Elmo2 (NM_207706) Mouse Untagged Clone

SKU MC201732

Elmo2 (untagged) - Mouse engulfment and cell motility 2, ced-12 homolog (C. elegans) (Elmo2), transcript variant 2, (10ug)

Product Data

• Type: Mouse Untagged Clone
• Target Symbol: Elmo2
• Synonyms: 1190002F24Rik; CED-12
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC023954 sequence for NM_207706; CCACGCGTCCGGACGCGGGCGCGGAGCTGGGCCTCGGCGGGTGCCGGGCAGCTGTGTCTTGAAGAAGGGC CCGCCGGGAACAATGCCGCCTCCGTCTGACATTGTCAAAGTGGCCATCGAGTGGCCAGGTGCTAACGCCC AGCTCCTTGAAATTGACCAGAAACGGCCGCTGGCATCCATCATCAAGGAGGTGTGCGATGGGTGGTCACT GCCGAACCCGGAGTACTACACCCTCCGCTATGCAGATGGGCCTCAGCTCTACGTCACGGAGCAGACCCGA AATGACATTAAGAACGGGACAATCTTACAACTGGCCGTCTCCCCGTCCCGGGCTGCACGCCAGCTGATGG AAAGGACCCAGTCATCTAGTATGGAGACCCGGCTGGATGCCATGAAGGAGTTGGCTAAGCTCTCAGCTGA CGTGACTTTCGCCACGGAGTTCATTAACATGGACGGCATCATTGTGCTGACGAGGCTCGTGGAGAGTGGG ACCAAGCTCCTGTCCCACTACAGTGAGATGCTGGCATTCACCCTGACTGCCTTCTTAGAGCTCATGGATC ATGGCATTGTCTCCTGGGACATGGTTTCAGTCACCTTTATTAAGCAGATTGCAGGGTACGTGAGCCAGCC CATGGTCGATGTGTCCATCCTCCAGCGGTCCCTGGCCATCCTAGAGAGCATGGTACTAAACAGCCAGAGC CTGTACCAGAAGATAGCGGAGGAGATCACCGTGGGACAGCTCATCTCCCACCTGCAGGTCTCCAACCAGG AGATCCAGACCTACGCCATTGCTCTGATTAACGCGCTGTTCCTGAAGGCCCCCGAAGACAAGAGACAGGA CAAGCACCTTAACCCTCTAGACCTGCCCGTCACTGACATGGCCAATGCCTTTGCACAGAAGCACCTTCGG TCCATAATCCTGAACCATGTGATCAGAGGGAATCGTCCAATCAAAACAGAGATGGCCCATCAGCTGTATG TCCTTCAGGTCTTGACCTTTAACCTTCTGGAAGAAAGAATGATGACCAAGATGGATCCCAATGACCAGGC TCAGAGAGACATTATATTTGAACTGAGGAGGATTGCCTTCGACGCAGAGTCTGACCCCAGCAACGTCCCC GGGAGTGGGACTGAAAAGCGCAAGGCCATGTATACCAAGGACTATAAAATGCTGGGCTTCACCAACCATA TCAACCCAGCCTTGGACTTCACCCAGACTCCTCCTGGAATGCTGGCGCTGGACAACATGCTGTACCTGGC TAAAGTCCACCAGGACACCTACATCCGGATCGTGCTGGAGAACAGCAGTCGGGAGGACAAACACGAGTGT CCGTTCGGCCGCAGTGCCATCGAGCTCACCAAGATGCTCTGTGAGATCCTGCAGGTCGGGGAGCTCCCTA ATGAAGGGCGCAATGACTACCACCCCATGTTCTTCACCCACGACCGAGCCTTCGAGGAACTCTTCGGGAT CTGCATCCAGCTGCTGAACAAGACCTGGAAGGAGATGAGGGCGACAGCCGAGGATTTCAACAAGGTTATG CAAGTTGTCCGAGAGCAGATCACCCGGGCTCTGCCCTCTAAACCCAACTCTTTGGATCAGTTCAAGAGTA AACTTCGTAGCCTGAGCTACTCAGAAATTCTGCGGTTGCGCCAGTCTGAGAGGATGAGCCAGGATGATTT CCAGTCCCCACCAATTGTGGAGCTTCGAGAGAAGATACAGCCTGAGATCCTGGAGCTGATCAAGCAACAG CGCCTCAACCGGCTATGCGAGGGCAGCAGCTTCCGGAAAATCGGGAACCGTCGTCGGCAAGAGAGGTTCT GGCACTGCCGCTTGGCACTGAACCACAAGGTTTTGCATTACGGTGACTTGGATGACAACCCTCAAGGGGA GGTGACATTCGAATCCCTGCAGGAGAAAATTCCTGTTGCAGATATTAAGGCCATTGTTACTGGAAAAGAC TGTCCTCACATGAAAGAGAAGAGTGCCCTGAAACAGAACAAGGAGGTGTTGGAATTGGCCTTCTCCATCC TGTATGATCCTGATGAGACACTGAATTTCATTGCTCCCAACAAGTATGAGTACTGCATCTGGATTGATGG ACTCAGCGCTCTCCTGGGGAAGGATATGTCCAGCGAGCTAACCAAGAGCGACTTGGACACGCTGCTGAGC ATGGAGATGAAGCTGCGGCTTCTGGACTTGGAGAACATTCAGATCCCCGAGGCGCCACCTCCGGTCCCCA AGGAGCCCAGCAGCTATGACTTCGTCTATCACTATGGCTGAGCGGGAAGGGACTGGGGCCCAGGAGAGAC ACTGGCAGCCCACGCCACTTGTACAAACTCTGTAGTGATTGTGGTAACTACTCCTCAGAGCCAGTGGGAC CCAGAGCTTCTCTCTGTCCCATCCACCAGGAGTCATGAAGTCAGGGCATGCTGCCCTCCTCAGCACCACA GAGCCTGGGTCGGGCTTGGAGGGGTGAACTCATGAGGCTCCTGCCTCCCGCTCTGCGTCACATCTGCATC TGGTACTGGACCTACTGACAGCCATCCCCTTTCCTTTCAAGTCTCCTCTCTGGTTTGTTGGAGAGCCCAT GTGGGCCAAAGCTGGTCCATGAAAGGCTGACCATGGGGGCAAGAGGCCTGGGGAGCTCGGTGAGAGCCTC GGAGTGACTGTCTTCAGGTGGCTCAGGCAAGAACAGGCCTTGAGCTCCTGCTTAATAGGTCTCTGAGGGC TCATCCCAGCCTCGTCCTGTGCCTCATGCTGCTGCCTCTGGGGTTTGGCCCTACCATGTCTAGTCTCTAG AGACACCCGTCTCTCTTGTCCTTGCAGGTATCAGGACAGGTAGTAATTTTGCCCCAAGCCCTCAGCCTCA TCCTGGCCAGGCAGAGGCCTCCAGCCTGAGTCCTGCTCTCTTAGGCTTTAGGAATGAACACTGCAGGGAA AGGCAGGCTGAGGCCTCTGGCTCCCCCTACCCCTCCAGTCCTCTCTCTTCCTTGCTGAGGCACAATATTC CCATGCCCCCTCAGTTACAGGCCCCTCCGTTTGCTTCCCTCCTGCCTCAGACAGGGGTGTTGCCTTCCCT TTCTCCCCTTCCTGGCGCTGTGGTTTGTGCCATTAGCCATGATTTCACAGCGGCTGGGGCCACAGCTGTG CCACGGCCTTCATTGGTGCTGCAGCACTGGAAGCCCACGCGCACAGCCTCTTTCCTTGGACGCATGTTAC CATGGTGGTATTCAGTACTGGTAGCCTGGCATGGTGGGTACTACCCAGTGAAGAGTGTACTATATATTTT CTTTACTATAGGCCATACTTATACAGACATGTATATATATTTATATAAGATCTTCCTATCTTAGGATAGA ATGTTTAAGGGAAAATAAAATCAAGAACAAAACTGTAGTGCTCTCAGTCATGAGCTGTGAGTGTAACCAG AGAGCAGCCAGGAGCTTCCTGTCAGTGATGTGTTTTCAATAAATACTCTTTCATGTAAAAAAAAAAAAAA A
• Restriction Sites: RsrII-NotI
• ACCN: NM_207706
• Insert Size: 2199 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: BC023954, AAH23954
• RefSeq Size: 3501 bp
• RefSeq ORF: 2199 bp
• Locus ID: 140579
• UniProt ID: Q8BHL5
• Cytogenetics: 2 H3
• Summary: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1 (By similarity).[UniProtKB/Swiss-Prot Function]; Transcript Variant: This variant (2) encodes the longest isoform (2).