p23 (PTGES3) (NM_006601) Human Untagged Clone

CAT#: SC115976

PTGES3 (untagged)-Human prostaglandin E synthase 3 (cytosolic) (PTGES3)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: p23
• Synonyms: cPGES; P23; TEBP
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC115976 sequence for NM_006601 edited (data generated by NextGen Sequencing)
  ATGCAGCCTGCTTCTGCAAAGTGGTACGATCGAAGGGACTATGTCTTCATTGAATTTTGT
  GTTGAAGACAGTAAGGATGTTAATGTAAATTTTGAAAAATCCAAACTTACATTCAGTTGT
  CTCGGAGGAAGTGATAATTTTAAGCATTTAAATGAAATTGATCTTTTTCACTGTATTGAT
  CCAAATGATTCCAAGCATAAAAGAACGGACAGATCAATTTTATGTTGTTTACGAAAAGGA
  GAATCTGGCCAGTCATGGCCAAGGTTAACAAAAGAAAGGGCAAAGCTTAATTGGCTTAGT
  GTCGACTTCAATAATTGGAAAGACTGGGAAGATGATTCAGATGAAGACATGTCTAATTTT
  GATCGTTTCTCTGAGATGATGAACAACATGGGTGGTGATGAGGATGTAGATTTACCAGAA
  GTAGATGGAGCAGATGATGATTCACAAGACAGTGATGATGAAAAAATGCCAGATCTGGAG
  TAA
  
  Clone variation with respect to NM_006601.5
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006601 unedited
  GCGGACGCGCAATTCGCACGAGGCCTCGTGCCGAATTCGGCACGAGGGCTCTTTCCGCGC
  GGTGCATTCTGGGGCCCGAGGTCGAGCCCGCCGCTGCCGCCGTCGCCTGAGGGAAGCGAG
  AAGAGGCCGCGACCGGAGAGAAAAAGCGGAGTCGCCACCGGAGAGAAGTCGACTCCCTAT
  CTTCAGCCGCCGCCAGAGAGGCCCGCCCACCAGTTCGCCCGTCCCCCTGCCCCGTTCACA
  ATGCAGCCTGCTTCTGCAAAGTGGTACGATCGAAGGGACTATGTCTTCATTGAATTTTGT
  GTTGAAGACAGTAAGGATGTTAATGTAAATTTTGAAAAATCCAAACTTACATTCAGTTGT
  CTCGGAGGAAGTGATAATTTTAAGCATTTAAATGAAATTGATCTTTTTCACTGTATTGAT
  CCAAATGATTCCAAGCATAAAAGAACGGACAGATCAATTTTATGTTGTTTACGAAAAGGA
  GAATCTGGCCAGTCATGGCCAAGGTTAACAAAAGAAAGGGCAAAGCTTAATTGGCTTAGT
  GTCGACTTCAATAATTGGAAAGACTGGGAAGATGATTCAGATGAAGACATGTCTAATTTT
  GATCGTTTCTCTGAGATGATGAACAACATGGGTGGTGATGAGGATGTAGATTTACCAGAA
  GTAGATGGAGCAGATGATGATTCACAAGACAGTGATGATGAAAAAATGCCAGATCTGGAG
  TAAGGAATATTGTCATCACCTGGATTTTGAGAAAGAAAATAACTTCTCTGCAAGATTTCA
  TAATTGAGAGAATTCCTGAGTTGATAGCTCTNAAG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006601 unedited
  TGGCACTTCCAGGGCCGGNANAGCACTGGGGAGGGGTCACAGGGATGCCACCCGGGATCT
  GTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTT
  TAGTCTTCCAACAGTTTATTAGAAAGAATGTAGACATTTAAAAAAATCCCCACTGTCATG
  AACATAAATTGAGGTTTTCAGCCCGGGTATAAGCTGAATCAAAAAAAGGAAATAAAAAAT
  CCAATAGTGTATTAAACATTTTTCACTCATTTGCCATACTGACAGTGCAAATACAAATCT
  GGACTAAATGTACAGACTCTCAAGCAACAATGTACAGCTTTCTTCGTCCTCCATGCTAAG
  AGATGTAAAAGCTTAAGGGTCAAACAATACCAATTGTATAGGCTTCAAAAACCATCTAAG
  TTAGGGCATTCTCTAGTTTTAGCTAAGATACACCTGGAACACTGACAAGTCATCACTTAC
  ATAGAATAATGTGAAGTAAATTTTTTGAAAAATAAATTNTAGTGGAACAATCCTGAAGGA
  TAACACCAGAAGAATAGCAGGTTACCAGTAAGGTGTCAGCCAATTTGTTCCAGTCACTTT
  TGAATCCATGTTCTATAATCTAAAATTTATTCTCTTTCCCTAAGCTGAGAGCTTCCTATC
  ATGTCAGTATCTATGTTATGAAGAAAAGGAGACTTANGTGAGATGTTTTTATTTATCGCA
  ACTGCTGCATTATTTGCCTAGGACCTCAACAGCTTCATGAAAGTCGGGAAAATGTCATGC
  ATAAGGTTATTGCCTTANCTGACTTANAATTGCCCNATACATGGTACATATCAACCCTTA
  AGGAAGCCTTTTAAAANCAAACGGTTGAAAAATGGGTAAAGTANGCAAATACAGCTTTCT
  GCCTTC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006601
• Insert Size: 1500 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_006601.4, NP_006592.3
• RefSeq Size: 1490 bp
• RefSeq ORF: 483 bp
• Locus ID: 10728
• UniProt ID: Q15185
• Cytogenetics: 12
• Protein Families: Druggable Genome, Nuclear Hormone Receptor
• Gene Summary: This gene encodes an enzyme that converts prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). This protein functions as a co-chaperone with heat shock protein 90 (HSP90), localizing to response elements in DNA and disrupting transcriptional activation complexes. Alternative splicing results in multiple transcript variants. There are multiple pseudogenes of this gene on several different chromosomes. [provided by RefSeq, Feb 2016]
  Transcript Variant: This variant (1) encodes isoform a.