2; FHKL3; FKH2; FKHL1; FKHL2; FKHL3; FKHL4; FOXG1A; FOXG1B; FOXG1C; HBF-1; HBF-2; HBF-3; HBF-G2; HBF2; HFK1; HFK2; HFK3; KHL2; QIN
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_005249, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCTGGACATGGGAGATAGGAAAGAGGTGAAAATGATCCCCAAGTCCTCGTTCAGCATCAACAGCCTGG
  TGCCCGAGGCGGTCCAGAACGACAACCACCACGCGAGCCACGGCCACCACAACAGCCACCACCCCCAGCA
  CCACCACCACCACCACCACCATCACCACCACCCGCCGCCGCCCGCCCCGCAACCGCCGCCGCCGCCGCAG
  CAGCAGCAGCCGCCGCCGCCGCCGCCCCCGGCACCGCAGCCCCCCCAGACGCGGGGCGCCCCGGCCGCCG
  ACGACGACAAGGGCCCCCAGCAGCTGCTGCTCCCGCCGCCGCCACCGCCACCACCGGCCGCCGCCCTGGA
  CGGGGCTAAAGCGGACGGGCTGGGCGGCAAGGGCGAGCCGGGCGGCGGGCCGGGGGAGCTGGCGCCCGTC
  GGGCCGGACGAGAAGGAGAAGGGCGCCGGCGCCGGGGGGGAGGAGAAGAAGGGGGCGGGCGAGGGCGGCA
  AGGACGGGGAGGGGGGCAAGGAGGGCGAGAAGAAGAACGGCAAGTACGAGAAGCCGCCGTTCAGCTACAA
  CGCGCTCATCATGATGGCCATCCGGCAGAGCCCCGAGAAGCGGCTCACGCTCAACGGCATCTACGAGTTC
  ATCATGAAGAACTTCCCTTACTACCGCGAGAACAAGCAGGGCTGGCAGAACTCCATCCGCCACAATCTGT
  CCCTCAACAAGTGCTTCGTGAAGGTGCCGCGCCACTACGACGACCCGGGCAAGGGCAACTACTGGATGCT
  GGACCCGTCGAGCGACGACGTGTTCATCGGCGGCACCACGGGCAAGCTGCGGCGCCGCTCCACCACCTCG
  CGGGCCAAGCTGGCCTTCAAGCGCGGTGCGCGCCTCACCTCCACCGGCCTCACCTTCATGGACCGCGCCG
  GCTCCCTCTACTGGCCCATGTCGCCCTTCCTGTCCCTGCACCACCCCCGCGCCAGCAGCACTTTGAGTTA
  CAACGGCACCACGTCGGCCTACCCCAGCCACCCCATGCCCTACAGCTCCGTGTTGACTCAGAACTCGCTG
  GGCAACAACCACTCCTTCTCCACCGCCAACGGCCTGAGCGTGGACCGGCTGGTCAACGGGGAGATCCCGT
  ACGCCACGCACCACCTCACGGCCGCCGCGCTAGCCGCCTCGGTGCCCTGCGGCCTGTCGGTGCCCTGCTC
  TGGGACCTACTCCCTCAACCCCTGCTCCGTCAACCTGCTCGCGGGCCAGACCAGTTACTTTTTCCCCCAC
  GTCCCGCACCCGTCAATGACTTCGCAGAGCAGCACGTCCATGAGCGCCAGGGCCGCGTCCTCCTCCACGT
  CGCCGCAGGCCCCCTCGACCCTGCCCTGTGAGTCTTTAAGACCCTCTTTGCCAAGTTTTACGACGGGACT
  GTCTGGGGGACTGTCTGATTATTTCACACATCAAAATCAGGGGTCTTCTTCCAACCCTTTAATACATTAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005249 unedited
  TCACCATTTGTATACGACTCACTATAGGCGGCCGCGNAATTCGCACGAGGTACAGTTGGG
  AGCGAGGGAGCTTCACCCCCGGGGCGGTGGTTGTTTCTTTTTTCTTTCTTTCTTTTTTCT
  TTTCCTTTTTTTTTTTTTTTCTAATTCCTGAGGGGTGGTTGCTGCTTTTGCTACATGACT
  TGCCAGCGCCCGAGCCTGCGGTCCAACTGCGCTGCTGCCGGAGCGCTCAGTGCCGCCGCT
  GCCGCCCGCGCCCCCCGCGCCCCGTTCGGCACCCACCGGTCGCCGCCGCCCGCCGCGCCG
  CTGTCCCGCTCCCGCGCCGCCGCCGCCGTTTCCCCCCGACGACTGGGTGATGCTGGACAT
  GGGAGATAGGAAAGAGGTGAAAATGATCCCCAAGTCCTCGTTCAGCATCAACAGCCTGGT
  GCCCGAGGCGGTCCAGAACGACAACCACCACGCGAGCCACGGCCACCACAACAGCCACCA
  CCCCCAGCACCACCACCACCACCACCACCATTACCACCACCCGCCGCCGCCCGCCCCGCA
  ACCGCCGCCGCCGCCGCAGCAGCAGCAGCCGCCGCCGCCGCCGCCCCCGGCACCGCAGCC
  CCCCCAGACGCGGGGCGCCCCGGCCGCCGACGACGACAAGGGCCCCCAGCAGCTGCTGCT
  CCCGCCGCCGNCACCGNCACCACCGGCCGNCGCCCTGGACGGGGCTAAAGNCGACGGGCT
  GGGCGGCAAGGGCGAGCCGGGCGGCGGGCCGGGGGGAGCTGGCGCCCCGTCGGCCGGACG
  AGAAGGAAAGGCGCCGGCGCCCGGGGGGAGGAAAAAAGGGGGCGGGCNAGGCGNNNAAGA
  CGGGGAAGGGGGCAAGGAGGCCCAAAAAAAACCGCAGTTCCAAAAACCCCGNTCAATTCA
  ACCGCTAATATGATGGCCATCGGCAAACCCCAAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_005249 unedited
  NCCGTTGCGGGGATAGTTTGTGTGTGTGGATGGAAACGTTTTGTAGGGACGTACCGGGCA
  TATGACCACGAGGTCACAGTCAGGAAATTTTAAGACAACATTAACAATGACTCAAATTTA
  TGCGGCATTTGCGCAACACAGGTTACATATTTGCAAGGTTTACCTATAAGTACAATAGGT
  ATTAACATTTCACTACATTTAGAAAAAATAAAAGTGACCTGTTAGTGACCACATACATCA
  AAATATACACAACACAAACTGAAGGCAATCGTTAATTTTGTCCCCTTCTGATTCAATTGA
  ATGGGCAGTGTTGCCAACTGAAACAACTTTCCTTTTTGTTTGTTTTAATACTTAGTATAC
  CAAGTGCATTTTCTAGAACCCAATCTTTGGTCTAAAAGTAAACAAAAGAAAAAAAAACAG
  TTCTTTAAAGAAAAGGACAAAACAATAAATGGCCAAAATAATTTCTTGGGCACCTTTACT
  ACGAATGCTTTTTAAATACAAATTACAGTTTAACATTTTAAAATTCTCCCCATAATTTAG
  GTTGTTCTCAAGGTCTGCGTCCACCATATAGTTCCATGATAACTTATAATACTGCACACA
  TGGAAATCTGGCGGCTCTTAGAGATAGACTTGTCAGGTTTGAATGAAATGGCAAAGCAGT
  CACTATTTAGATACACATTCTACTATAATTTGACTTCCAAACCTTATATTCTACAATGTA
  TTCTCCCCACATTGCACCTCGCTGACACTTCACACCTTGNTAGAATAATAAACAACCCTA
  GAGACTGGACAAACGTACAGGAATGGGAAGGGGGGGCCTAAATAAAAAATAACCTGGACT
  TATTTTTTTAATTATCATTTAACATGCAAATGTGTGTAAACGTTTACTTTACAGCTTGTT
  CCCAGGTATGTTAATGTATTAAAGGGTTGAAAN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_005249
• Insert Size: 2940 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_005249.3, NP_005240.3
• RefSeq Size: 2600 bp
• RefSeq ORF: 1470 bp
• Locus ID: 2290
• UniProt ID: P55316
• Cytogenetics: 14q12
• Domains: FH
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: This locus encodes a member of the fork-head transcription factor family. The encoded protein, which functions as a transcriptional repressor, is highly expressed in neural tissues during brain development. Mutations at this locus have been associated with Rett syndrome and a diverse spectrum of neurodevelopmental disorders defined as part of the FOXG1 syndrome. This gene is disregulated in many types of cancer and is the target of multiple microRNAs that regulate the proliferation of tumor cells. [provided by RefSeq, Jul 2020]