BAMBI (NM_012342) Human Untagged Clone

SKU SC115396

BAMBI (untagged)-Human BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) (BAMBI)

Product Data

• Type: Human Untagged Clone
• Target Symbol: BAMBI
• Synonyms: NMA
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC115396 sequence for NM_012342 edited (data generated by NextGen Sequencing); ATGGATCGCCACTCCAGCTACATCTTCATCTGGCTGCAGCTGGAGCTCTGCGCCATGGCC; GTGCTGCTCACCAAAGGTGAAATTCGATGCTACTGTGATGCTGCCCACTGTGTAGCCACT; GGTTATATGTGTAAATCTGAGCTCAGCGCCTGCTTCTCTAGACTTCTTGATCCTCAGAAC; TCAAATTCCCCACTCACCCATGGCTGCCTGGACTCTCTTGCAAGCACGACAGACATCTGC; CAAGCCAAACAGGCCCGAAACCACTCTGGCACCACCATACCCACATTGGAATGCTGTCAT; GAAGACATGTGCAATTACAGAGGGCTGCACGATGTTCTCTCTCCTCCCAGGGGTGAGGCC; TCAGGACAAGGAAACAGGTATCAGCATGATGGTAGCAGAAACCTTATCACCAAGGTGCAG; GAGCTGACTTCTTCCAAAGAGTTGTGGTTCCGGGCAGCGGTCATTGCCGTGCCCATTGCT; GGAGGGCTGATTTTAGTGTTGCTTATTATGTTGGCCCTGAGGATGCTTCGAAGTGAAAAT; AAGAGGCTGCAGGATCAGCGGCAACAGATGCTCTCCCGTTTGCACTACAGCTTTCACGGA; CACCATTCCAAAAAGGGGCAGGTTGCAAAGTTAGACTTGGAATGCATGGTGCCGGTCAGT; GGGCACGAGAACTGCTGTCTGACCTGTGATAAAATGAGACAAGCAGACCTCAGCAACGAT; AAGATCCTCTCGCTTGTTCACTGGGGCATGTACAGTGGGCACGGGAAGCTGGAATTCGTA; TGA; ; Clone variation with respect to NM_012342.2;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_012342 unedited; TTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGAGAGAGAGAGAG; AACTGGGCTGGCGCGGGCGGGAGCTGCGGCGGATACCCTTGCGTGCTGTGGAGACCCTAC; TCTCTTCGCTGAGAACGGCCGCTAGCGGGGACTGAAGGCCGGGAGCCCACTCCCGACCCG; GGGCTAGCGTGCGTCCCTAGAGTCGAGCGGGGCAAGGGAGCCAGTGGCCGCCGACGGGGG; ACCGGGAAACTTTTCTGGGCTCCTGGGCGCGCCCTGTAGCCGCGCTCCATGCTCCGGCAG; CGGCCCGAAACCCAGCCCCGCCGCTGACGGCGCCCGCCGCTCCGGGCAGGGCCCATGCCC; TGCGCGCTCCGGGGGTCGTAGGCTGCCGCCGAGCCGGGGCTCCGGAAGCCGGCGGGGGCG; CCGCGGCCGTGCGGGGCGTCAATGGATCGCCACTCCAGCTACATCTTCATCTGGCTGCAG; CTGGAGCTCTGCGCCATGGCCGTGCTGCTCACCAAAGGTGAAATTCGATGCTACTGTGAT; GCTGCCCACTGTGTAGCCACTGGTTATATGTGTAAATCTGAGCTCAGCGCCTGCTTCTCT; AGACTTCTTGATCCTCAGAACTCAAATTCCCCACTCACCCATGGCTGCCTGGACTCTCTT; GCAAGCACGACAGACATCTGCCAAGCCAAACAGGCCCGAAACCACTCTGGCACCACCATA; CCCACATTGGAATGCTGTCATGAAGACATGTGCCATTACAGAGGGCTGCACGATGTTCTC; TCTCCTCCAGGGGTGATGCCTCAGGACAAGGAACCAGTATCACCATGATGTTAGCAGAAA; CTTATCACCAGTGCAAGAGCTGACTCCTCCAAGAAGTGGTGGTCCGGGCAGCGGTCATTG; CCGGCCCATG;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_012342 unedited; GTCGGAGCTCCGCCTGCGGGGNNCGAGAAAAAACTTTTCTTTTTTGGTGGTTAGTTGGTT; TTTTTTTCTTTTTTGGGGGGAGGCATACACATTGGAAAAGTATTCCGGAACACCTGGATC; AAAATGACCTTTGCTAGGTCAACTCCAGAAATTGATCAATCATATCTGACCTGGTACACA; TAAATTCCAGATCTCCTTCTTAAATGAAGTCCATACCAGAGTTATCCTATAGCCAGAATG; GGGGTAAGACACTAAAAGATGGGCAGTATACATTTAGAAACTCCACACTGTAAGAAAATT; ACACAGGCACATGGAAGAATAAGCAAGATCTTGGTCTTGTTTAAAAAAGAAAAGAGAAAA; AAAAAAACCAAGCCACATCCTAGAGTTGAGAACAAATTATTAACAGCAAATGGCCATTTG; TATAATTAACATGTACTGTCTCACGTTTCCCAGTTAAATTTATGAAAGACACTATTAAAT; TTCAGACAAAATATATATATCCCTTTTAAATCTTTACAATAAATCAAGATGTAGAAGCTC; ACATAGGGCACATTTTTGCTTATTTAGGTACTCAATTCCAGCTCCCTTGGATGCAAATAA; CCCTGGGGACAGTGGGCACAAAGGCTTCTCTTTGCTTTTTATAATTTTAAAGCAAATAAC; ACATTTAACTGCATTTAAGCCTGTGCCAAAAATCCCTTCAGAGGAAACATCCAAGAATCT; GGTCGCAGAGGTCACTTTGTCTCTCAAAGATGATTAAAAGAGCTTGGCCACCAAAAAAGG; GGCTCTGGCCAGCCAAACTCACAAGGCCTCCAAGCTGTCCAGTAAGGGGAGTTCAAATAG; ACTCCGTCATAGAAATCCCAGTCCCGGGCCCCTGTCCTGCCCCATGAACACCGAGAGAAC; TTACCGCGCTGAGCCGGCCTGCCAATTAAACAGAC;
• Restriction Sites: NotI-NotI
• ACCN: NM_012342
• Insert Size: 2190 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_012342.2, NP_036474.1
• RefSeq Size: 1732 bp
• RefSeq ORF: 783 bp
• Locus ID: 25805
• UniProt ID: Q13145
• Cytogenetics: 10p12.1
• Protein Families: Transmembrane
• Summary: This gene encodes a transmembrane glycoprotein related to the type I receptors of the transforming growth factor-beta (TGF-beta) family, whose members play important roles in signal transduction in many developmental and pathological processes. The encoded protein however is a pseudoreceptor, lacking an intracellular serine/threonine kinase domain required for signaling. Similar proteins in frog, mouse and zebrafish function as negative regulators of TGF-beta, which has led to the suggestion that the encoded protein may function to limit the signaling range of the TGF-beta family during early embryogenesis. [provided by RefSeq, Jul 2008]