Human PC1/3 (PCSK1) (NM_001177875) AAV Particle

SKU RC230447A1V

AAV ORF Particle, Serotype AAV-2, PCSK1 (Myc-DDK-tagged)-Human proprotein convertase subtilisin/kexin type 1 (PCSK1), transcript variant 2, (10ug), 250ul, 10^13 TU/mL

Product Data

• Tag: Myc-DDK
• Target Symbol: PCSK1
• Synonyms: BMIQ12; NEC1; PC1; PC3; SPC3
• Vector: pAAV-AC-Myc-DDK
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  >NM_001177875 ORF sequence, RC230447 may differ due to SNPs.; Blue=ORF Red=Cloning site Green=Tag(s); ; GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG; GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC; ATGGGGAAGGGATCTATTTCTTTCTTGTTCTTCAGCCAAATTGGTTCACTTGAAAATCACTACTTATTC; AAACATAAAAACCACCCCAGAAGGTCTCGAAGGAGTGCCTTTCATATCACTAAGAGATTATCTGATGAT; GATCGTGTGATATGGGCTGAACAACAGTATGAAAAAGAAAGAAGTAAACGTTCAGCTCTAAGGGACTCA; GCACTAAATCTCTTCAATGATCCCATGTGGAATCAGCAATGGTACTTGCAAGATACCAGGATGACGGCA; GCCCTGCCCAAGCTGGACCTTCATGTGATACCTGTTTGGCAAAAAGGCATTACGGGCAAAGGAGTTGTT; ATCACCGTACTGGATGATGGTTTGGAGTGGAATCACACGGACATTTATGCCAACTATGATCCAGAGGCT; AGCTATGATTTTAATGATAATGACCATGATCCATTTCCCCGATATGATCCCACAAACGAGAACAAACAC; GGGACCAGATGTGCAGGAGAAATTGCCATGCAAGCAAATAATCACAAATGCGGGGTTGGAGTTGCATAC; AATTCCAAAGTTGGAGGCATAAGAATGCTGGATGGCATTGTGACGGATGCTATTGAGGCCAGTTCAATT; GGATTCAATCCTGGACACGTGGATATTTACAGTGCAAGCTGGGGCCCTAATGATGATGGGAAAACTGTG; GAGGGGCCTGGCCGGCTAGCCCAGAAGGCTTTTGAATATGGTGTCAAACAGGGGAGACAGGGGAAGGGG; TCCATCTTCGTCTGGGCTTCGGGAAACGGGGGGCGTCAGGGAGATAATTGTGACTGTGATGGCTACACA; GACAGCATCTACACCATCTCCATCAGCAGTGCCTCCCAGCAAGGCCTATCCCCCTGGTACGCTGAGAAG; TGCTCCTCCACACTGGCCACCTCTTACAGCAGCGGAGATTACACCGACCAGAGAATCACGAGCGCTGAC; CTGCACAATGACTGCACGGAGACGCACACAGGCACCTCGGCCTCTGCACCTCTGGCTGCTGGCATCTTC; GCTCTGGCCCTGGAAGCAAACCCAAATCTCACCTGGCGAGATATGCAGCACCTGGTTGTCTGGACCTCT; GAGTATGACCCGCTGGCCAATAACCCTGGATGGAAAAAGAATGGAGCAGGCTTGATGGTGAATAGTCGA; TTTGGATTTGGCTTGCTAAATGCCAAAGCTCTGGTGGATTTAGCTGACCCCAGGACCTGGAGGAGCGTG; CCTGAGAAGAAAGAGTGTGTTGTAAAGGACAATGACTTTGAGCCCAGAGCCCTGAAAGCTAATGGAGAA; GTTATCATTGAAATTCCAACAAGAGCTTGTGAAGGACAAGAAAATGCTATCAAGTCCCTGGAGCATGTA; CAATTTGAAGCAACAATTGAATATTCCCGAAGAGGAGACCTTCATGTCACACTTACTTCTGCTGCTGGA; ACTAGCACTGTGCTCTTGGCTGAAAGAGAACGGGATACATCTCCTAATGGCTTTAAGAATTGGGACTTC; ATGTCTGTTCACACATGGGGAGAGAACCCTATAGGTACTTGGACTTTGAGAATTACAGACATGTCTGGA; AGAATTCAAAATGAAGGAAGAATTGTGAACTGGAAGCTGATTTTGCACGGGACCTCTTCTCAGCCAGAG; CATATGAAGCAGCCTCGTGTGTACACGTCCTACAACACTGTTCAGAATGACAGAAGAGGGGTGGAGAAG; ATGGTGGATCCAGGGGAGGAGCAGCCCACACAAGAGAACCCTAAGGAGAACACCCTGGTGTCCAAAAGC; CCCAGCAGCAGCAGCGTAGGGGGCCGGAGGGATGAGTTGGAGGAGGGAGCCCCTTCCCAGGCCATGCTG; CGACTCCTGCAAAGTGCTTTCAGTAAAAACTCACCGCCAAAGCAATCACCAAAGAAGTCCCCAAGTGCA; AAGCTCAACATCCCTTATGAAAACTTCTACGAAGCCCTGGAAAAGCTGAACAAACCTTCCCAGCTTAAA; GACTCTGAAGACAGTCTGTATAATGACTATGTTGATGTTTTTTATAACACTAAACCTTACAAGCACAGA; GACGACCGGCTGCTTCAAGCTCTGGTGGACATTCTGAATGAGGAAAAT; ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT; TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC;
  Protein Sequence

  >Peptide sequence encoded by RC230447; Blue=ORF Red=Cloning site Green=Tag(s); ; MGKGSISFLFFSQIGSLENHYLFKHKNHPRRSRRSAFHITKRLSDDDRVIWAEQQYEKERSKRSALRDS; ALNLFNDPMWNQQWYLQDTRMTAALPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTDIYANYDPEA; SYDFNDNDHDPFPRYDPTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRMLDGIVTDAIEASSI; GFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGGRQGDNCDCDGYT; DSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDYTDQRITSADLHNDCTETHTGTSASAPLAAGIF; ALALEANPNLTWRDMQHLVVWTSEYDPLANNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRSV; PEKKECVVKDNDFEPRALKANGEVIIEIPTRACEGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAAG; TSTVLLAERERDTSPNGFKNWDFMSVHTWGENPIGTWTLRITDMSGRIQNEGRIVNWKLILHGTSSQPE; HMKQPRVYTSYNTVQNDRRGVEKMVDPGEEQPTQENPKENTLVSKSPSSSSVGGRRDELEEGAPSQAML; RLLQSAFSKNSPPKQSPKKSPSAKLNIPYENFYEALEKLNKPSQLKDSEDSLYNDYVDVFYNTKPYKHR; DDRLLQALVDILNEEN; TRTRPLEQKLISEEDLAANDILDYKDDDDKV;
• Species: Human
• Serotype: AAV-2
• ACCN: NM_001177875
• ORF Size: 2118 bp
• Buffer: PBS with 0.001% Pluronic F9800
• Stability: AAV is stable for 1 year when stored at -80°C (long-term storage) or 2-3 weeks when stored at -20°C (short-term storage). Thaw the vial of AAV on ice prior to use and keep it on ice during the experiment. Thawed AAV can be stored at 4°C for 1-2 weeks. Whenever possible, particles should be aliquoted into single use portions to avoid repeated freeze/thaw cycles. Please aliquot at least 10ul per tube and use low protein binding tubes to avoid loss of virus.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_001177875.2
• RefSeq Size: 4828 bp
• RefSeq ORF: 2121 bp
• Locus ID: 5122
• UniProt ID: P29120
• Cytogenetics: 5q15
• MW: 79 kDa