GM CSF Receptor alpha (CSF2RA) (NM_006140) Human Untagged Clone

SKU SC116268

CSF2RA (untagged)-Human colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) (CSF2RA), transcript variant 1

Product Data

• Type: Human Untagged Clone
• Target Symbol: GM CSF Receptor alpha
• Synonyms: alphaGMR; CD116; CDw116; CSF2R; CSF2RAX; CSF2RAY; CSF2RX; CSF2RY; GM-CSF-R-alpha; GMCSFR; GMCSFR-alpha; GMR; GMR-alpha; SMDP4
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC116268 sequence for NM_006140 edited (data generated by NextGen Sequencing); ATGCTTCTCCTGGTGACAAGCCTTCTGCTCTGTGAGTTACCACACCCAGCATTCCTCCTG; ATCCCAGAGAAATCGGATCTGCGAACAGTGGCACCAGCCTCTAGTCTCAATGTGAGGTTT; GACTCCAGGACGATGAATTTAAGCTGGGACTGCCAAGAAAACACAACCTTCAGCAAGTGT; TTCTTAACTGACAAGAAGAACAGAGTCGTGGAACCCAGGCTCAGTAACAACGAATGTTCG; TGCACATTTCGTGAAATTTGTCTGCATGAAGGAGTCACATTTGAGGTTCACGTGAATACT; AGTCAAAGAGGATTTCAACAGAAACTGCTTTATCCAAATTCAGGAAGGGAGGGTACCGCT; GCTCAGAATTTCTCCTGTTTCATCTACAATGCGGATTTAATGAACTGTACCTGGGCGAGG; GGTCCGACGGCCCCCCGTGACGTCCAGTATTTTTTGTACATACGAAACTCAAAGAGAAGG; AGGGAGATCCGGTGTCCTTATTACATACAAGACTCAGGAACCCATGTGGGATGTCACCTG; GATAACCTGTCAGGATTAACGTCTCGCAATTACTTTCTGGTTAACGGAACCAGCCGAGAA; ATTGGCATCCAATTCTTTGATTCACTTTTGGACACAAAGAAAATAGAACGATTCAACCCT; CCCAGCAATGTCACCGTACGTTGCAACACGACGCACTGCCTCGTACGGTGGAAACAGCCC; AGGACCTATCAGAAGCTGTCGTACCTGGACTTTCAGTACCAGCTGGACGTCCACAGAAAG; AATACCCAGCCTGGCACGGAAAACCTACTGATTAATGTTTCTGGTGATTTGGAAAATAGA; TACAACTTTCCAAGCTCTGAGCCCAGAGCAAAACACAGTGTGAAGATCAGAGCTGCAGAC; GTCCGCATCTTGAATTGGAGCTCCTGGAGTGAAGCCATTGAATTTGGTTCTGACGACGGG; AACCTCGGCTCTGTGTACATTTATGTGCTCCTAATCGTGGGAACCCTTGTCTGTGGCATC; GTCCTCGGCTTCCTCTTTAAAAGGTTCCTTAGGATACAGCGGCTGTTCCCGCCAGTTCCA; CAGATCAAAGACAAACTGAATGATAACCATGAGGTGGAAGACGAGATCATCTGGGAGGAA; TTCACCCCAGAGGAAGGGAAAGGCTACCGCGAAGAGGTCTTGACCGTGAAGGAAATTACC; TGA; ; Clone variation with respect to NM_006140.4;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006140 unedited; GTCAGGATATGTAAACGACTTACTATAGGGCGGCCGCGCAATTCGCACGAGGAAAAGCGG; TGGAAGGAGAGGAAGCGGATGCCGTGGGGTTTACAGCAGGGAAAATCCGTGGAGACAGCA; GATCCGAGAAGCGGCGATGTTTGCGTAGAACCCTGTACGTGCTTCCTTCGGCCTGTCGCT; CTTCCCTTCTCTCTGACCAGCACCATGCTTCTCCTGGTGACAAGCCTTCTGCTCTGTGAG; TTACCACACCCAGCATTCCTCCTGATCCCAGAGAAATCGGATCTGCGAACAGTGGCACCA; GCCTCTAGTCTCAATGTGAGGTTTGACTCCAGGACGATGAATTTAAGCTGGGACTGCCAA; GAAAACACAACCTTCAGCAAGTGTTTCTTAACTGACAAGAAGAACAGAGTCGTGGAACCC; AGGCTCAGTAACAACGAATGTTCGTGCACATTTCGTGAAATTTGTCTGCATGAAGGAGTC; ACATTTGAGGTTCACGTGAATACTAGTCAAAGAGGATTTCAACAGAAACTGCTTTATCCA; AATTCAGGAAGGGAGGGTACCGCTGCTCAGAATTTCTCCTGTTTCATCTACAATGCGGAT; TTAATGAACTGTACCTGNGCGAAGGGTCCGACGGCCCCCCGTGACGTCCAGTATTTTTTG; TACATACGAAACTCAAAGAGAAGGAAGGAGATCCCGTGTCCTTATTACATACAAGACTCA; NGAACCCATGTGGGATGTCACCTGGATAACCTGTCCAGATTAACGTCTCGCAATTACTTT; CTGGTTAAGGAACCAGCCGAGAAATGGCATCCAATTCTTTGATTCACTTTCGGCACAAAG; AAAATGAACGATTCACCCTCCCAGCATGTCACCGTACGTTGAACACCACGCCTGCCCGTA; CGGTGAAACAGCCCAGA;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006140 unedited; TAGAGTCGAGNNNTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT; TTTTTCCCCACCCAAATATCAGGGGTTTAATAATTAATAATAATGGGGGGTTTGGAAAAG; CAATTTTGCTTTGTCACCCAGGTTGGGGGGCAATGGGGCAATTTTGGTTAACTACAACCT; CCGCCTAAGGGGTTAAAGCAATTTTCCTGCCTCACCCTCCCAAGTACCTGGGATGATGGG; CGTCCCCCCCCGGGCCTGGGAAAATTTCTGCATTTTTAGCCCAAAGGGGGTTTCACCATG; TGGGGCAGGCTGGTCTTGAACTCCTGACCTAAGGGGATCCCCCTGCCTTGGCCTCCCAAA; GGGCTGGGATTACAGGCGTGACCCACCGCCCCTGGCCCCAAATGTCATGTTTTTAAATAA; AACCTTAAAAAATGATTTAAGGGTTCCCAGCTTCTTCAAAAAAACAGTTCCTCCGTGTCC; CGGAGGCGGAAATGTCCATGCCATTCCTACACCCTTTGGGTCTCAGGTAATTTCCTTCAC; GGACAAGACCTCTTCGGGGAACCCTTTCCCTTCCTGTGGGGTGAATTCCTCCCAAAGATC; CCGTCTTCCCCTCAGGGTTATATTCANTTTGCCTTGATCTGGGAACTGGCGGAACACCCG; CTGATCCTAAGAACCTTTAAAGAGGAACCCAGGACCATCCCCCAAAAGGGTTCCCACATT; AGACCCATAATGTCACAAACCCGGGTTCCCGTTGTAAACCCAATTAAGGTTTACTCCAGG; ACCCCATTTAAGAGCGGCCGTTGCATTTTGATCTCACATTGGTTTTGCTCGGGCTAAAAC; TTGAAATTTTTTCTTTTCCAACACAAAAACATTATAAAGGTTCCCGGCCCCTTGGATTTT; TTTGGGCCTCCCTTGTCCTGAACAGAACCAAATCTTTATGGCTGGCGTGTCCCCCAAAGG; AGGCGTTGGTTCACAAGGGAA;
• Restriction Sites: NotI-NotI
• ACCN: NM_006140
• Insert Size: 1910 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_006140.3, NP_006131.2
• RefSeq Size: 1844 bp
• RefSeq ORF: 1203 bp
• Locus ID: 1438
• UniProt ID: P15509
• Cytogenetics: X;Y
• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway, Pathways in cancer
• Summary: The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. This gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. Multiple transcript variants encoding different isoforms have been found for this gene, with some of the isoforms being membrane-bound and others being soluble. [provided by RefSeq, Jul 2008]; Transcript Variant: This variant (1) and variants 2 and 7 encode the same isoform (a), which is membrane-bound.