RALBP1 (NM_006788) Human Untagged Clone

SKU SC115848

RALBP1 (untagged)-Human ralA binding protein 1 (RALBP1)

Product Data

• Type: Human Untagged Clone
• Target Symbol: RALBP1
• Synonyms: RIP1; RLIP1; RLIP76
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC115848 sequence for NM_006788 edited (data generated by NextGen Sequencing); ATGACTGAGTGCTTCCTGCCCCCCACCAGCAGCCCCAGTGAACACCGCAGGGTGGAGCAT; GGCAGCGGGCTTACCCGGACCCCCAGCTCTGAAGAGATCAGCCCTACTAAGTTTCCTGGA; TTGTACCGCACTGGCGAGCCCTCACCTCCCCATGACATCCTCCATGAGCCTCCTGATGTA; GTGTCTGATGATGAGAAAGATCATGGGAAGAAAAAAGGGAAATTTAAGAAAAAGGAAAAG; AGGACTGAAGGCTATGCAGCCTTTCAGGAAGATAGCTCTGGAGATGAGGCAGAAAGTCCT; TCTAAAATGAAGAGGTCCAAGGGAATCCATGTTTTCAAGAAGCCCAGCTTTTCTAAAAAG; AAGGAAAAGGATTTTAAAATAAAAGAGAAACCCAAAGAAGAAAAGCATAAAGAAGAAAAG; CACAAAGAAGAAAAACATAAAGAGAAGAAGTCAAAAGACTTGACAGCAGCTGATGTTGTT; AAACAGTGGAAGGAAAAGAAGAAAAAGAAAAAGCCAATTCAGGAGCCAGAGGTGCCTCAG; ATTGATGTTCCAAATCTCAAACCCATTTTTGGAATTCCTTTGGCTGATGCAGTAGAGAGG; ACCATGATGTATGATGGCATTCGGCTGCCAGCCGTTTTCCGTGAATGTATAGATTACGTA; GAGAAGTATGGCATGAAGTGTGAAGGCATCTACAGAGTATCAGGAATTAAATCAAAGGTG; GATGAGCTAAAAGCAGCCTATGACCGGGAGGAGTCTACAAACTTGGAAGACTATGAGCCT; AACACTGTAGCCAGTTTGCTGAAGCAGTATTTGCGAGACCTTCCAGAGAATTTGCTTACC; AAAGAGCTTATGCCCAGATTTGAAGAGGCTTGTGGGAGGACCACGGAGACTGAGAAAGTG; CAGGAATTCCAGCGTTTACTCAAAGAACTGCCAGAATGTAACTATCTTCTGATTTCTTGG; CTCATTGTGCACATGGACCATGTCATTGCAAAGGAACTGGAAACAAAAATGAATATACAG; AACATTTCTATAGTGCTCAGCCCAACTGTGCAGATCAGCAATCGAGTCCTGTATGTGTTT; TTCACACATGTGCAAGAACTCTTTGGAAATGTGGTACTAAAGCAAGTGATGAAACCTCTG; CGATGGTCTAACATGGCCACGATGCCCACGCTGCCAGAGACCCAGGCGGGCATCAAGGAG; GAGATCAGGAGACAGGAGTTTCTTTTGAATTGTTTACATCGAGATCTGCAGGGTGGGATA; AAGGATTTGTCTAAAGAAGAAAGATTATGGGAAGTACAAAGAATTTTGACAGCCCTCAAA; AGAAAACTGAGAGAAGCTAAAAGACAGGAGTGTGAAACCAAGATTGCACAAGAGATAGCC; AGTCTTTCAAAAGAGGATGTTTCCAAAGAAGAGATGAATGAAAATGAAGAAGTTATAAAT; ATTCTCCTTGCTCAGGAGAATGAGATCCTGACTGAACAGGAGGAGCTCCTGGCCATGGAG; CAGTTTCTGCGCCGGCAGATTGCCTCAGAAAAAGAAGAGATTGAACGCCTCAGAGCTGAG; ATTGCTGAAATTCAGAGTCGCCAGCAGCACGGCCGAAGTGAGACTGAGGAGTACTCCTCC; GAGAGCGAGAGCGAGAGTGAGGATGAGGAGGAGCTGCAGATCATTCTGGAAGACTTACAG; AGACAGAACGAAGAGCTGGAAATAAAGAACAATCATTTGAATCAAGCAATTCATGAGGAG; CGCGAGGCCATCATCGAGCTGCGCGTGCAGCTGCGGCTGCTCCAGATGCAGCGAGCCAAG; GCCGAGCAGCAGGCGCAGGAGGACGAGGAGCCTGAGTGGCGCGGGGGTGCCGTCCAGCCG; CCCAGAGACGGCGTCCTTGAGCCAAAAGCAGCTAAAGAGCAGCCAAAGGCAGGCAAGGAG; CCGGCAAAGCCATCGCCCAGCAGGGATAGGAAGGAGACGTCCATCTGA; ; Clone variation with respect to NM_006788.3;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006788 unedited; ACTATAGGCGGCCGCGAATTCGGCACGAGGGGGAATGGGGCGCCCGAGGCCGGCCTGGGG; CGCAGCGCAAGAGGCGGCTCCGGTGGCTGCGGCGGCAGCGTGAGCGCGAGGAGGCGGAGG; CTGCGGCGGGGCGGACGGTCGCGCGGCGGCAGGCACAGGTGTAATGGATAGGTAACAGAG; AAGACCTCGTCCCTTCCTAGTCAGGGCATCAGCATGACTGAGTGCTTCCTGCCCCCCACC; AGCAGCCCCAGTGAACACCGCAGGGTGGAGCATGGCAGCGGGCTTACCCGGACCCCCAGC; TCTGAAGAGATCAGCCCTACTAAGTTTCCTGGATTGTACCGCACTGGCGAGCCCTCACCT; CCCCATGACATCCTCCATGAGCCTCCTGATGTAGTGTCTGATGATGAGAAAGATCATGGG; AAGAAAAAAGGGAAATTTAAGAAAAAGGAAAAGAGGACTGAAGGCTATGCAGCCTTTCAG; GAAGATAGCTCTGGAGATGAGGCAGAAAGTCCTTCTAAAATGAAGAGGTCCAAGGGAATC; CATGTTTTCAAGAAGCCCAGCTTTTCTAAAAAGAAGGAAAAGGATTTTAAAATAAAAGAG; AAACCCAAAGAAGAAAAGCATAAAGAAGAAAAGCACAAAGAAGAAAAACATAAAGAGAAG; AAGTCAAAAGACTTGACAGCAGCTGATGTTGTTAAACAGTGGAAGGAAAAGAAGAAAAGA; ANAAGCCAATTCAGGAGCCAGAGGTGCCTCAGATTGGATGTCCAAATCTCANACCCATTT; TTGGAATTCCTTTGGCTGATGCAGTANAGAGGACCATGATGTATGATGGCATTTCGCTGC; CAGCCCGTTTCCCGTGATGTATAGANACGTAAAGAAGTATGCATGAAGG;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006788 unedited; GCTGTTGATTTTTTGCTTGATCAATATGGTCCTGGCAAAATTAGTTAACCAATGCTGAGA; CATTTGTAATGAAATACTAATTTTAAAAATCCATGACACCTTGATAGAAATTAGAGTTTA; CACAAACAAAAAAGGAACCTTCGATATTGCCAGCAGCTATAAAGTGAACGTACTGAGACC; GACAGGACAGCAAGAAGGCATTTGCACATTTATATCTGACACCCGACCATACTTTCAGTC; ACCAGAATATCTTCTCTCCAGATTTAAAAAAATAGTATGCTGATTTCTATAACAAAGCTT; TTTTTCGTACAAAAATCAAATAATGGCCAACGAGTCACAACAGTGCAATAGGTAGAGGAA; GAAAAACTGCATCAAACAGGTGCTGAAAATAAATACTACCTAGGAGAAGGAGGTGAGAGC; CCTCGTGTGGGGTTTGTTTTCGACCCCTTGAGTGTGTGTGGGGTTTGTCTTCCGAGCCAC; GAGCCTGGCCTGTCTCGCGGTGCTGTTCACTCTGACAGAGTGCGCCTGCAGCACGTTGCC; TCCAGGGCCCAGCCTCCCAGAAGCCTCAGAGCATCAGAGTATCCGCCTCATCGGATGGAC; CAGAAACAAGAAAATGGGGTGGCGTGAATCACAGCTATCATTCACAGGAAAGGAATTTTT; TTTTATTGCTCAATCTTGTCAATTGGGAGTCCACCAGTAGGTTCACTGACACGATATGGA; TAATCCCCAACTTTTGCTCAAGAGCATATATATGTTTTATTCAAGCAAGGAGACGTGTAC; CTTCTATCCCAACCAAGCCACTCGAGCCATTCTGTCTTTAGGAAAGCCACCCCCCCAAAA; ATTTTTTGTTGGAACACATCCTTGTTGCAGACACAGGCAAGGTGACACCTTTGCCCCACC; ATGGAAAGGCCTTTGTTGTTCCGCAATGCAGAATGCCACGCCCGGCTATTTTCCCTCTTT; GTACCGCCCCCCCGGGCCGGTGGCCCGCTCCACAGAT;
• Restriction Sites: NotI-NotI
• ACCN: NM_006788
• Insert Size: 3670 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_006788.3, NP_006779.1
• RefSeq Size: 4368 bp
• RefSeq ORF: 1968 bp
• Locus ID: 10928
• UniProt ID: Q15311
• Cytogenetics: 18p11.22
• Domains: RhoGAP
• Protein Pathways: Pancreatic cancer, Pathways in cancer
• Summary: RALBP1 plays a role in receptor-mediated endocytosis and is a downstream effector of the small GTP-binding protein RAL (see RALA; MIM 179550). Small G proteins, such as RAL, have GDP-bound inactive and GTP-bound active forms, which shift from the inactive to the active state through the action of RALGDS (MIM 601619), which in turn is activated by RAS (see HRAS; MIM 190020) (summary by Feig, 2003 [PubMed 12888294]).[supplied by OMIM, Nov 2010]