Abcg2 (NM_011920) Mouse Untagged Clone

SKU MC202064

Abcg2 (untagged) - Mouse ATP-binding cassette, sub-family G (WHITE), member 2 (Abcg2), (10ug)

Product Data

• Type: Mouse Untagged Clone
• Target Symbol: Abcg2
• Synonyms: ABC15; ABCP; AI428558; BCRP; Bcrp1; MXR; MXR1
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC053730 sequence for NM_011920; AAGAGGTAATCCGATATAAAAAGATCTCTCTGTCTGGATTTCCTCTTTTCCAATCTCCTTGCCAGATAAG AGGGGTTAGGTTGTCTTGAGTTGGAACCACATTTCTTTCTTGATTCAGGATAACCAGCTAACAGATATTC ACTACTGTCGTCCTGAAATTAACTGAGGATATTCATTAATTTCCTGGAAGCTAGATTTTTGAAAAGTCTT GATTTTGCCTGTCTCTTGAGGCAAAACTTAGCAACTTTGGGGATTGATAAATCTTCTGTCTTCCTGGTCC TCTCCCTGCTTTTTCTCAACTCCACTGCAAGCAAGAGTGGACATACTCTTAGGGTGGCTTTTGTGGCAGG CATGGATCCTAGCTGAACTCTTTCTCCAGTGTACAACATTGCTGCATCTCACTGAGGCCTGACGGTTCTC CTTTTGACACCTCATTACACATAGCAGAGAAAGGCATAAATCCTAAAGATGTCTTCCAGTAATGACCACG TGTTAGTACCAATGTCGCAGAGAAACAACAACGGCCTTCCTAGGACGAACTCCAGAGCCGTTAGGACGCT CGCAGAAGGAGATGTGTTGAGTTTTCATCACATCACCTATCGAGTGAAAGTAAAGAGTGGGTTTCTAGTC CGGAAAACAGTTGAGAAAGAAATACTATCAGATATCAATGGGATCATGAAACCTGGCCTTAATGCTATTC TGGGACCCACAGGCGGAGGCAAGTCTTCGTTGCTAGATGTCTTAGCAGCAAGGAAAGATCCAAAGGGATT ATCTGGAGATGTTTTGATAAATGGAGCACCTCAACCTGCCCACTTCAAATGCTGTTCAGGTTATGTGGTT CAAGATGACGTTGTGATGGGCACCCTGACAGTGAGAGAAAACTTACAGTTCTCAGCAGCTCTTCGACTTC CAACAACTATGAAGAATCATGAAAAAAATGAACGGATTAACACAATCATTAAAGAGTTAGGTCTGGAAAA AGTAGCAGATTCTAAGGTCGGAACTCAGTTTATCCGTGGCATCTCTGGAGGAGAAAGAAAAAGGACAAGC ATAGGGATGGAGCTGATCACTGACCCTTCCATCCTCTTCCTGGATGAGCCCACGACTGGTTTGGACTCAA GCACAGCGAATGCTGTCCTTTTGCTCCTGAAAAGGATGTCTAAACAGGGTCGAACAATCATCTTCTCCAT TCATCAGCCTCGGTATTCCATCTTTAAGCTGTTTGACAGCCTCACCTTACTGGCTTCCGGGAAACTCGTG TTCCATGGGCCAGCACAGAAGGCCTTGGAGTACTTTGCATCAGCAGGTTACCACTGTGAGCCCTACAACA ACCCTGCGGATTTTTTCCTTGATGTCATCAATGGAGATTCTTCTGCTGTGATGTTAAATAGAGAGGAACA AGACAATGAAGCAAACAAGACTGAAGAGCCTTCCAAGGGAGAGAAGCCAGTAATAGAAAATTTATCTGAG TTTTATATCAACTCTGCCATCTATGGAGAAACAAAAGCTGAATTAGATCAACTTCCAGGAGCTCAGGAAA AGAAAGGAACATCGGCCTTCAAAGAGCCAGTCTATGTTACCTCTTTCTGTCACCAGCTCCGATGGATTGC CAGGCGCTCATTTAAAAACTTGCTCGGGAACCCTCAAGCTTCTGTTGCTCAGTTAATTGTTACAGTCATA CTGGGGCTTATTATTGGTGCCATTTACTTTGATCTGAAATATGATGCCGCTGGAATGCAAAATAGAGCTG GAGTTTTGTTTTTCCTGACTACCAACCAGTGTTTTTCCAGTGTGTCAGCTGTGGAGCTGTTCGTAGTGGA GAAGAAACTCTTCATACATGAGTACATCAGTGGATATTACAGAGTGTCTTCTTACTTCTTTGGAAAGGTG ATGTCTGATTTACTCCCCATGAGGTTCTTGCCAAGTGTTATATTCACTTGTGTATTATACTTCATGTTAG GACTGAAGAAGACGGTGGATGCTTTTTTCATCATGATGTTTACCCTTATAATGGTGGCTTATACGGCCAG TTCCATGGCACTGGCCATAGCCACAGGCCAAAGTGTGGTGTCTGTAGCAACACTTCTCATGACAATCGCT TTTGTATTTATGATGCTCTTTTCTGGCCTCTTGGTGAATCTCAGAACCATTGGGCCTTGGCTGTCCTGGC TTCAGTACTTTAGCATTCCTCGATATGGCTTCACAGCTTTGCAGTATAATGAATTCTTGGGACAAGAGTT TTGTCCAGGATTCAATGTAACGGACAACAGCACTTGTGTTAACAGCTATGCAATATGTACTGGTAACGAG TACTTGATAAATCAGGGCATCGAACTGTCACCTTGGGGACTGTGGAAGAATCATGTGGCCCTGGCTTGTA TGATTATTATCTTCCTCACAATTGCCTACCTGAAATTGTTGTTTCTTAAAAAGTATTCTTAATTTCCCCC TTTAACGGACTATTAATTGTACTCCAATTAAATATGGGCACTTTGATTACCATAAAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_011920
• Insert Size: 1974 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: BC053730, AAH53730
• RefSeq Size: 2520 bp
• RefSeq ORF: 1974 bp
• Locus ID: 26357
• UniProt ID: Q7TMS5
• Cytogenetics: 6 27.82 cM
• Summary: The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, the human protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. This protein likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. [provided by RefSeq, Jul 2008]