TSPYL5 (NM_033512) Human Untagged Clone

SKU SC107059

TSPYL5 (untagged)-Human TSPY-like 5 (TSPYL5)

Product Data

• Type: Human Untagged Clone
• Target Symbol: TSPYL5
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC107059 sequence for NM_033512 edited (data generated by NextGen Sequencing); ATGAGCGGCCGAAGTCGGGGTCGAAAGTCCTCCCGCGCCAAAAACCGGGGCAAAGGCCGC; GCCAAAGCCCGAGTCCGCCCTGCTCCAGACGACGCCCCGCGCGACCCGGACCCTTCACAG; TACCAGAGTCTCGGGGAAGACACCCAGGCGGCACAGGTGCAGGCTGGCGCGGGGTGGGGT; GGCCTGGAAGCCGCTGCGTCCGCGCAGCTCCTCCGGCTCGGGGAGGAGGCCGCCTGCCGG; CTCCCCCTGGACTGTGGCCTCGCGCTGCGGGCCCGAGCTGCGGGGGACCACGGGCAGGCC; GCGGCCAGGCCCGGCCCGGGGAAGGCCGCATCTCTCTCGGAGCGCCTGGCCGCAGACACT; GTCTTCGTGGGAACAGCGGGAACCGTGGGAAGGCCGAAAAATGCCCCCCGCGTTGGAAAC; CGGCGTGGCCCTGCCGGGAAGAAGGCCCCAGAAACCTGTAGCACCGCGGGGAGGGGGCCT; CAGGTCATAGCTGGTGGGAGGCAGAAGAAAGGGGCGGCAGGGGAGAATACCTCGGTGTCA; GCTGGGGAGGAAAAGAAGGAAGAGAGGGATGCAGGGTCGGGGCCCCCAGCGACGGAAGGC; AGCATGGATACGCTGGAGAACGTGCAGCTGAAGCTGGAGAACATGAACGCCCAGGCGGAC; AGGGCCTACCTTCGGCTCTCCAGGAAGTTTGGGCAGTTGCGACTGCAGCACTTGGAGCGC; AGGAACCACCTCATCCAAAATATCCCGGGCTTCTGGGGGCAAGCATTTCAGAACCATCCC; CAGCTAGCATCCTTTCTGAATAGCCAAGAGAAAGAGGTACTGAGCTACTTAAACAGCTTG; GAAGTGGAAGAGCTCGGCCTTGCCAGATTGGGCTACAAAATCAAGTTCTACTTCGATCGC; AACCCGTATTTCCAAAATAAGGTGCTCATCAAGGAATATGGGTGTGGTCCTTCTGGCCAG; GTGGTGTCTCGTTCTACTCCAATCCAGTGGCTCCCAGGGCATGATCTCCAGTCCCTAAGC; CAGGGAAACCCAGAAAACAACCGTAGTTTCTTTGGGTGGTTTTCAAACCACAGCTCCATT; GAGTCTGACAAGATTGTGGAGATAATCAACGAAGAATTGTGGCCCAATCCCTTGCAGTTC; TACCTTTTGAGTGAAGGGGCTCGTGTAGAGAAAGGAAAGGAAAAAGAAGGCAGGCAAGGT; CCAGGAAAGCAGCCAATGGAGACTACTCAGCCTGGGGTGAGCCAATCCAACTGA; ; Clone variation with respect to NM_033512.2; 87 g=>a
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_033512 unedited; ACGACTCACTATAGGGCGGCCGCGAATTCGCACGAGGGTGACGTCGGCGGTTGCCGTGGA; GAGACCCGCTCGGTCCCGACCGAGAGCTGGCGTCAGGAGCCGCAGGGTCACAGCGTGTCT; TTGAAGCTGCCTCCGCCGCCACCATGAGCGGCCGAAGTCGGGGTCGAAAGTCCTCCCGCG; CCAAAAACCGGGGCAAAGGCCGCGCCAAAGCCCGAGTCCGCCCTGCTCCAGACGACGCCC; CGCGCGACCCGGACCCTTCACAGTACCAGAGTCTCGGGGAAGACACCCAGGCGGCACAGG; TGCAGGCTGGCGCGGGGTGGGGTGGCCTGGAAGCCGCTGCGTCCGCGCAGCTCCTCCGGC; TCGGGGAGGAGGCCGCCTGCCGGCTCCCCCTGGACTGTGGCCTCGCGCTGCGGGCCCGAG; CTGCGGGGGACCACGGGCAGGCCGCGGCCAGGCCCGGCCCGGGGAAGGCCGCATCTCTCT; CGGAGCGCCTGGCCGCAGACACTGTCTTCGTGGGAACAGCGGGAACCGTGGGAAGGCCGA; AAAATGCCCCCCGCGTTGGAAACCGGCGTGGCCCTGCCGGGAAGAAGGCCCCAGANACCT; GTAGCACCCGCGGGGGAGGGGGGCCTCAGGTCANNTAGCTGGTGGGAGGCANAAAGAAGG; GGGCGGCAGGGGAAGATACCCTCGGTGTCAGCTGGGGAGGAAAAGAAGGAAGAGAGGATG; CCAGGGTCGGGCCCCCCACGACGGAAGGCAGCATGGATACGCTGGAAAACGTGCAGCTGA; AGCTGGAGAACATGAACGCCCAGGCGGACAGGGCCTACCTTTGGTCTCCAAGAAATTTGG; GCCATTTTGGACTGGACCACTGGGACGGCAGGACCACCTCATCCAAAATCCCGGGCTTTT; GGGGGGACAGCTTTTAGACCCTCCCAGCTAGCATTCTTTTGAATGCAAAAAAAAGGGTCC; GGGCCTCTTACGTTA;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_033512 unedited; ACTATGGAACCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTT; TTTTTTTTTTTAACAGAGATACAGGTTTTTATTTTTCCATCATGCATGCAAACTTACAAC; TATTTATACTGTTTAAAAACACAGAAATAATTGCGTTATTAACAGGGTGTCAAATTACCA; AGTAGAACAACCAGTTACTAATTATTTTGGGGAGGTTATTTTCACAGAACACAGCAACAA; TTTCCAAATTATTCTTCCAAAACCAGAGTTATGAGACCAGTACAAGCTGATAACAATGCT; AATGGTCACACAAGTTTCCATGTTACACAGAAAAAAAGATTGACATTCTGGTGAAGGGTC; TCAAGTACCTTACCATATCAAAATTTTTGAAAGAGTTTTACAACAGAACAGTCTCTCTCT; TGTTTTGTAGATGCAAGGGAAAGGAAGCATCCCTCTCATTTCTTTTTGAGACTCCTTGTT; AATTCTTAAAACACATTTCTAAGGCCCATCTCTGGAACTTCATTAGTTAACATTAAAAGC; AAAAAGCAGACCTGATGTGATTATGATAGTGCACCCCATCACTATCACCATCAAAAGAGA; CTACCAATCTCCCAAAGTAGTCACGGTTGCATTGGCATAGTGTCTTGGATTTTCAATAAA; CAATACCGGTGAAAAGAGAGAGATACCGATGAAACCAGGTTGACCATAGCTGATAAGTGA; TGCAGCTAGGTGATGGACACATGGGGTCCAAGGACCATCCTCTCCACTTCTGTGCATGTC; TGAAAATGTCCNTAACACAGAGCAAAANAAAAAAAATATAACAAAAAACAAAAAAGCCGA; CTTGCACATCTGTATCTTCCCATTAGACTAAAATGGGGAAAGTCGNTAGACTTTAAGGNC; AAAATGTGCAGCATATAGCATTCTTCTGCATGTACAAAGCCCCACCTAGGAACAAAAAA;
• Restriction Sites: NotI-NotI
• ACCN: NM_033512
• Insert Size: 4600 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_033512.2, NP_277047.2
• RefSeq Size: 4478 bp
• RefSeq ORF: 1254 bp
• Locus ID: 85453
• UniProt ID: Q86VY4
• Cytogenetics: 8q22.1
• Summary: Involved in modulation of cell growth and cellular response to gamma radiation probably via regulation of the Akt signaling pathway. Involved in regulation of p53/TP53. Suppresses p53/TP53 protein levels and promotes its ubiquitination; the function is dependent on USP7 and independent on MDM2. Proposed to displace p53/TP53 from interaction with USP7.[UniProtKB/Swiss-Prot Function]