Adam11 (NM_009613) Mouse Untagged Clone

CAT#: MC221476

Adam11 (untagged) - Mouse a disintegrin and metallopeptidase domain 11 (Adam11), transcript variant 2, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Adam11
• Synonyms: AW060611; Mdc
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC221476 representing NM_009613
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  CTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCCGGCGC
  GCCC
  
  ATGAGGCGGCTGCGGCGCTGGGCGATCGCGGCTCTGCTGCTGTTACCGCTTCTCCCCCCGCCCGGTCTTG
  GGGCCCTGGGTCCCAGAGGAGCTCTGCACTGGAGGAGCTCAGCCCATGTGGGGAGCCCAGAGAGTCCAGA
  GGGCTCTGAGGTCACAGAGCCCAGCCGGCTGGTAAGGCAGAGCTCCGGGGGAGAGGTCCGAAAGCCACAG
  TTGGACACCAGGGTCCGCCAGGATCCGCCCAGGGGGACGCCTGTGCACCTGGCCCAGGTGAGTTTCGTCA
  TCCCGGCCTTCGACTCAAACTTCACTCTGGACCTGGAGCTGAACCATCACCTCCTGTCCTCGCAGTATGT
  GGAGCGCCACTTCAGCCGGGAGGGAACAAGACAACACAGCACTGGGGCTGGAGACCACTGCTACTACCAT
  GGGAAACTCCGGGGCAACCCACAGTCCTTTGCTGCACTCTCTACATGCCAGGGGCTGCATGGGGTCTTCT
  CTGATGGCAACCTGACTTACATCGTAGAGCCTAAGGAGATAGCTGGGCCCTGGGGACCCCCACAGGGACC
  CCTTCCCCACCTCATTTACCGGACCCCTCTCCTCCCAGCCCCCCTTGGATGCAGGGAGCCAGGCTGCCTG
  TTTGCTGTCCCTGCCCAGTCTGCTCTCCCCAACTGGCCCAAGCTAAGAAGGAAAAGGCAGGTCCGCAGGG
  GCCACCCCACAGTGCACAGCGAGACCAAGTATGTGGAGTTGATTGTAATCAATGACCACCAGCTGTTTGA
  GCAGATGCGGCAGTCAGTGGTCCTCACCAGCAACTTTGCAAAATCTGTTGTGAACCTGGCAGATGTGATA
  TACAAGGAACAGCTCAACACAAGAATTGTTCTGGTTGCCATGGAAACGTGGGCAGATGGGGACAAGATCC
  AGGTGCAGGATGACCTACTGGAGACCCTGGCCCGGCTTATGGTCTACCGGCGGGAGGGTCTGCCTGAGCC
  CAGTGATGCCACCCACCTCTTCTCGGGTAGAACCTTCCAGAGCACCAGCAGCGGGGCGGCCTACGTGGGA
  GGCATCTGTTCACTGTCCCGGGGTGGAGGTGTGAACGAGTATGGCAACATGGGTGCCATGGCGGTGACCC
  TGGCCCAGACGCTAGGGCAGAACTTGGGCATGATGTGGAATAAGCACCGGAGCTCAGCAGGGGACTGCAA
  GTGTCCAGACATTTGGCTGGGCTGCATCATGGAGGACACTGGGTTCTATTTGCCCCGCAAGTTCTCGCGC
  TGCAGCATCGACGAATACAACCAGTTTCTGCAGGAGGGAGGCGGGAGCTGCCTGTTCAACAAGCCCCTCA
  AGCTTCTGGACCCTCCCGAGTGCGGAAACGGCTTCGTGGAGGCGGGAGAGGAGTGCGACTGCGGGTCGGT
  GCAGGAGTGCAGCCGAGCAGGGGGCAACTGCTGCAAAAAATGCACCTTGACGCACGACGCCATGTGCAGC
  GATGGGCTCTGTTGTCGCCGCTGCAAGTATGAGCCACGAGGTGTCTCCTGCCGAGAAGCGGTGAATGAGT
  GTGACATTGCAGAGACCTGCACCGGCGACTCAAGCCAGTGTCCCCCTAACCTTCACAAGCTGGACGGTTA
  CTACTGTGATCATGAGCAGGGTCGTTGCTATGGAGGCCGCTGTAAAACCCGGGACCGGCAGTGCCAAGCC
  CTATGGGGCCATGCGGCTGCGGATCGTTTCTGCTATGAGAAGCTGAACGTGGAGGGGACAGAGCGTGGAA
  ACTGTGGACGCAAGGGATCTGGTTGGGTCCAGTGCAGTAAGCAGGATGTGCTCTGTGGCTTCCTTCTGTG
  CGTCAACATCTCTGGAGCTCCGCGGCTAGGGGATCTGGGGGGCGACATCAGCAGTGTCACCTTCTACCAC
  CAGGGCAAGGAGTTGGACTGCAGGGGAGGCCACGTGCAGCTAGCTGATGGCTCGGACCTGAGCTATGTGG
  AGGACGGCACGGCCTGTGGGCCCAACATGTTGTGCCTAGATCACCGCTGCCTGCCAGCCTCTGCCTTCAA
  CTTCAGCACCTGCCCTGGAAGTGGAGAGCGAAGGATCTGCTCCCATCATGGGGTTTGCAGCAACGAGGGG
  AAGTGTATCTGTCAGCCAGACTGGACAGGCAAAGACTGCAGTATTCACAACCCACTGCCCACGTCCCCTC
  CCACTGGGGAGACTGAGAGATACAAAGGTCCCAGCGGTACCAACATCATCATTGGCTCCATCGCCGGGGC
  TGTCCTGGTCGCAGCCATCGTCCTGGGCGGCACGGGCTGGGGATTTAAAAACATCCGTCGTGGAAGGTCC
  GGAGGGGCCTAA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: AscI-MluI
• ACCN: NM_009613
• Insert Size: 2322 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_009613.3, NP_033743.2
• RefSeq Size: 4651 bp
• RefSeq ORF: 2322 bp
• Locus ID: 11488
• UniProt ID: Q9R1V4
• Cytogenetics: 11 66.48 cM
• Gene Summary: This gene encodes a member of a disintegrin and metalloprotease (ADAM) family of endoproteases that play important roles in various biological processes including cell signaling, adhesion and migration. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional protein. The protein encoded by this gene is believed to lack metalloproteinase activity due to the lack of a critical catalytic motif. Mice lacking the encoded protein exhibit defects in spatial learning, motor coordination and altered perception of pain. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing. [provided by RefSeq, May 2016]
  Transcript Variant: This variant (2) lacks an internal segment in the 3' region, as compared to variant 1. The encoded isoform (2) has a shorter and different C-terminus, as compared to isoform 1.