Snx17 (NM_001011981) Rat Untagged Clone

CAT#: RN215439

Snx17 (untagged ORF) - Rat sorting nexin 17 (Snx17), (10 ug)

Specifications

Product Data

• Type: Rat Untagged Clone
• Tag: Tag Free
• Symbol: Snx17
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >RN215439 representing NM_001011981
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCACTTTTCCATTCCTGAAACCGAGTCCCGCAGCGGGGACAGCGGCGGCTCCACCTACGTGGCCTATA
  ACATTCACGTGAATGGAGTCCTGCACTGTCGTGTGCGCTACAGCCAGCTCCTGGGGCTGCACGAGCAGCT
  TCGGAAGGAGTATGGGGCCAATGTGCTTCCTGCATTCCCCCCAAAGAAGCTTTTCTCTTTGACGCCTGCA
  GAGGTAGAACAGAGGAGGGAACAGTTAGAGAAGTACATGCAAGCTGTTCGGCAAGATCCATTGCTTGGGA
  GCAGTGAGACCTTTAATAGCTTTCTACGTCGGGCCCAACAGGAGACACAACAGGTCCCCACAGAGGAGGT
  TTCCTTGGAAGTGTTGCTCAGTGACGGACAGAAAGTTCTGGTCAATGTGCTAACTTCTGACCAGACGGAA
  GACGTCCTGGAGGCCGTGGCTGCAAAGCTGGATCTTCCAGATGACTTGATCGGATATTTTAGTCTCTTCC
  TTGTTCGAGAAAAAGAAGATGGCGCCTTTTCTTTTGTACGGAAGCTTCAGGAGTTTGAGCTGCCTTACGT
  ATCTGTCACCAGTCTTCGGAGTCAAGAGTATAAGATCGTGCTCAGAAAGAGTTACTGGGACTCTGCCTAT
  GACGACGATGTCATGGAGAACCGGGTTGGCCTGAACCTGCTTTATGCCCAGACGGTGTCAGACATCGAGC
  ATGGCTGGATCCTGGTCACCAAGGAGCAGCACCGACAGCTCAAATCTCTGCAAGAGAAGGTCTCCAAAAA
  GGAGTTCTTGCGGCTGGCCCAGACTCTGCGGCACTATGGCTATCTGCGCTTTGATGCCTGTGTGGCTGAC
  TTTCCGGAGAAGGACTGCCCTGTTGTGGTCAGTGCAGGCAACAGTGAGCTCAGTCTCCAGCTGCGACTCC
  CAGGCCAGCAGCTCCGTGAAGGCTCTTTCCGGGTCACCCGAATGCGGTGCTGGCGGGTCACCTCCTCTGT
  GCCACTCCCCAGTGGGGGTACAAGCACTCCAAGCCGGGGTCGGGGTGAGGTACGCCTGGAACTGGCTTTT
  GAATACCTCATGAGCAAGGACCGGCTACAGTGGGTCACCATCACCAGCCCACAGGCTATCATGATGAGCA
  TCTGCCTGCAGTCCATGGTAGATGAGCTGATGGTGAAGAAGTCTGGGGGCAGTATCAGGAAGATGCTGCG
  TCGGAGGGTGGGGGGCAACCTGAGACGTTCAGACAGCCAGCAAGCAGTGAAGTCCCCACCATTGCTCGAA
  TCACCAGATGCCAGCCGGGAATCCATGGTCAAACTCTCAAGTAAACTGAGTGCGGTGAGCTTGCGGGGAA
  TTGGCAGTCCCAGCACAGATGCCAGTGCCAGTGCCGTCCACGGCAATTTCGCCTTCGAGGGCATTGGAGA
  TGAGGATCTGTAA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001011981
• Insert Size: 1413 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001011981.1, NP_001011981.1
• RefSeq Size: 1944 bp
• RefSeq ORF: 1413 bp
• Locus ID: 298836
• UniProt ID: Q6AYS6
• Cytogenetics: 6q14
• Gene Summary: Critical regulator of endosomal recycling of numerous surface proteins, including integrins, signaling receptor and channels. Binds to NPxY sequences in the cytoplasmic tails of target cargos. Associates with retriever and CCC complexes to prevent lysosomal degradation and promote cell surface recycling of numerous cargos such as integrins ITGB1, ITGB5 and their associated alpha subunits. Also required for maintenance of normal cell surface levels of APP and LRP1. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)).[UniProtKB/Swiss-Prot Function]