Snx17 (NM_153680) Mouse Untagged Clone

SKU MC201773

Snx17 (untagged) - Mouse sorting nexin 17 (Snx17), (10ug)

Product Data

• Type: Mouse Untagged Clone
• Target Symbol: Snx17
• Synonyms: 5830447M19Rik; AI790646; b2b1625.1Clo; D5Ertd260e; mKIAA0064
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC026571 sequence for NM_153680; CCAAAATGGCGAGCTGGGCTGCGGAGACGCGCTGAGTGGCAGAGGCAAGCGAGCAGAGGCGCTGCGAACC TGGTAGTACGGAGCTCTGCCTTAGGGAACATGCACTTTTCCATTCCTGAAACGGAGTCCCGCAGTGGGGA CAGCGGCGGCTCCGCCTACGTGGCCTATAACATTCACGTGAATGGAGTCCTGCACTGTCGGGTGCGCTAC AGCCAGCTTCTGGGGCTGCACGAGCAGCTTCGGAAGGAGTATGGGGCCAACGTGGTTCCTGCATTCCCCC CAAAGAAGCTGTTCTCTTTGACCCCTGCAGAGGTGGAGCAGAGGAGAGAGCAGTTGGAGAAGTACATGCA AGCTGTTCGGCAAGACCCATTGCTTGGGAGCAGTGAGACTTTTAATAGCTTTCTACGTCGGGCCCAACAG GAGACCCAACAGGTGCCCACAGAGGAGGTTTCCTTGGAAGTGCTGCTCAGCAATGGACAGAAAGTTCTGG TAACTGTGCTAACTTCTGACCAGACAGAAGATGTCCTGGAGGCTGTGGCTGCAAAGCTGGATCTTCCAGA TGACTTGATCGGATATTTTAGTCTCTTCCTTGTTCGAGAAAAAGAAGATGGAGCCTTTTCTTTTGTACGG AAGCTGCAGGAGTTTGAACTGCCTTATGTATCTGTTACCAGTCTTCGGAGTCAAGAGTATAAGATTGTGC TCAGAAAGAGTTATTGGGACTCTGCCTATGACGACGATGTCATGGAGAACCGGGTTGGCCTGAACCTGCT TTATGCTCAGACGGTGTCAGACATTGAGCATGGCTGGATCCTGGTCACCAAAGAGCAGCACCGGCAGCTC AAATCTCTGCAAGAGAAGGTCTCCAAAAAGGAGTTCTTGCGGCTGGCCCAAACTCTGCGGCACTATGGCT ATCTGCGCTTTGATGCCTGTGTGGCTGACTTTCCAGAGAAGGATTGCCCTGTTGTGGTGAGCGCAGGCAA CAGTGAGCTCAGTCTCCAGCTGCGACTACCAGGCCAGCAACTCCGTGAAGGCTCTTTCCGTGTTACCCGA ATGCGATGCTGGCGGGTCACCTCCTCTGTGCCACTCCCTAGTGGGGGCACGAGCAGTCCAAGCCGGGGTC GGGGTGAGGTTCGCCTGGAACTGGCTTTTGAATACCTCATGAGCAAGGACCGGCTACAGTGGGTCACCAT CACCAGCCCACAGGCTATCATGATGAGCATCTGCCTGCAGTCCATGGTAGATGAGCTGATGGTGAAGAAA TCTGGGGGCAGTATCAGGAAGATGCTGCGCCGGCGGGTGGGGGGCACCCTGAGACGTTCAGACAGCCAGC AAGCAGTGAAGTCCCCACCATTGCTCGAGTCACCAGACGCCAGCCGGGAGTCCATGGTGAAACTCTCAAG TAAACTGAGTGCTGTGAGCTTGCGGGGGATTGGCAGTCCCAGCACAGATGCCAGTGCCAGTGCCGTCCAC GGCAATTTCGCCTTCGAGGGCATTGGAGATGAGGATCTGTAATCTCAGCTGCCTGGATGTCTGCCCTCTA CCTGAGAGGAGATTTATACACACTTGCCCTGTGCCTATGCTCCCACGTTAGGGGAGTCTCTTCCTATTCC CTCCCCACTTCTCCTTGTTCCTCTTGGCCAGGGGCCTCCTAACCATACCTTCCCTTTTCCTGGGCTGGCT ACACAAAAGATCACTGTCTCTTTTTTAGAGCTGGCCCTTGATGCCAAATTAGCATTTAGTATTTTGCACA AAGTCCAAGAGACTGTGGCTACTTGCCTCGGAGAGGAACTCTAACACTCCATGGGTTGTTTCTGGCTTTT GAGGAACTCCAGCACTCCATGGGTTGTTTCTGGCTTTTCAGGGCCTGGGCAAAGGGTGGGCAGAGGTCTG TGAATGGTCTGAGCAGCTCCCCATCATTAAACTCAGCCTGATTGCCGCCTAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_153680
• Insert Size: 1413 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: BC026571, AAH26571
• RefSeq Size: 1995 bp
• RefSeq ORF: 1413 bp
• Locus ID: 266781
• UniProt ID: Q8BVL3
• Cytogenetics: 5 B1
• Summary: Critical regulator of endosomal recycling of numerous surface proteins, including integrins, signaling receptor and channels (PubMed:12169628, PubMed:16052210). Binds to NPxY sequences in the cytoplasmic tails of target cargos (By similarity). Associates with retriever and CCC complexes to prevent lysosomal degradation and promote cell surface recycling of numerous cargos such as integrins ITGB1, ITGB5 and their associated alpha subunits (By similarity). Also required for maintenance of normal cell surface levels of APP and LRP1 (PubMed:16052210, PubMed:18276590). Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) (By similarity).[UniProtKB/Swiss-Prot Function]