Syntaxin 12 (STX12) (NM_177424) Human Untagged Clone

SKU SC106981

STX12 (untagged)-Human syntaxin 12 (STX12)

Product Data

• Type: Human Untagged Clone
• Target Symbol: Syntaxin 12
• Synonyms: STX13; STX14
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_177424 edited; GAATTCGGCACGAGGCCCAGTTTCTCCGTCAGCCTGCGGGTCCCGGCTGGCGGCTGCTTC; CGGTAGGAGAGCGGTGTAGAGCGAGCAGGTCTCAGCTCCTCGTCATGTCATACGGTCCCT; TAGACATGTACCGGAACCCGGGGCCCTCGGGGCCCCAGCTCCGGGACTTCAGCAGCATCA; TCCAGACGTGCAGCGGCAACATCCAGCGGATCAGCCAAGCCACTGCTCAGATAAAGAATT; TGATGAGCCAGCTAGGAACTAAGCAGGACTCAAGCAAGCTACAGGAAAATCTGCAACAGT; TACAACACTCCACAAATCAGCTCGCCAAGGAAACAAATGAATTGCTGAAAGAATTAGGGT; CCTTGCCCCTTCCCTTATCTACTTCAGAACAGCGCCAGCAGAGACTTCAGAAGGAACGCC; TCATGAATGACTTCTCTGCAGCCTTAAACAATTTCCAGGCTGTGCAGAGAAGGGTATCTG; AAAAGGAAAAGGAGAGTATTGCCAGAGCAAGAGCTGGATCTCGTCTTTCTGCAGAAGAGA; GGCAAAGAGAGGAGCAGCTGGTCTCATTTGACAGCCATGAGGAGTGGAACCAGATGCAGA; GCCAGGAGGATGAGGTGGCCATCACTGAGCAGGATTTGGAACTTATTAAAGAAAGAGAAA; CGGCAATTCGGCAGCTGGAGGCTGACATTTTGGATGTCAATCAGATATTTAAAGATTTGG; CCATGATGATCCATGACCAGGGTGATCTGATTGATAGCATAGAAGCCAATGTGGAAAGCT; CAGAGGTGCACGTCGAAAGAGCCACTGAACAGTTACAGCGAGCTGCTTACTATCAGAAAA; AATCTCGCAAGAAGATGTGTATCCTGGTGCTTGTCCTGTCAGTGATTATTCTAATCTTGG; GACTTATTATCTGGCTAGTTTATAAAACGAAGTGATTGCCTCCGATCGTTCTCCCGCTGA; GCTGTTTTCAAGGGCAAGTGCTTGTTGAAGTCTTGCCAGAACAAACTGATCACAAGAAGA; CAGCATATATCAGAACGTCCTGTAATCATTTAGTTAGAAACTAACTACTAACTAGTCTTT; GGAATTCGTGACCTATGGAGACAGTAATTATCAATTTATTGATTCTATTGATTTCTCAAA; TTAGGAATTAACTTATGTGGATTTTGCTTCCTCTTGTATTCTGATTGCCCTTCATCCCAA; GTGTTTACTGAAAATTCCATTCTAGATATTCTTGTTTTGACAAATGACACTACAGTCTCG; TAATATTGTCTTTTATGTATATACAAAATTTACCTTTTTACTAGCATCTGAGATAGAGTT; ACTTTCTGGTACCCAGTATATTGGAGTCTGTCAGAAACTCTATAATAGGCCACCAGTTTT; TATTATTTAACATTTTTATTTGAATTTCTAAGAAGCCTATTCTCTATCTATTTTGAAAGA; TTTTGGCACTATATTTAATTGGAAGGTAAAATATTGTACATGTGATCCAGAGTAAATGAG; AAGTCTCTATCTGAGCTGGTCAGTTACTGGAGTACATGTTACTAATCTGGGTTTAAAGTT; TACTTCATTATCTGCTAGTGTCATCCACAGCAGTTCATCCTCATCCACACTAAGCCATCC; TGTTAGCTTTTAAAGGAAGTTAATTTAATTAACATTAATATACTCTATGGGCTCCCTCTC; CCACCTGTCTGCATAGAAAGGCAGAATTAGACATAGCATGCTTTGGAAAAGCAAATAGGA; ATTGTTGGGAATGATTTAATCTTGTTGTTGTTGTTGTTGTTGTTCACTTGTGGTTCTACA; TTCCTGGTGAATGATGAATGTTGCTGTCAAAGGGCTGCCCCCTACCTTATAAGGGTTGCT; GGGCATTTGAAGGCAGGAAGATTTTTAAAGATAGATTGAGGTTGGTTTAAAATTATTCCT; GTAAACCAACAATAAAGCAAAGAAGAGGTTCATTTTTGTAAATAACACTGGTTTCAAATA; GTGATGTTAGACTTAACCTAATTTATAAACAAGAGATTAATATCTCCATGCATAGTTTTA; GACAAAAAAAGATGTTTCAATAAAATTACTGTCTTGTAATATAAAAAAAAAAAAAAAAAA; CTCGAC;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_177424 unedited; GTTCAGATTTTGTAAACGACTTACTATAGGCGGCCGCGAATTCGCACGAGGCCCAGTTTC; TCCGTCAGCCTGCGGGTCCCGGCTGGCGGCTGCTTCCGGTAGGAGAGCGGTGTAGAGCGA; GCAGGTCTCAGCTCCTCGTCATGTCATACGGTCCCTTAGACATGTACCGGAACCCGGGGC; CCTCGGGGCCCCAGCTCCGGGACTTCAGCAGCATCATCCAGACGTGCAGCGGCAACATCC; AGCGGATCAGCCAAGCCACTGCTCAGATAAAGAATTTGATGAGCCAGCTAGGAACTAAGC; AGGACTCAAGCAAGCTACAGGAAAATCTGCAACAGTTACAACACTCCACAAATCAGCTCG; CCAAGGAAACAAATGAATTGCTGAAAGAATTAGGGTCCTTGCCCCTTCCCTTATCTACTT; CAGAACAGCGCCAGCAGAGACTTCAGAAGGAACGCCTCATGAATGACTTCTCTGCAGCCT; TAAACAATTTCCAGGCTGTGCAGAGAAGGGTATCTGAAAAGGAAAAGGAGAGTATTGCCA; GAGCAAGAGCTGGATCTCGTCTTTCTGCAGAAGAGAGGCAAAGAGAGGAGCAGCTGGTCT; CATTTGACAGCCATGAGGAGTGGAACCAGATGCAGAGCCAGGAGGATGAGGTGGCCATCA; CTGAGCAGGATTTGGAACTTATTAAAGAAAGAGAAACGGCAATTCGGCAGCTGGGAGCTG; ACATTTTGGATGTCAATCAGATATTTAAAGATTTGGCCATGATGATCCATTGACCAGGTG; ATCTGATTGATAGCATAGAAACCCAAGTGGAAAGCTCANAAGTGCCACGTCGAAAGAGGC; ACTGAACAGTTACAGCGAGCCTGCTACTATCAGAAAAAATCTCGCCAAGAGATGTGTATC; CTGGTGCTTGTCCCTGCAGTGATTATTC;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_177424 unedited; CCCCCCCGCCCCCCCCAAAATACCCCCCAANTTTACTTGNACCCGGCCGCAATCTAGATC; GAGTTTTTTTTTTTTTTTTTTATATTACAAGACAGTAATTTTATTGAAACATCTTTTTTT; GTCTAAAACTATGCATGGAGATATTAATCTCTTGTTTATAAATTAGGTTAAGTCTAACAT; CACTATTTGAAACCAGTGTTATTTACAAAAATGAACCTCTTCTTTGCTTTATTGTTGGTT; TACAGGAATAATTTTAAACCAACCTCAATCTATCTTTAAAAATCTTCCTGCCTTCAAATG; CCCAGCAACCCTTATAAGGTAGGGGGCAGCCCTTTGACAGCAACATTCATCATTCACCAG; GAATGTAGAACCACAAGTGAACAACAACAACAACAACAACAAGATTAAATCATTCCCAAC; AATTCCTATTTGCTTTTCCAAAGCATGCTATGTCTAATTCTGCCTTTCTATGCAGACAGG; TGGGAGAGGGAGCCCATAGAGTATATTAATGTTAATTAAATTAACTTCCTTTAAAAGCTA; ACAGGATGGCTTACTGTGGATGAGGATGAACTGCTGTGGATGACACTACCAGATAATGAA; GTAAACTTTAAACCCAGATTAGTAACATGTACTCCAGTAACTGACCAGCTCAAATAGAGA; CTTCTCATTTACTCTGGATCACATGTACAATATTTTACCTTTCCATTCAAATATAGTGCC; AAAATCTTTTCAAATAGAAAGAGAATACGGCTTTTACAAACTCCAAATAAAATGCTAACA; AATAAAACCTGTGGCCCTATTTTAGAGTTTCTGACTGACTCCAATATACTGGGGTCCCCC; AAGTAACTCCTATCTAAATGCCCCCCCACAGGTCAAATTTTGTATTTCCCTAAAAACACA; CTTTCCCAAACTCGCCGTCCCATCTGTCAN;
• Restriction Sites: NotI-NotI
• ACCN: NM_177424
• Insert Size: 2100 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_177424.1, NP_803173.1
• RefSeq Size: 2881 bp
• RefSeq ORF: 831 bp
• Locus ID: 23673
• UniProt ID: Q86Y82
• Cytogenetics: 1p35.3
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: SNARE interactions in vesicular transport
• Summary: SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. The SNARE complex containing STX6, STX12, VAMP4 and VTI1A mediates vesicle fusion (in vitro) (By similarity). Through complex formation with GRIP1, GRIA2 and NSG1 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting (By similarity).[UniProtKB/Swiss-Prot Function]