SAP102 (DLG3) (NM_021120) Human Untagged Clone

SKU SC112969

DLG3 (untagged)-Human discs, large homolog 3 (Drosophila) (DLG3), transcript variant 1

Product Data

• Type: Human Untagged Clone
• Target Symbol: SAP102
• Synonyms: MRX; MRX90; NEDLG; PPP1R82; SAP102; XLMR
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_021120 edited; CAGAAGCGGTCCTCACAGCACCCATTCTCTGCTTGAGCTCCCGCTTCTTCTTTGCCGCTG; GGCCTCGGCCCAGAAGCCACGACGGGCGACACGGAGCCGCCAGTGCTGGAGGGGGAGCCG; TGGGTGCGGGGCAGCGTGGGGGCCGAGGCCCCGGGACGCCCGCCCGGCCCCAGGCCCCGC; TCAGCCCGGGCGCCCCCACGGGTGCCCCCCCCTTCTTGGTCCGAGCAGTGTGAGTGTGCC; AGGGAGCCCGGCGGCGGCGGCGGCGGTGGTGGCGGCGGTGGCGGCGGCGTGGAATCCGGC; GTGGGCTGGGGGGTCCGAGCCGCGGGGGGCAGTGCCATGCACAAGCACCAGCACTGCTGT; AAGTGCCCTGAGTGCTATGAGGTGACCCGCCTGGCCGCCCTGCGGCGCCTCGAGCCTCCG; GGCTACGGCGACTGGCAAGTCCCCGACCCTTACGGGCCAGGTGGGGGCAACGGCGCCAGC; GCGGGTTATGGGGGCTACAGCTCGCAGACCTTGCCCTCGCAGGCGGGGGCCACCCCCACC; CCTCGCACCAAGGCCAAGCTCATCCCCACCGGCCGGGATGTGGGGCCGGTGCCTCCTAAG; CCAGTCCCGGGCAAGAGCACCCCCAAACTCAACGGCAGCGGCCCCAGCTGGTGGCCAGAG; TGCACCTGTACCAACCGGGACTGGTATGAGCAGGTGAATGGCAGTGATGGCATGTTCAAA; TATGAGGAAATCGTACTTGAGAGGGGCAACTCTGGCCTGGGCTTCAGTATCGCAGGTGGC; ATCGACAATCCCCATGTCCCTGATGACCCTGGCATCTTTATTACCAAGATTATCCCTGGT; GGAGCAGCTGCCATGGATGGGAGGCTGGGGGTGAATGACTGTGTGCTGCGGGTGAATGAG; GTGGACGTGTCGGAGGTGGTACACAGCCGGGCGGTGGAGGCGCTGAAGGAGGCAGGCCCT; GTGGTGCGATTGGTGGTGCGGAGGCGACAGCCTCCACCCGAGACCATCATGGAGGTCAAC; CTGCTCAAAGGGCCCAAAGGCCTGGGTTTCAGCATTGCTGGGGGTATTGGCAACCAGCAC; ATCCCAGGAGACAACAGCATCTACATCACCAAGATCATTGAGGGGGGTGCTGCTCAGAAG; GATGGACGCCTACAGATTGGGGACCGGCTGCTGGCGGTGAACAACACCAATCTGCAGGAT; GTGAGGCACGAGGAAGCTGTGGCCTCACTGAAGAACACATCTGATATGGTGTATTTGAAG; GTGGCCAAGCCAGGCAGCCTCCACCTCAACGACATGTACGCTCCCCCTGACTACGCCAGC; ACTTTTACTGCCTTGGCTGACAACCACATAAGCCATAATTCCAGCCTGGGTTATCTCGGG; GCTGTGGAGAGCAAGGTCAGCTACCCTGCTCCTCCTCAGGTTCCCCCCACCCGCTACTCT; CCTATTCCCAGGCACATGCTGGCTGAGGAGGACTTCACCAGAGAGCCTCGCAAGATCATC; CTGCACAAAGGCTCCACAGGCCTGGGCTTCAACATCGTAGGAGGAGAGGATGGAGAAGGC; ATTTTTGTCTCCTTCATCCTGGCAGGAGGCCCAGCTGACCTGAGTGGGGAGCTGCGCAGG; GGAGACCGGATCTTATCGGTGAATGGAGTGAATCTGAGGAATGCAACTCATGAGCAGGCT; GCAGCTGCTCTGAAACGGGCCGGCCAGTCAGTCACCATTGTGGCCCAGTACAGACCTGAA; GAATACAGTCGCTTTGAATCGAAGATACATGACTTACGAGAACAAATGATGAACAGCAGC; ATGAGCTCTGGGTCTGGGTCCCTCCGAACAAGTGAAAAGAGGTCCTTGTATGTCAGGGCC; CTGTTTGATTATGATCGGACTCGGGACAGCTGCCTGCCAAGCCAGGGGCTCAGCTTCTCT; TATGGTGACATTCTGCATGTCATTAATGCCTCTGATGATGAGTGGTGGCAGGCAAGGCTG; GTGACCCCACACGGAGAAAGTGAGCAGATCGGTGTGATCCCCAGTAAGAAGAGGGTGGAA; AAGAAAGAAAGAGCTCGATTGAAAACTGTGAAGTTCCATGCCAGGACGGGGATGATTGAG; TCTAACAGGGACTTCCCGGGGTTAAGTGACGATTATTATGGAGCAAAGAACCTGAAAGGA; CAAGAGGATGCTATTTTGTCATATGAGCCAGTGACACGGCAAGAAATTCACTATGCAAGG; CCTGTGATCATCCTGGGCCCAATGAAGGACCGAGTCAATGATGACCTGATCTCCGAATTT; CCACATAAATTTGGATCCTGTGTGCCACATACTACCCGGCCTCGACGTGATAATGAGGTG; GATGGACAAGACTACCACTTTGTGGTGTCCCGAGAACAAATGGAGAAAGATATTCAGGAC; AACAAGTTCATCGAGGCGGGCCAATTTAATGATAACCTCTATGGGACCAGCATCCAGTCA; GTGCGGGCAGTTGCAGAGAGGGGCAAGCACTGCATCTTAGATGTTTCCGGCAATGCTATC; AAGAGACTGCAGCAAGCACAACTTTACCCCATTGCCATTTTCATCAAGCCCAAGTCCATT; GAAGCCCTTATGGAAATGAACCGAAGGCAGACATATGAACAAGCAAATAAGATCTATGAC; AAAGCCATGAAACTGGAGCAGGAATTTGGAGAGTACTTTACAGCCATTGTACAGGGTGAC; TCACTGGAAGAGATTTATAACAAAATCAAACAAATCATTGAGGACCAGTCTGGGCACTAC; ATTTGGGTCCCATCCCCTGAAAAACTCTGAAGAATCCCCTCCAACCATTCTCTTGTGAAC; AGAAGAAATCAAGTCCCTCTTCCCTCCTCCCTCTTCATTCCTGTCCCCATGGGGAGAACA; AATGCTACTGTTCTTGTCCCCTTTTTTAGATATGTCAAAAAAAATTAAGTTTTCTAGTCC; TGTTCTTTTTTTTTTTTTAAGTTTTTGTTTGTTTCAGTTTATTTTTTGGGATGATGCCAT; CTCATTCATCATGTGACTGTGCCCATTCCTGCATGGACCTTTCCCAAGCGCTAGCACAGG; TGCAAAATC;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_021120 unedited; GATTTTGTGATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGGGGACCAGAG; CAGAAGCGGTCCTCACAGCACCCATTCTCTGCTTGAGCTCCCGCTTCTTCTTTGCCGCTG; GGCCTCGGCCCAGAAGCCACGACGGGCGACACGGAGCCGCCAGTGCTGGAGGGGGAGCCG; TGGGTGCGGGGCAGCGTGGGGGCCGAGGCCCCGGGACGCCCGCCCGGCCCCAGGCCCCGC; TCAGCCCGGGCGCCCCCACGGGTGCCCCCCCCTTCTTGGTCCGAGCAGTGTGAGTGTGCC; AGGGAGCCCGGCGGCGGCGGCGGCGGTGGTGGCGGCGGTGGCGGCGGCGTGGAATCCGGC; GTGGGCTGGGGGGTCCGAGCCGCGGGGGGCAGTGCCATGCACAAGCACCAGCACTGCTGT; AAGTGCCCTGAGTGCTATGAGGTGACCCGCCTGGCCGCCCTGCGGCGCCTCGAGCCTCCG; GGCTACGGCGACTGGCAAGTCCCCGACCCTTACGGGCCAGGTGGGGGCAACGGCGCCAGC; GCGGGTTATGGGGGCTACAGCTCGCAATACTTGCCTCGCAGGCGGGGGCCACCCCACCCC; TCGCACCAGGCCAAGCTCATCCCCACCGGCCGGGATGTGGGGCCGGTGCCTTCTTAGCCA; GTCCCGGGCAAGAGCACCCCCAAACTCAACGGCAGCGGGCCCCAGCTTGTTGGCCANAGT; GCACCTGTACCAACCGGGACTGGTATGAGCANGTGAATGGCAGTGATGGCATGTTCAATA; TGAGGAAATCGTACTTGAGAGGGGCAACTCTGGCCCTGGCTTAGTATCGCAGGTGCACGA; CATCCCATGTCTGTACCTGCTCTTATACAAATTCTGGACCTCTATAGTGATTCTGAAGCT; AGACCGGCAGCTGTGGGACCACTAACGTGTCGCNNNNNNNNNTNNNNNNNNCNCNNCCAN; NNNNNCNCCTCCCTCCNCCCNCCACCCCCCC;
• Restriction Sites: NotI-NotI
• ACCN: NM_021120
• Insert Size: 4500 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_021120.1, NP_066943.1
• RefSeq Size: 3100 bp
• RefSeq ORF: 2454 bp
• Locus ID: 1741
• UniProt ID: Q92796
• Cytogenetics: Xq13.1
• Domains: Guanylate_kin, GuKc, PDZ, SH3
• Summary: This gene encodes a member of the membrane-associated guanylate kinase protein family. The encoded protein may play a role in clustering of NMDA receptors at excitatory synapses. It may also negatively regulate cell proliferation through interaction with the C-terminal region of the adenomatosis polyposis coli tumor suppressor protein. Mutations in this gene have been associated with X-linked cognitive disability. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009]; Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).