PQBP1 (NM_005710) Human Untagged Clone

SKU SC116572

PQBP1 (untagged)-Human polyglutamine binding protein 1 (PQBP1), transcript variant 1

Product Data

• Type: Human Untagged Clone
• Target Symbol: PQBP1
• Synonyms: MRX2; MRX55; MRXS3; MRXS8; NPW38; RENS1; SHS
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_005710, the custom clone sequence may differ by one or more nucleotides; ; ; ATGCCGCTGCCCGTTGCGCTGCAGACCCGCTTGGCCAAGAGAGGCATCCTCAAACATCTGGAGCCTGAAC; CAGAGGAAGAGATCATTGCCGAGGACTATGACGATGATCCTGTGGACTACGAGGCCACCAGGTTGGAGGG; CCTACCACCAAGCTGGTACAAGGTGTTCGACCCTTCCTGCGGGCTCCCTTACTACTGGAATGCAGACACA; GACCTTGTATCCTGGCTCTCCCCACATGACCCCAACTCCGTGGTTACCAAATCGGCCAAGAAGCTCAGAA; GCAGTAATGCAGATGCTGAAGAAAAGTTGGACCGGAGCCATGACAAGTCGGACAGGGGCCATGACAAGTC; GGACCGCAGCCATGAGAAACTAGACAGGGGCCACGACAAGTCAGACCGGGGCCACGACAAGTCTGACAGG; GATCGAGAGCGTGGCTATGACAAGGTAGACAGAGAGAGAGAGCGAGACAGGGAACGGGATCGGGACCGCG; GGTATGACAAGGCAGACCGGGAAGAGGGCAAAGAACGGCGCCACCATCGCCGGGAGGAGCTGGCTCCCTA; TCCCAAGAGCAAGAAGGCAGTAAGCCGAAAGGATGAAGAGTTAGACCCCATGGACCCTAGCTCATACTCA; GACGCCCCCCGGGGCACGTGGTCAACAGGACTCCCCAAGCGGAATGAGGCCAAGACTGGCGCTGACACCA; CAGCAGCTGGGCCCCTCTTCCAGCAGCGGCCGTATCCATCCCCAGGGGCTGTGCTCCGGGCCAATGCAGA; GGCCTCCCGAACCAAGCAGCAGGATTGA; ;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005710 unedited; ACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGGCTCGGGGAGTGAAGGCCTCG; TTGAGAGAAGGTCTCATTCGGTGTTTTGGGAAGAGAGTCGTGTGGGCCCAGGTCTGTCTG; CTATCAGCTATGCCGCTGCCCGTTGCGCTGCAGACCCGCTTGGCCAAGAGAGGCATCCTC; AAACATCTGGAGCCTGAACCAGAGGAAGAGATCATTGCCGAGGACTATGACGATGATCCT; GTGGACTACGAGGCCACCAGGTTGGAGGGCCTACCACCAAGCTGGTACAAGGTGTTCGAC; CCTTCCTGCGGGCTCCCTTACTACTGGAATGCAGACACAGACCTTGTATCCTGGCTCTCC; CCACATGACCCCAACTCCGTGGTTACCAAATCGGCCAAGAAGCTCAGAAGCAGTAATGCA; GATGCTGAAGAAAAGTTGGACCGGAGCCATGACAAGTCGGACAGGGGCCATGACAAGTCG; GACCGCAGCCATGAGAAACTAGACAGGGGCCACGACAAGTCAGACCGGNGCCACGACAAG; TCTGACAGGGATCGAGAGCGTGGCTATGACAAGGTAGACAGAGAGAGAGAGCGAGACAGG; GAACGGGATCGGGACCGCGGGTATGACAAGGCAGACCGGGAAGAGGGCAAAGATCGGCGC; CACCATCGCCGGGAGGAGCTGGCNTCCTATCCCAAGAGTCAGATAGGCAGTAGCCCGAAT; NATGAAGAGTTAGACCCCATGGACCCTAGCTCATACTCAGAACGCCCCCGGNGCACGTGG; TCAACAGGACTCCCCCAGCGGTATGATGCCCAGACTGCCGCTGACACACAGCAGCTGGGC; CCCTCTTCAGCAGCGGCCGTATCCATCCCAGGGGCTGTGCTCCCGGCCATGCANATGCCC; TCCGACCAGCAGNAGGATGAACCTCGCCTCCTGGCCTGGGTAAATAAAGCTCCTGGGATC; TGCCACAAAAAAAAAAACTCGCTCTAATGCGCGGTCTACTG;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_005710 unedited; TATGAACCGCGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTGTGGGCAGGATCA; CCAGAAAGCTTTTATTTTAACCCAGGGCCAGGGAGGCCGAAGCTTCAATCCTGCTGCTTG; GTTCGGGAGGCCTCTGCATTGGCCCGGAGCACAGCCCCTGGGGATGGATACGGCCGCTGC; TGGAAGAGGGGCCCAGCTGCTGTGGTGTCAGCGCCAGTCTTGGCCTCATTCCGCTTGGGG; AGTCCTGTTGACCACGTGCCCCGGGGGGCGTCTGAGTATGAGCTAGGGTCCATGGGGTCT; AACTCTTCATCCTTTCGGCTTACTGCCTTCTTGCTCTTGGGATAGGGAGCCAGCTCCTCC; CGGCGATGGTGGCGCCGTTCTTTGCCCTCTTCCCGGTCTGCCTTGTCATACCCGCGGTCC; CGATCCCGTTCCCTGTCTCGCTCTCTCTCTCTGTCTACCTTGTCATAGCCACGCTCTCGA; TCCCTGTCAGACTTGTCGTGGCCCCGGTCTGACTTGTCGTGGCCCCTGTCTAGTTTCTCA; TGGCTGCGGTCCGACTTGTCATGGCCCCTGTCCGACTTGTCATGGCTCCGGTCCAACTTT; TCTTCAGCATCTGCATTACTGCTTCTGAGCTTCTTGGCCGATTTGGTAACCACGGAGTTG; GGGTCATGTGGGGAGAGCCAGGATACAAGGTCTGTGTCTGCATTCCAGTAGTAAGGGAGC; CCGCANGAAGGGTCGAACACCTTGTACCAGCTTGGTGGTAGGCCCTCCAACCTGGTGGCC; TCGTAGTCCACAGGATCATCGTCATAGTCCTCGGCAATGATCTCTTCCTCTGGTTCAGGC; TCCAGATGTCTGAGGATGCCTCTCTTGGGCAAGCGGTTCTGCAGCGCAACCGGGCAGCGG; CATAACTGATAACAGACAGACCTGGGCCCACCNACTCTCCTTCCCAAACACCGAATGAGA; CCTTCTCTCACGAGCCCTTACTCCCGGAGCCCT;
• Restriction Sites: NotI-NotI
• ACCN: NM_005710
• Insert Size: 900 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_005710.2, NP_005701.1
• RefSeq Size: 1147 bp
• RefSeq ORF: 798 bp
• Locus ID: 10084
• UniProt ID: O60828
• Cytogenetics: Xp11.23
• Domains: WW
• Protein Families: Transcription Factors
• Protein Pathways: Spliceosome
• Summary: This gene encodes a nuclear polyglutamine-binding protein that is involved with transcription activation. The encoded protein contains a WW domain. Mutations in this gene have been found in patients with Renpenning syndrome 1 and other syndromes with X-linked cognitive disability. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.[provided by RefSeq, Nov 2009]; Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Variants 1, 2, 3, 4, and 5 all encode the same protein (isoform 1).