FAF1 (NM_007051) Human Untagged Clone

SKU SC115760

FAF1 (untagged)-Human Fas (TNFRSF6) associated factor 1 (FAF1)

Product Data

• Type: Human Untagged Clone
• Target Symbol: FAF1
• Synonyms: CGI-03; hFAF1; HFAF1s; UBXD12; UBXN3A
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC115760 sequence for NM_007051 edited (data generated by NextGen Sequencing); ATGGCGTCCAACATGGACCGGGAGATGATCCTGGCGGATTTTCAGGCATGTACTGGCATT; GAAAACATTGACGAAGCTATTACATTGCTTGAACAAAATAATTGGGACTTAGTGGCAGCT; ATCAATGGTGTAATACCACAGGAAAATGGCATTCTACAAAGTGAATATGGAGGTGAGACC; ATACCAGGACCTGCATTTAATCCAGCAAGTCATCCAGCTTCAGCTCCTACTTCCTCTTCT; TCTTCAGCGTTTCGACCTGTAATGCCATCCAGGCAGATTGTAGAAAGGCAACCTCGGATG; CTGGACTTCAGGGTTGAATACAGAGACAGAAATGTTGATGTGGTACTTGAAGACACCTGT; ACTGTTGGAGAGATTAAACAGATTCTAGAAAATGAACTTCAGATACCTGTGTCCAAAATG; CTGTTAAAAGGCTGGAAGACGGGAGATGTGGAAGACAGTACGGTCCTAAAATCTCTACAC; TTGCCAAAAAACAACAGTCTTTATGTCCTTACACCAGATTTGCCACCACCTTCATCATCT; AGTCATGCTGGTGCCCTGCAGGAGTCATTAAATCAAAACTTCATGCTGATCATCACCCAC; CGAGAAGTCCAGCGGGAGTACAACCTGAACTTCTCAGGAAGCAGTACTATTCAAGAGGTA; AAGAGAAATGTGTATGACCTTACAAGTATCCCCGTTCGCCACCAATTATGGGAGGGCTGG; CCAACTTCTGCTACAGACGACTCAATGTGTCTTGCTGAATCAGGGCTCTCTTATCCCTGC; CATCGACTTACAGTGGGAAGAAGATCTTCACCTGCACAGACCCGGGAACAGTCGGAAGAA; CAAATCACCGATGTTCATATGGTTAGTGATAGCGATGGAGATGACTTTGAAGATGCTACA; GAATTTGGGGTGGATGATGGAGAAGTATTTGGCATGGCGTCATCTGCCTTGAGAAAATCT; CCAATGATGCCAGAAAACGCAGAAAATGAAGGAGATGCCTTATTACAATTTACAGCAGAG; TTTTCTTCAAGATATGGTGATTGCCATCCTGTATTTTTTATTGGCTCATTAGAAGCTGCT; TTTCAAGAGGCCTTCTATGTGAAAGCCCGAGATAGAAAGCTTCTTGCTATCTACCTCCAC; CATGATGAAAGTGTGTTAACCAACGTGTTCTGCTCACAAATGCTTTGTGCTGAATCCATT; GTTTCTTATCTGAGTCAAAATTTTATAACCTGGGCTTGGGATCTGACAAAGGACTCCAAC; AGAGCAAGATTTCTCACTATGTGCAATAGACACTTTGGCAGTGTTGTGGCACAAACCATT; CGGACTCAAAAAACGGATCAGTTTCCGCTTTTCCTGATTATTATGGGAAAGCGATCATCT; AATGAAGTGTTGAATGTGATACAAGGGAACACAACAGTAGATGAGTTAATGATGAGACTC; ATGGCTGCAATGGAGATCTTCACAGCCCAACAACAGGAAGATATAAAGGACGAGGATGAA; CGTGAAGCCAGAGAAAATGTGAAGAGAGAGCAAGATGAGGCCTATCGCCTTTCACTTGAG; GCTGACAGAGCAAAGAGGGAAGCTCACGAGAGAGAGATGGCAGAACAGTTTCGTTTGGAG; CAGATTCGCAAAGAACAAGAAGAGGAACGTGAGGCCATCCGGCTGTCCTTAGAGCAAGCC; CTGCCTCCTGAGCCAAAGGAAGAAAATGCTGAGCCTGTGAGCAAACTGCGGATCCGGACC; CCCAGTGGCGAGTTCTTGGAGCGGCGTTTCCTGGCCAGCAACAAGCTCCAGATTGTCTTT; GATTTTGTAGCTTCCAAAGGATTTCCATGGGATGAGTACAAGTTACTGAGCACCTTTCCT; AGGAGAGACGTAACTCAACTGGACCCAAATAAATCATTATTGGAGGTAAAGTTGTTCCCT; CAAGAAACCCTTTTCCTTGAAGCAAAAGAGTAA; ; Clone variation with respect to NM_007051.2;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_007051 unedited; TTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGCTGCCTCCCAGGTGCGC; GCTTCGCTCCCGGAGCCGCGGAACTCGGCGGCCGCCATGGCGTCCAACATGGACCGGGAG; ATGATCCTGGCGGATTTTCAGGCATGTACTGGCATTGAAAACATTGACGAAGCTATTACA; TTGCTTGAACAAAATAATTGGGACTTAGTGGCAGCTATCAATGGTGTAATACCACAGGAA; AATGGCATTCTACAAAGTGAATATGGAGGTGAGACCATACCAGGACCTGCATTTAATCCA; GCAAGTCATCCAGCTTCAGCTCCTACTTCCTCTTCTTCTTCAGCGTTTCGACCTGTAATG; CCATCCAGGCAGATTGTAGAAAGGCAACCTCGGATGCTGGACTTCAGGGTTGAATACAGA; GACAGAAATGTTGATGTGGTACTTGAAGACACCTGTACTGTTGGAGAGATTAAACAGATT; CTAGAAAATGAACTTCAGATACCTGTGTCCAAAATGCTGTTAAAAGGCTGGAAGACGGGA; GATGTGGAAGACAGTACGGTCCTAAAATCTCTACACTTGCCAAAAAACAACAGTCTTTAT; GTCCTTACACCAGATTTGCCACCACCTTCATCATCTAGTCATGCTGGGTGCCCTGCAGGA; GTCATTAAATCAAAACTTCATGCTGATCATCACCCACCGAGAAGTCCAGCGGGAGTACAA; CCTGAACTTCTCAGGAAGCAGTACTATTCAAGAGGTAAAGAGAAATGTGTATGACCTTAC; AAGTATCCCCGTTCGCCACCATTATGGGAGGNCTGGCCAACTTCTGCTACAGACGACTCA; ATGTGTCTTGCTGAATCANGGCTCTCTAATTCCTGCCATCGACTTA;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_007051 unedited; ACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTCTTAAGTAGCTATATTT; ATTATTACTTTTTCCAGCAATTTTGCAAGAGGCAGAAGTGTGACATTGAATTGAGTGAGA; CGAGCGTGTGGGTGGGTTGGCGAGGAGCCCTTCTCCTGACGCAGGCTGCTGGCTTGTCAA; GGAATGGCTGGTTCCACCGCTGGGCCGTGTTTACTCTTTTGCTTCAAGGAAAAGGGTTTC; TTGAGGGAACAACTTTACCTCCAATAATGATTTATTTGGGTCCAGTTGAGTTACGTCTCT; CCTAGGAAAGGTGCTCAGTAACTTGTACTCATCCCATGGAAATCCTTTGGAAGCTACAAA; ATCAAAGACAATCTGGAGCTTGTTGCTGGCCAGGAAACGCCGCTCCAAGAACTCGCCACT; GGGGGTCCGGATCCGCAGTTTGCTCACAGGCTCAGCATTTTCTTCCTTTGGCTCAGGAGG; CAGGGCTTGCTCTAAGGACAGCCGGATGGCCTCACGTTCCTCTTCTTGTTCTTTGCGAAT; CTGCTCCAAACGAAACTGTTCTGCCATCTCTCTCTCGTGAGCTTCCCTCTTTGCTCTGTC; AGCCTCAAGTGAAAGGCGATAGGCCTCATCTTGCTCTCTCTTCACATTTTCTCTGGCTTC; ACGTTCATCCTCGTCCTTTATATCTTCCTGTTGNTGGGCTGTGAAGATCTCCATTGCAGC; CATGAGTCTCATCATTAACTCATCTACTGGTGGNNGTCCCTTGTATCACATTCAACACTT; CATTAGATGATCCGCTTTCCCATAATAATCANGAAAAGCCGAAACTGATCCCGTTTTTGA; GTCCGAATGGTTTGTGCCCAACACTGCAAGTGTCTATGCACATAGTGAGAATCTTGCTTG; TTGGAGTCCTGGGCAATCCAACCCAGTTTAAATTTG;
• Restriction Sites: NotI-NotI
• ACCN: NM_007051
• Insert Size: 1880 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_007051.2, NP_008982.1
• RefSeq Size: 2610 bp
• RefSeq ORF: 1953 bp
• Locus ID: 11124
• UniProt ID: Q9UNN5
• Cytogenetics: 1p32.3
• Domains: UAS, UBX
• Protein Families: Druggable Genome
• Summary: Interaction of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number of organ systems. The protein encoded by this gene binds to FAS antigen and can initiate apoptosis or enhance apoptosis initiated through FAS antigen. Initiation of apoptosis by the protein encoded by this gene requires a ubiquitin-like domain but not the FAS-binding domain. [provided by RefSeq, Jul 2008]; Transcript Variant: This variant (1) is the longer transcript and encodes the full-length isoform (a).