SAP102 (DLG3) (NM_021120) Human Untagged Clone

CAT#: SC112969

DLG3 (untagged)-Human discs, large homolog 3 (Drosophila) (DLG3), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SAP102
• Synonyms: MRX; MRX90; NEDLG; PPP1R82; SAP102; XLMR
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_021120 edited
  CAGAAGCGGTCCTCACAGCACCCATTCTCTGCTTGAGCTCCCGCTTCTTCTTTGCCGCTG
  GGCCTCGGCCCAGAAGCCACGACGGGCGACACGGAGCCGCCAGTGCTGGAGGGGGAGCCG
  TGGGTGCGGGGCAGCGTGGGGGCCGAGGCCCCGGGACGCCCGCCCGGCCCCAGGCCCCGC
  TCAGCCCGGGCGCCCCCACGGGTGCCCCCCCCTTCTTGGTCCGAGCAGTGTGAGTGTGCC
  AGGGAGCCCGGCGGCGGCGGCGGCGGTGGTGGCGGCGGTGGCGGCGGCGTGGAATCCGGC
  GTGGGCTGGGGGGTCCGAGCCGCGGGGGGCAGTGCCATGCACAAGCACCAGCACTGCTGT
  AAGTGCCCTGAGTGCTATGAGGTGACCCGCCTGGCCGCCCTGCGGCGCCTCGAGCCTCCG
  GGCTACGGCGACTGGCAAGTCCCCGACCCTTACGGGCCAGGTGGGGGCAACGGCGCCAGC
  GCGGGTTATGGGGGCTACAGCTCGCAGACCTTGCCCTCGCAGGCGGGGGCCACCCCCACC
  CCTCGCACCAAGGCCAAGCTCATCCCCACCGGCCGGGATGTGGGGCCGGTGCCTCCTAAG
  CCAGTCCCGGGCAAGAGCACCCCCAAACTCAACGGCAGCGGCCCCAGCTGGTGGCCAGAG
  TGCACCTGTACCAACCGGGACTGGTATGAGCAGGTGAATGGCAGTGATGGCATGTTCAAA
  TATGAGGAAATCGTACTTGAGAGGGGCAACTCTGGCCTGGGCTTCAGTATCGCAGGTGGC
  ATCGACAATCCCCATGTCCCTGATGACCCTGGCATCTTTATTACCAAGATTATCCCTGGT
  GGAGCAGCTGCCATGGATGGGAGGCTGGGGGTGAATGACTGTGTGCTGCGGGTGAATGAG
  GTGGACGTGTCGGAGGTGGTACACAGCCGGGCGGTGGAGGCGCTGAAGGAGGCAGGCCCT
  GTGGTGCGATTGGTGGTGCGGAGGCGACAGCCTCCACCCGAGACCATCATGGAGGTCAAC
  CTGCTCAAAGGGCCCAAAGGCCTGGGTTTCAGCATTGCTGGGGGTATTGGCAACCAGCAC
  ATCCCAGGAGACAACAGCATCTACATCACCAAGATCATTGAGGGGGGTGCTGCTCAGAAG
  GATGGACGCCTACAGATTGGGGACCGGCTGCTGGCGGTGAACAACACCAATCTGCAGGAT
  GTGAGGCACGAGGAAGCTGTGGCCTCACTGAAGAACACATCTGATATGGTGTATTTGAAG
  GTGGCCAAGCCAGGCAGCCTCCACCTCAACGACATGTACGCTCCCCCTGACTACGCCAGC
  ACTTTTACTGCCTTGGCTGACAACCACATAAGCCATAATTCCAGCCTGGGTTATCTCGGG
  GCTGTGGAGAGCAAGGTCAGCTACCCTGCTCCTCCTCAGGTTCCCCCCACCCGCTACTCT
  CCTATTCCCAGGCACATGCTGGCTGAGGAGGACTTCACCAGAGAGCCTCGCAAGATCATC
  CTGCACAAAGGCTCCACAGGCCTGGGCTTCAACATCGTAGGAGGAGAGGATGGAGAAGGC
  ATTTTTGTCTCCTTCATCCTGGCAGGAGGCCCAGCTGACCTGAGTGGGGAGCTGCGCAGG
  GGAGACCGGATCTTATCGGTGAATGGAGTGAATCTGAGGAATGCAACTCATGAGCAGGCT
  GCAGCTGCTCTGAAACGGGCCGGCCAGTCAGTCACCATTGTGGCCCAGTACAGACCTGAA
  GAATACAGTCGCTTTGAATCGAAGATACATGACTTACGAGAACAAATGATGAACAGCAGC
  ATGAGCTCTGGGTCTGGGTCCCTCCGAACAAGTGAAAAGAGGTCCTTGTATGTCAGGGCC
  CTGTTTGATTATGATCGGACTCGGGACAGCTGCCTGCCAAGCCAGGGGCTCAGCTTCTCT
  TATGGTGACATTCTGCATGTCATTAATGCCTCTGATGATGAGTGGTGGCAGGCAAGGCTG
  GTGACCCCACACGGAGAAAGTGAGCAGATCGGTGTGATCCCCAGTAAGAAGAGGGTGGAA
  AAGAAAGAAAGAGCTCGATTGAAAACTGTGAAGTTCCATGCCAGGACGGGGATGATTGAG
  TCTAACAGGGACTTCCCGGGGTTAAGTGACGATTATTATGGAGCAAAGAACCTGAAAGGA
  CAAGAGGATGCTATTTTGTCATATGAGCCAGTGACACGGCAAGAAATTCACTATGCAAGG
  CCTGTGATCATCCTGGGCCCAATGAAGGACCGAGTCAATGATGACCTGATCTCCGAATTT
  CCACATAAATTTGGATCCTGTGTGCCACATACTACCCGGCCTCGACGTGATAATGAGGTG
  GATGGACAAGACTACCACTTTGTGGTGTCCCGAGAACAAATGGAGAAAGATATTCAGGAC
  AACAAGTTCATCGAGGCGGGCCAATTTAATGATAACCTCTATGGGACCAGCATCCAGTCA
  GTGCGGGCAGTTGCAGAGAGGGGCAAGCACTGCATCTTAGATGTTTCCGGCAATGCTATC
  AAGAGACTGCAGCAAGCACAACTTTACCCCATTGCCATTTTCATCAAGCCCAAGTCCATT
  GAAGCCCTTATGGAAATGAACCGAAGGCAGACATATGAACAAGCAAATAAGATCTATGAC
  AAAGCCATGAAACTGGAGCAGGAATTTGGAGAGTACTTTACAGCCATTGTACAGGGTGAC
  TCACTGGAAGAGATTTATAACAAAATCAAACAAATCATTGAGGACCAGTCTGGGCACTAC
  ATTTGGGTCCCATCCCCTGAAAAACTCTGAAGAATCCCCTCCAACCATTCTCTTGTGAAC
  AGAAGAAATCAAGTCCCTCTTCCCTCCTCCCTCTTCATTCCTGTCCCCATGGGGAGAACA
  AATGCTACTGTTCTTGTCCCCTTTTTTAGATATGTCAAAAAAAATTAAGTTTTCTAGTCC
  TGTTCTTTTTTTTTTTTTAAGTTTTTGTTTGTTTCAGTTTATTTTTTGGGATGATGCCAT
  CTCATTCATCATGTGACTGTGCCCATTCCTGCATGGACCTTTCCCAAGCGCTAGCACAGG
  TGCAAAATC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_021120 unedited
  GATTTTGTGATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGGGGACCAGAG
  CAGAAGCGGTCCTCACAGCACCCATTCTCTGCTTGAGCTCCCGCTTCTTCTTTGCCGCTG
  GGCCTCGGCCCAGAAGCCACGACGGGCGACACGGAGCCGCCAGTGCTGGAGGGGGAGCCG
  TGGGTGCGGGGCAGCGTGGGGGCCGAGGCCCCGGGACGCCCGCCCGGCCCCAGGCCCCGC
  TCAGCCCGGGCGCCCCCACGGGTGCCCCCCCCTTCTTGGTCCGAGCAGTGTGAGTGTGCC
  AGGGAGCCCGGCGGCGGCGGCGGCGGTGGTGGCGGCGGTGGCGGCGGCGTGGAATCCGGC
  GTGGGCTGGGGGGTCCGAGCCGCGGGGGGCAGTGCCATGCACAAGCACCAGCACTGCTGT
  AAGTGCCCTGAGTGCTATGAGGTGACCCGCCTGGCCGCCCTGCGGCGCCTCGAGCCTCCG
  GGCTACGGCGACTGGCAAGTCCCCGACCCTTACGGGCCAGGTGGGGGCAACGGCGCCAGC
  GCGGGTTATGGGGGCTACAGCTCGCAATACTTGCCTCGCAGGCGGGGGCCACCCCACCCC
  TCGCACCAGGCCAAGCTCATCCCCACCGGCCGGGATGTGGGGCCGGTGCCTTCTTAGCCA
  GTCCCGGGCAAGAGCACCCCCAAACTCAACGGCAGCGGGCCCCAGCTTGTTGGCCANAGT
  GCACCTGTACCAACCGGGACTGGTATGAGCANGTGAATGGCAGTGATGGCATGTTCAATA
  TGAGGAAATCGTACTTGAGAGGGGCAACTCTGGCCCTGGCTTAGTATCGCAGGTGCACGA
  CATCCCATGTCTGTACCTGCTCTTATACAAATTCTGGACCTCTATAGTGATTCTGAAGCT
  AGACCGGCAGCTGTGGGACCACTAACGTGTCGCNNNNNNNNNTNNNNNNNNCNCNNCCAN
  NNNNNCNCCTCCCTCCNCCCNCCACCCCCCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_021120
• Insert Size: 4500 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_021120.1, NP_066943.1
• RefSeq Size: 3100 bp
• RefSeq ORF: 2454 bp
• Locus ID: 1741
• UniProt ID: Q92796
• Cytogenetics: Xq13.1
• Domains: SH3, PDZ, Guanylate_kin, GuKc
• Gene Summary: This gene encodes a member of the membrane-associated guanylate kinase protein family. The encoded protein may play a role in clustering of NMDA receptors at excitatory synapses. It may also negatively regulate cell proliferation through interaction with the C-terminal region of the adenomatosis polyposis coli tumor suppressor protein. Mutations in this gene have been associated with X-linked cognitive disability. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).