Aldehyde Oxidase (AOX1) (NM_001159) Human Untagged Clone

SKU SC110827

AOX1 (untagged)-Human aldehyde oxidase 1 (AOX1)

Product Data

• Type: Human Untagged Clone
• Target Symbol: Aldehyde Oxidase
• Synonyms: AO; AOH1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC110827 sequence for NM_001159 edited (data generated by NextGen Sequencing); ATGGACCGGGCGTCCGAGCTGCTCTTCTACGTGAACGGCCGCAAGGTGATAGAAAAAAAT; GTCGATCCTGAAACAATGCTGTTGCCTTATTTGAGGAAGAAGCTTCGACTCACAGGAACT; AAGTATGGCTGTGGAGGAGGAGGCTGTGGTGCTTGTACAGTGATGATATCACGATACAAC; CCCATCACCAAGAGGATAAGGCATCACCCAGCCAATGCCTGTCTGATTCCCATCTGTTCT; CTGTATGGTGCTGCCGTCACCACAGTAGAAGGCATAGGAAGCACCCACACCAGAATTCAT; CCTGTTCAGGAGAGGATTGCCAAGTGTCATGGCACCCAGTGTGGCTTCTGCACACCTGGG; ATGGTGATGTCCATCTACACGCTGCTCAGGAACCACCCAGAGCCCACTCTGGATCAGTTA; ACTGATGCCCTTGGTGGTAACCTGTGCCGTTGCACTGGATACAGGCCCATAATTGATGCA; TGCAAGACTTTCTGTAAAACTTCGGGCTGCTGTCAAAGTAAAGAAAATGGGGTTTGCTGT; TTGGATCAAGGAATCAATGGATTGCCAGAATTTGAGGAAGGAAGTAAGACAAGTCCAAAA; CTCTTCGCAGAAGAGGAGTTTCTGCCATTGGATCCAACCCAGGAACTGATATTTCCTCCT; GAGCTAATGATAATGGCTGAGAAACAGTCGCAAAGGACCAGGGTGTTTGGCAGTGAGAGA; ATGATGTGGTTTTCCCCCGTGACCCTGAAGGAACTGCTGGAATTTAAATTCAAGTATCCC; CAGGCTCCTGTTATCATGGGAAACACCTCTGTGGGGCCTGAAGTGAAATTTAAAGGCGTC; TTTCACCCAGTTATAATTTCTCCTGATAGAATTGAAGAACTGAGTGTTGTAAACCATGCA; TATAATGGACTCACCCTTGGTGCTGGTCTCAGCCTAGCCCAGGTGAAGGACATTTTGGCT; GATGTAGTCCAGAAGCTTCCAGAGGAGAAGACACAGATGTACCATGCTCTCCTGAAGCAT; TTGGGAACTCTGGCTGGGTCCCAGATCAGGAACATGGCTTCTTTAGGGGGACACATCATT; AGCAGGCATCCAGATTCAGATCTGAATCCCATCCTGGCTGTGGGTAACTGTACCCTCAAC; TTGCTATCAAAAGAAGGAAAACGACAGATTCCTTTAAATGAGCAATTCCTCAGCAAGTGC; CCTAATGCAGATCTTAAGCCTCAAGAAATCTTGGTCTCAGTGAACATCCCCTACTCAAGG; AAGTGGGAATTTGTGTCAGCCTTCCGACAAGCCCAGCGACAGGAGAATGCGCTAGCGATA; GTCAATTCAGGAATGAGAGTCTTTTTTGGAGAAGGGGATGGCATTATTAGAGAGTTATGC; ATCTCATATGGAGGCGTTGGTCCAGCCACCATCTGTGCCAAGAATTCCTGCCAGAAACTC; ATTGGAAGGCACTGGAACGAACAGATGCTGGATATAGCCTGCAGGCTTATTCTGAATGAA; GTCTCCCTTTTGGGCTCGGCGCCAGGTGGGAAAGTGGAGTTCAAGAGGACTCTCATCATC; AGCTTCCTCTTCAAGTTCTACCTGGAAGTGTCACAGATTTTGAAAAAGATGGATCCAGTT; CACTATCCTAGCCTTGCAGACAAGTATGAAAGTGCTTTAGAAGATCTTCATTCCAAACAT; CACTGCAGTACATTAAAGTACCAGAATATAGGCCCAAAGCAGCATCCTGAAGACCCAATT; GGCCACCCCATCATGCATCTGTCTGGTGTGAAGCATGCCACGGGGGAGGCCATCTACTGT; GATGACATGCCTCTGGTGGACCAGGAACTTTTCTTGACTTTTGTGACTAGTTCAAGAGCT; CATGCTAAGATTGTGTCTATTGATCTGTCAGAAGCTCTCAGCATGCCCGGTGTGGTGGAC; ATCATGACAGCAGAACATCTTAGTGACGTCAACTCCTTCTGCTTTTTTACTGAAGCTGAG; AAATTTCTGGCGACAGATAAGGTGTTCTGTGTGGGTCAGCTTGTCTGTGCTGTGCTTGCC; GATTCTGAGGTTCAGGCAAAGCGAGCTGCTAAGCGAGTGAAGATTGTCTATCAAGACTTG; GAGCCGCTGATACTAACAATTGAGGAAAGTATACAACACAACTCCTCCTTCAAGCCAGAA; AGGAAACTGGAATATGGAAATGTTGACGAAGCATTTAAAGTGGTTGATCAAATTCTTGAA; GGTGAAATACATATGGGAGGTCAAGAACATTTTTATATGGAAACCCAAAGCATGCTTGTC; GTTCCCAAGGGAGAGGATCAAGAAATGGATGTCTACGTGTCCACACAGTTTCCCAAATAT; ATACAGGACATTGTTGCCTCAACCTTGAAGCTCCCAGCTAACAAGGTCATGTGCCATGTA; AGGCGTGTTGGTGGAGCGTTTGGAGGGAAGGTGTTAAAAACCGGAATCATTGCAGCCGTC; ACTGCATTTGCCGCAAACAAACATGGCCGTGCAGTTCGCTGTGTTCTGGAACGAGGAGAA; GACATGTTAATAACTGGAGGCCGCCATCCTTACCTTGGAAAGTACAAAGCTGGATTCATG; AACGATGGCAGAATCTTGGCCCTGGACATGGAGCATTACAGCAATGCAGGCGCCTCCTTG; GATGAATCATTATTCGTGATAGAAATGGGACTTCTGAAAATGGACAATGCTTACAAGTTT; CCCAATCTCCGCTGCCGGGGTTGGGCATGCAGAACCAACCTTCCATCCAACACAGCTTTT; CGTGGGTTTGGCTTTCCTCAGGCAGCGCTGATCACCGAATCTTGTATCACGGAAGTTGCA; GCCAAATGTGGACTATCCCCTGAGAAGGTGCGAATCATAAACATGTACAAGGAAATTGAT; CAAACACCCTACAAACAAGAGATCAATGCCAAGAACCTAATCCAGTGTTGGAGAGAATGT; ATGGCCATGTCTTCCTACTCCTTGAGGAAAGTTGCTGTGGAAAAGTTCAATGCAGAGAAT; TATTGGAAGAAGAAAGGACTGGCCATGGTCCCCCTGAAGTTTCCTGTTGGCCTTGGCTCA; CGTGCTGCTGGTCAGGCTGCTGCCTTGGTTCACATTTATCTTGATGGCTCTGTGCTGGTC; ACTCACGGTGGAATTGAAATGGGGCAGGGGGTCCACACTAAAATGATTCAGGTGGTCAGC; CGTGAATTAAGAATGCCAATGTCGAATGTCCACCTGCGTGGAACAAGCACAGAAACTGTC; CCTAATGCAAATATCTCTGGAGGTTCTGTGGTGGCAGATCTCAACGGTTTGGCAGTAAAG; GATGCCTGTCAAACTCTTCTAAAACGCCTCGAACCCATCATCAGCAAGAATCCTAAAGGA; ACTTGGAAAGACTGGGCACAGACTGCTTTTGATGAAAGCATTAACCTTTCAGCTGTTGGA; TACTTCAGAGGTTATGAGTCAGACATGAACTGGGAGAAAGGCGAAGGCCAGCCCTTCGAA; TACTTTGTTTATGGAGCTGCCTGTTCCGAGGTTGAAATAGACTGCCTGACGGGGGATCAT; AAGAACATCAGAACAGACATTGTCATGGATGTTGGCTGCAGTATAAATCCAGCCATTGAC; ATAGGCCAGATTGAAGGTGCATTTATTCAAGGCATGGGACTTTATACAATAGAGGAACTG; AATTATTCTCCCCAGGGCATTCTGCACACTCGTGGTCCAGACCAATATAAAATCCCTGCC; ATCTGTGACATGCCCACGGAGTTGCACATTGCTTTGTTGCCTCCTTCTCAAAACTCAAAT; ACTCTTTATTCATCTAAGGGTCTGGGAGAGTCGGGGGTGTTCCTGGGGTGTTCCGTGTTT; TTCGCTATCCATGACGCAGTGAGTGCAGCACGACAGGAGAGAGGCCTGCATGGACCCTTG; ACCCTTAATAGTCCACTGACCCCGGAGAAGATTAGGATGGCCTGTGAAGACAAGTTCACA; AAAATGATTCCGAGAGATGAACCTGGATCCTACGTTCCTTGGAATGTACCCATCTGA; ; Clone variation with respect to NM_001159.3;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001159 unedited; GGGTTTGCGNATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGTC; TTCATCTTCGCCGGATGATTTCCGCCCACATAGAGGGCGCCAGTGACGCCCACACACGTG; CTGGTGTCCCGGGAAGAGTTCCTGGCAAAGAGCTCAGGAACGTTGGATCTTAATCAAGGC; TTTCTCCGTCGGGGTGGATGGGTTGGACTTTAGGCTCCAGCAAGCCCCGCCCCACTCGGC; GGGTCGGTGCCGCCGGGTCCCAGGTGCCCGCTACTTCCCAGAACCTCCGCCTCCCGCTCC; GGGCCCTCGAACCAGCGCGGACACCACAATGGACCGGGCGTCCGAGCTGCTCTTCTACGT; GAACGGCCGCAAGGTGATAGAAAAAAATGTCGATCCTGAAACAATGCTGTTGCCTTATTT; GAGGAAGAAGCTTCGACTCACAGGAACTAAGTATGGCTGTGGAGGAGGAGGCTGTGGTGC; TTGTACAGTGATGATATCACGATACAACCCCATCACCAAGAGGATAAGGCATCACCCAGC; CAATGCCTGTCTGATTCCCATCTGTTCTCTGTATGGTGCTGCCGTCACCACAGTAGAAGG; CATAGGAAGCACCCACACCAGAATTCATCCTGTTCAGGAGAGGATTGCCAAGTGTCATGG; CACCCAGTGTGGCTTCTGCACACCTGGGATGGTGATGTCCATCTACACGCTGCTCAGGAA; CCACCCAGAGCCCACTCTGGATCAGTTAACTGATGCCCTTGGTGTAACCTGTGCCGTTGC; ACTGGATCAGGCCCATAATTGATGCATGCAAGACTTTCTGTNAAACTTCGGGCTGCTGTC; AAAGTAAAGAAAAGGGGCTTTGCTGTTTGGATCAAGGATCCAATGGATTGCCAGAATTTG; AGGAAGGAAGTAAGACAAGTCCATACTCT;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001159 unedited; CTTGGACGCGGCCGCAATCTAGNAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTCATATT; AGAAATGAAATTATTTAAAAAATTGCCTTTCACTATATGGTATAATTTCTGTTGGGGGAT; AGAAGCCAAGTAGGAGTCACATGCAAGTCATCACCTATTCCATTTAGCTGGATGGATTGA; AGAGACAGAGTAATGACGAATATCACCCTAGAGGAAACCAATTAGTGTTTATAACATTGA; AAATGATTTATAGATTGCTTAAGCATATCTATCAAATCTAAATGGAATACTTTAAATCAG; CTCCATAGAAAAGCAACACTGTGGGATGATTTCTGAACTGTGGAAACTCTGTCTTTCAAA; TCTAGCATCTTCCAGCACAGAGATAGGACAGATTGCCATCTGGGAAGAGGCACTCTGTTT; TCTCCAAAAGTTTGCATTTGATTCAGATGGGTACATTCCAAGGAACGTAGGATCCAGGTT; CATCTCTCGGAATAATTCTTGTGAACTTGTCTTCACAGGCCATCCTAATCTTCTCCGGGG; TCAGTGGACTATTAAGGGTCAAGGGTCCATGCAGGCCTTTTTCCCTGACCGGCTGCATTC; ACTGCGTCATGGATAGTCAAAAACACGGAACACTCTACGAACACCCTCGCCTTTCCCATA; CTCTCAAATTAACAAGAATTTTTCCGAGTTCTTCCACGCGTGTCTCATACTCAGTTCTCC; ACTCCCATGGTACCCCCCCTTCTGGTTCGCCATTTTCTTTTTGTTCTGGGCCCGTAAGCG; GTTCCCACTGCGTCATTCGTTCCCTTAATCCCATCCCCCCCGCCGGTTTTACCGCCCATC; TCCTTTCTTCACATTCCCATCTCTATTCGCTCTCTACTCCCCCCTCCTTTCTCACCCTCC; CCACCCACTGTATTATTATACTCTCCTTCTCCTCCCCCTCCTTCCACTCCCACTCACCTA; TTTTTACCCCATTCCACGCACACTCTATCCCTTATACCTACTCCCA;
• Restriction Sites: NotI-NotI
• ACCN: NM_001159
• Insert Size: 4640 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001159.3, NP_001150.3
• RefSeq Size: 4949 bp
• RefSeq ORF: 4017 bp
• Locus ID: 316
• UniProt ID: Q06278
• Cytogenetics: 2q33.1
• Domains: Ald_Xan_dh_C, CO_deh_flav_C, FAD_binding_5, fer2, fer2_2
• Protein Families: Druggable Genome
• Protein Pathways: Drug metabolism - cytochrome P450, leucine and isoleucine degradation, Metabolic pathways, Nicotinate and nicotinamide metabolism, Tryptophan metabolism, Tyrosine metabolism, Valine, Vitamin B6 metabolism
• Summary: Aldehyde oxidase produces hydrogen peroxide and, under certain conditions, can catalyze the formation of superoxide. Aldehyde oxidase is a candidate gene for amyotrophic lateral sclerosis. [provided by RefSeq, Jul 2008]