Peroxiredoxin 4 (PRDX4) (NM_006406) Human Untagged Clone

CAT#: SC116095

PRDX4 (untagged)-Human peroxiredoxin 4 (PRDX4)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: Peroxiredoxin 4
• Synonyms: AOE37-2; AOE372; HEL-S-97n; PRX-4
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC116095 sequence for NM_006406 edited (data generated by NextGen Sequencing)
  ATGGAGGCGCTGCCGCTGCTAGCCGCGACAACTCCGGACCACGGCCGCCACCGAAGGCTG
  CTTCTGCTGCCGCTACTGCTGTTCCTGCTGCCGGCTGGAGCTGTGCAGGGCTGGGAGACA
  GAGGAGAGGCCCCGGACTCGCGAAGAGGAGTGCCACTTCTACGCGGGTGGACAAGTGTAC
  CCGGGAGAGGCATCCCGGGTATCGGTCGCCGACCACTCCCTGCACCTAAGCAAAGCGAAG
  ATTTCCAAGCCAGCGCCCTACTGGGAAGGAACAGCTGTGATCGATGGAGAATTTAAGGAG
  CTGAAGTTAACTGATTATCGTGGGAAATACTTGGTTTTCTTCTTCTACCCACTTGATTTC
  ACATTTGTGTGTCCAACTGAAATTATCGCTTTTGGCGACAGACTTGAAGAATTCAGATCT
  ATAAATACTGAAGTGGTAGCATGCTCTGTTGATTCACAGTTTACCCATTTGGCCTGGATT
  AATACCCCTCGAAGACAAGGAGGACTTGGGCCAATAAGGATTCCACTTCTTTCAGATTTG
  ACCCATCAGATCTCAAAGGACTATGGTGTATACCTAGAGGACTCAGGCCACACTCTTAGA
  GGTCTCTTCATTATTGATGACAAAGGAATCCTAAGACAAATTACTCTGAATGATCTTCCT
  GTGGGTAGATCAGTGGATGAGACACTACGTTTGGTTCAAGCATTCCAGTACACTGACAAA
  CACGGAGAAGTCTGCCCTGCTGGCTGGAAACCTGGTAGTGAAACAATAATCCCAGATCCA
  GCTGGAAAGCTGAAGTATTTCGATAAACTGAATTGA
  
  Clone variation with respect to NM_006406.1
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006406 unedited
  NGGGTCACAATTGTAAACGACTCATATAGGCGGCCGCGAATTCGCACGACAAAACGGCGC
  TCGCGCCAAGGACGTGTTTCTGCGCTCGCGTGGTCATGGAGGCGCTGCCGCTGCTAGCCG
  CGACAACTCCGGACCACGGCCGCCACCGAAGGCTGCTTCTGCTGCCGCTACTGCTGTTCC
  TGCTGCCGGCTGGAGCTGTGCAGGGCTGGGAGACAGAGGAGAGGCCCCGGACTCGCGAAG
  AGGAGTGCCACTTCTACGCGGGTGGACAAGTGTACCCGGGAGAGGCATCCCGGGTATCGG
  TCGCCGACCACTCCCTGCACCTAAGCAAAGCGAAGATTTCCAAGCCAGCGCCCTACTGGG
  AAGGAACAGCTGTGATCGATGGAGAATTTAAGGAGCTGAAGTTAACTGATTATCGTGGGA
  AATACTTGGTTTTCTTCTTCTACCCACTTGATTTCACATTTGTGTGTCCAACTGAAATTA
  TCGCTTTTGGCGACAGACTTGAAGAATTCAGATCTATAAATACTGAAGTGGTAGCATGCT
  CTGTTGATTCACAGTTTACCCATTTGGCCTGNATTAATACCCCTCGAAGACAAGGAGGAC
  TTGNGCCAATAAGGATTCCACTTCTTTCAGATTTGACCCATCAGATCTCANAGGACTATG
  GTGTATACCTAGAGGACTCANGCCACACTCTTAGAGGTCTCTTCATTATTGATGACANAG
  GAATCCTAAGACAAATTACTCTGAATGATCTTCCTGTGGGTAGATCAGTGGATGAGACAC
  TACGTTTGGTTCAAGCATTCCAGTACACTGACCAACACGGAGAAGTCTGCCCTGCTGGCT
  GGAAACCTGNTAGNNTGAACATAATCCCAGATCCAGCTGGAAAGCTGAAGTANTTNCGAT
  AACTGAATTGAGAAAACTCNCTCAAGTATGATGCCTNGAAGT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006406 unedited
  GGAGCGCTACGAGGTACCTCGCCGCCCTCAATGATCGGTTTTTTTTTTTTTTTTTTTTTT
  TTTTTTTTTTTTTTTTTGGGAAAGGAAACCCGGAACTTTATTGAGAACTTTCAAACCTCA
  TAACTTGAAAAAATATTTCTCAATTCAGTTTATCGAAATACTTCAGCTTTCCAGCTGGAT
  CTGGGATTATTGGTTCACTACCAGGTTTCCAGCCCGCAGGGCAAACTTCTCCCTGTTTGT
  CAATGGACTGGAATGCCTGAACCAAACGTAGTGGCTCATCCACTGGTCTACCCACAGGAA
  GATCATTCAGAGTAATTTGTCTTAAGATTCCCTTGGCATCAATAATGAAAAAACCCCTAA
  AAATGGGGCCCGAGTCCCCTAGGGATACCCCATAATCCTTTGAGATCCGATGGGGCAAAT
  CTGAAAGAAGTGGAATCCCTATTGGCCCAAGTCCTCCTTGGCTTCGAGGGGGATTAATCC
  CGGCCCAATGGGGAAACCGGGAATCAACAGAACATGCTACCACTTCAGTATTTATAGATC
  TGAATTCTTCAAGTCTGGCGCCCAAAGCGATAATTTCAGTTGGACACACAAATGTGAAAT
  CAAGTGGGTAGAAAAAGAAAACCAAGTATTTCCCACGATAATCAGTTAACTTCAGCTCCT
  TAAATTCTCCATCGATCACAGCTGTTCCCTCCCAATAAGGCGCTGGCTTGAAAATCTTCC
  CTTTGCTTAAGTGCAGGAAGTGTTCGGCGACCGATACCCGGGGAGCCTCTCCCGGGTACA
  CTTGTCCACCGCCGTAAAATGGCCCTCCTCTCGCGAGTTCGGGGCCCCTCCTCTGTCTCC
  C
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006406
• Insert Size: 900 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_006406.1, NP_006397.1
• RefSeq Size: 921 bp
• RefSeq ORF: 816 bp
• Locus ID: 10549
• UniProt ID: Q13162
• Cytogenetics: Xp22.11
• Domains: AhpC-TSA
• Protein Families: Druggable Genome
• Gene Summary: The protein encoded by this gene is an antioxidant enzyme and belongs to the peroxiredoxin family. The protein is localized to the cytoplasm. Peroxidases of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappaB. [provided by RefSeq, Jul 2008]