Tripeptidyl peptidase II (TPP2) (NM_003291) Human Untagged Clone

SKU SC108509

TPP2 (untagged)-Human tripeptidyl peptidase II (TPP2)

Product Data

• Type: Human Untagged Clone
• Target Symbol: Tripeptidyl peptidase II
• Synonyms: IMD78; TPP-2; TPP-II; TPPII
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC108509 sequence for NM_003291 edited (data generated by NextGen Sequencing); ATGGCCACCGCTGCGACTGAGGAGCCCTTCCCTTTTCACGGTCTCCTGCCGAAGAAGGAG; ACCGGAGCCGCCTCCTTCCTCTGCCGCTACCCGGAGTATGATGGGCGGGGGGTGCTCATC; GCAGTCCTGGACACGGGGGTCGACCCGGGGGCTCCGGGCATGCAGGTTACAACTGATGGA; AAACCAAAAATCGTTGATATCATTGATACAACAGGAAGTGGCGATGTGAATACTGCTACA; GAAGTAGAGCCAAAGGATGGTGAGATTGTTGGCCTTTCAGGAAGAGTGCTTAAGATTCCT; GCAAGCTGGACAAATCCCTCAGGCAAATATCATATTGGCATAAAAAATGGCTATGACTTC; TATCCTAAGGCACTCAAGGAAAGGATACAGAAAGAACGGAAGGAAAAAATCTGGGACCCT; GTTCACAGAGTGGCCCTTGCAGAAGCCTGTAGAAAACAGGAAGAATTTGATGTTGCCAAC; AACGGCTCTTCTCAAGCAAATAAACTAATCAAGGAGGAACTTCAAAGTCAAGTGGAATTG; CTAAATTCTTTTGAGAAGAAATACAGCGATCCTGGCCCTGTATATGACTGCTTGGTATGG; CATGATGGCGAAGTCTGGAGAGCCTGCATTGATTCTAATGAAGATGGGGACTTGAGTAAA; TCTACCGTGTTGAGAAACTACAAAGAAGCCCAAGAATATGGCTCTTTTGGCACAGCTGAG; ATGTTGAATTACTCCGTTAATATATACGATGATGGAAACCTGCTCTCCATTGTGACCAGT; GGAGGAGCTCATGGGACACATGTAGCTAGTATAGCTGCTGGACACTTTCCAGAAGAACCT; GAACGGAATGGGGTAGCTCCTGGTGCTCAAATTCTTTCCATCAAGATTGGTGATACAAGA; CTAAGCACAATGGAAACAGGCACAGGCCTCATAAGAGCTATGATAGAAGTTATAAATCAT; AAGTGTGATCTTGTCAACTACAGTTACGGAGAAGCAACTCACTGGCCAAATTCTGGGAGA; ATTTGTGAAGTAATTAATGAAGCAGTATGGAAGCATAATATAATTTATGTTTCAAGTGCT; GGAAATAATGGTCCATGCCTGTCTACAGTTGGTTGTCCAGGTGGAACTACATCAAGTGTG; ATAGGTGTTGGTGCTTATGTTTCTCCTGATATGATGGTTGCTGAGTATTCACTGAGAGAG; AAATTACCTGCAAATCAATATACTTGGTCTTCTAGAGGACCTAGTGCTGACGGGGCCCTT; GGTGTGAGTATCAGTGCGCCAGGAGGAGCCATTGCTTCTGTTCCTAACTGGACACTGAGA; GGGACGCAGCTGATGAATGGAACATCTATGTCTTCCCCCAATGCATGTGGAGGCATTGCC; CTGATCCTTTCAGGTCTGAAAGCTAATAACATTGACTACACAGTTCATTCAGTCAGAAGA; GCTCTAGAAAACACTGCAGTGAAGGCTGACAATATAGAAGTATTTGCTCAAGGACATGGT; ATTATTCAGGTTGATAAAGCCTATGACTACCTCGTTCAGAATACATCATTTGCTAATAAA; TTAGGTTTTACTGTTACTGTTGGAAATAACCGTGGCATCTACCTCCGAGATCCTGTTCAG; GTGGCTGCACCTTCAGATCATGGCGTTGGCATTGAACCTGTATTTCCGGAGAACACAGAA; AACTCTGAAAAAATATCCCTTCAGCTTCATTTAGCTCTGACTTCAAATTCATCTTGGGTT; CAGTGTCCCAGCCATTTGGAACTCATGAATCAATGTAGACACATAAACATACGTGTGGAT; CCCAGGGGCTTAAGAGAAGGATTGCATTATACAGAGGTATGTGGCTATGATATAGCATCC; CCTAACGCAGGTCCGCTCTTCAGAGTTCCGATCACTGCAGTTATAGCAGCAAAAGTAAAT; GAATCATCACATTATGATCTAGCCTTTACAGATGTACACTTTAAACCTGGTCAAATTCGA; AGGCATTTTATTGAGGTTCCTGAGGGTGCAACATGGGCTGAAGTGACAGTGTGTTCGTGT; TCTTCTGAGGTGTCAGCAAAGTTTGTTCTACATGCAGTCCAGCTTGTGAAGCAAAGAGCA; TATCGAAGCCATGAATTCTATAAGTTTTGTTCTCTTCCAGAGAAAGGAACACTGACTGAA; GCTTTTCCTGTCCTAGGTGGAAAAGCAATTGAATTTTGCATTGCTCGTTGGTGGGCAAGT; CTCAGTGATGTCAACATTGATTATACCATTTCTTTCCATGGGATAGTGTGTACTGCTCCT; CAGTTAAACATTCATGCATCGGAAGGAATCAACCGCTTTGATGTTCAGTCCTCCTTGAAA; TACGAAGATCTGGCTCCCTGCATAACTTTGAAGAACTGGGTCCAAACACTGCGCCCAGTG; AGTGCAAAAACAAAACCTTTAGGATCAAGAGATGTTTTGCCAAATAACCGTCAACTTTAT; GAGATGGTCCTGACATATAACTTTCATCAACCCAAGAGTGGGGAAGTAACTCCAAGCTGC; CCACTACTTTGTGAACTATTATATGAATCTGAATTTGACAGCCAACTGTGGATTATTTTT; GACCAGAACAAAAGACAGATGGGTTCAGGCGATGCCTATCCACATCAGTATTCTTTGAAA; CTGGAGAAAGGAGATTATACAATTCGACTACAGATTCGCCATGAGCAAATCAGTGATTTG; GAACGCCTTAAAGACCTTCCATTTATTGTTTCTCATAGATTGTCTAATACCTTGAGCTTA; GATATTCATGAAAATCATAGTTTTGCACTTCTAGGGAAGAAGAAATCAAGCAATTTGACA; TTACCACCCAAATATAACCAGCCATTCTTTGTTACTTCCTTACCTGATGATAAAATACCT; AAAGGGGCAGGACCTGGATGCTATCTTGCAGGATCCTTAACATTGTCAAAGACTGAACTA; GGAAAGAAAGCTGATGTAATCCCTGTTCATTACTACTTAATACCTCCACCAACAAAGACT; AAGAATGGCAGCAAAGATAAGGAAAAAGATTCAGAAAAAGAGAAAGATTTAAAAGAAGAG; TTTACTGAAGCATTACGAGATCTTAAAATTCAGTGGATGACAAAGCTGGATTCTAGTGAC; ATTTATAACGAATTGAAAGAAACATATCCTAATTATCTTCCTCTGTACGTTGCACGACTT; CATCAATTGGATGCTGAAAAGGAACGAATGAAAAGACTTAATGAAATTGTTGATGCGGCA; AATGCTGTTATTTCTCATATAGATCAAACAGCCCTAGCAGTTTATATTGCAATGAAGACT; GATCCCAGGCCTGATGCAGCTACTATAAAAAATGACATGGACAAACAAAAATCCACCCTC; GTAGATGCCCTTTGTAGGAAAGGTTGTGCCCTGGCAGACCATCTTCTTCACACCCAGGCT; CAAGACGGAGCCATTTCCACTGATGCAGAAGGAAAGGAGGAGGAAGGAGAAAGTCCTTTG; GATTCTCTGGCAGAAACATTTTGGGAAACTACTAAATGGACTGATCTCTTTGACAATAAG; GTTTTGACATTTGCATATAAACATGCATTAGTAAATAAAATGTATGGGAGAGGCCTTAAA; TTTGCAACTAAACTTGTGGAAGAAAAACCAACAAAAGAAAACTGGAAAAATTGTATTCAA; CTGATGAAGTTACTTGGATGGACCCATTGTGCATCTTTTACTGAAAACTGGCTCCCCATC; ATGTATCCTCCCGATTATTGCGTATTCTAA; ; Clone variation with respect to NM_003291.2;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003291 unedited; GTTTTTNGGNAATTATGTNAATACGCACTTCACTNTAAGGGNCGCGCCGCGNAATTCGGC; ACCAGCCATGGCCACCGCTGCGACTGAGGAGCCCTTCCCTTTTCACGGTCTCCTGGCGAA; GAAGGAGACCGGAGCCGCCTCCTTCCTCTGCCGCTACCCGGAGCATGATGGGCGGGGGGC; GCTCATCGCAGTCCTGGACACGGGGGTCGACCCGGGCGCTCCGGGCATGCAGGCTACAAC; TGATGGAAAACCAAAAATCGCCGATATCATTGATACAACAGGAAGCGGCGATGCGAATAC; TGCTACAGAAGTATAGCCAAAGGATGGTGAGATTGTTGGCCTTTCAGGAAGAGTGCTTAA; GATTCCTGCAAGCTGGACAAATCCCTCAGGCAAATATCATATTGCCATAAAAAATGGCTA; TGACTTCTATCCTAAGGCACTCAAGGAAAGGATACAGAAAGAACGGAAGGAAAAAACCTG; GGACCCTGTTCACCAGAGTGGCCCTTGCACAAGCCTGTAGAAAACAGGAAGAATTCGATG; CTGCCAACAACCGGCTCTTCTCAAGCCACTAAACTAACCCCGGAGGAACTTCAAAGCCAA; GTGGAACTGCTAAATTCTTTTGAGAAGAAATACAGCGATCCTGGCCCTGTATATGACTGC; TTGGCATGGCATGACGGCGAAGTCTGCAGAGCCTTGCTTGTATCTAATGAAGATGGGCAC; TTGAGTAAACCTACCGTGTTGACGAACCACCCAAGAGCCCAAGTATATCGGCTCTTTTTG; TCACAGTTGAAATGGTGAATTACTCCGCTCATATATACGATGATCGTAACCCTGCTCTCC; ATTGCGACCAACGCGAGGAGCCTATGCCACCCTCGCACTCACTATAGCCTGCTCGACACT; TCCCACACAACCTGAACGAAATGCGGGACCTCCTGCGCCCAATTCTTTCATCAAAATCGT; GA;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003291 unedited; NCCTATATATGANACCGCGGCCGCAATCTAGNATCGAGTTTTTTTTTTTTTTTTTTTTTT; TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTAAAAAACAGGGCTTTTTAAAAACCAGCCCG; GGATAGGGGAGGAAAACATGCTTTAAACTAAAAAGGCCACAAATTTGTTTTTATCCCCAT; TCACTATAAAACTTCCTTTTTTAAAATTAAAAGGCTGGTTCCCTTTTTTAAAATCCCCAA; TAATCGGGGGGATCCATGAGGGGGACCCATTTTTAAATAAAAAATGCCCAAGGGGCCCAT; CCAAGAAACTTCATAAGTGGAATACAATTTTCCCAGTTTTTTTTGGGGGGGTTTTCTTCC; ACAAGTTAAGTGGCAATTTTAAGGCCCCCCCCCTCCATTTTTTTAACTAAGGCATGGTTA; TACGCAAAGGTACAAACCTTTTTGGCCAAGAAATACCCCCCTTGACGAGTCCCCCCAAAG; GTGTCGTGCAAAAAATCACAAGGCCCTTTTCCTCCTCCCCGTTTTTCTCTTGCATAGCGG; GAACGGGCTCCCCCTTAGCCCGCGGCTGCTAAAAATACGGCCTCACTTCGCACCCTCCCT; TCCAGCAGGGAGCATCACTCGAGGCGGTCTTATGAGTATCGCGATATTCGTCTCTCCTCA; TGTCTCACCTCCTCGCTCCCGCCCTCCTTGCACCTCTTAGGTCGCCGCCCCTCTCCCATA; TTCGTACCGAACCCGCTCGGTGCGTCGAGCTCTCCGATCCCCGCGCTCGCTGCGAGCTCC; CTCACCCGTACCGCGTATCTCCGCCGTTTCCGCTCTAGCCCGGCCCCTCGCGACCCAAAC; TGCACACCGTCCGCCCCTCTCACCACATCTTTCCTCTTCTCGCCAGACCTATACGATTTA; CCTGTACTTTATATATCCGCGCCACCGATTCCCACCCCCCTACCG;
• Restriction Sites: NotI-NotI
• ACCN: NM_003291
• Insert Size: 4100 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_003291.1, NP_003282.1
• RefSeq Size: 4626 bp
• RefSeq ORF: 3750 bp
• Locus ID: 7174
• UniProt ID: P29144
• Cytogenetics: 13q33.1
• Domains: Peptidase_S8
• Protein Families: Druggable Genome, Protease
• Summary: This gene encodes a mammalian peptidase that, at neutral pH, removes tripeptides from the N terminus of longer peptides. The protein has a specialized function that is essential for some MHC class I antigen presentation. The protein is a high molecular mass serine exopeptidase; the amino acid sequence surrounding the serine residue at the active site is similar to the peptidases of the subtilisin class rather than the trypsin class. [provided by RefSeq, Jul 2008]; Transcript Variant: This variant (1) represents the shortest transcript and encodes the shortest, but most predominant, isoform (1).