CD163 (NM_004244) Human 3' UTR Clone

SKU SC208301

3' UTR clone of CD163 molecule (CD163) transcript variant 1 for miRNA target validation

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Target Symbol: CD163
• Synonyms: M130; MM130; SCARI1
• ACCN: NM_004244
• Insert Size: 626 bp
• Sequence Data:
  Insert Sequence

  >SC208301 3’UTR clone of NM_004244 ; The sequence shown below is from the reference sequence of NM_004244. The complete sequence of this clone may contain minor differences, such as SNPs.; Blue=Stop Codon Red=Cloning site; ; GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG; TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC; CACACTGAAAAGGAAAATGGGAATTTATAACCCAGTGAGTTCAGCCTTTAAGATACCTTGATGAAGACC; TGGACTATTGAATGGAGCAGAAATTCACCTCTCTCACTGACTATTACAGTTGCATTTTTATGGAGTTCT; TCTTCTCCTAGGATTCCTAAGACTGCTGCTGAATTTATAAAAATTAAGTTTGTGAATGTGACTACTTAG; TGGTGTATATGAGACTTTCAAGGGAATTAAATAAATAAATAAGAATGTTATTGATTTGAGTTTGCTTTA; ATTACTTGTCCTTAATTCTATTAATTTCTAAATGGGCTTCCTAATTTTTTGTAGAGTTTCCTAGATGTA; TTATAATGTGTTTTATTTGACAGTGTTTCAATTTGCATATACAGTACTGTATATTTTTTCTTATTTGGT; TTGAATAATTTTCCTATTACCAAATAAAAATAAATTTATTTTTACTTTAGTTTTTCTAAGACAGGAAAA; GTTAATGATATTGAAGGGTCTGTAAATAATATATGGCTAACTTTATAAGGCATGACTCACAACGATTCT; TTAACTGCTTTTTGTTACTGTAATTCTGTTCACTAGAATAAAATGCAGAGCCACACCTGGTGAGGGCAC; AAAGA; ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA; CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG;
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
• Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_004244.6
• Locus ID: 9332
• Summary: The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]