Human B7-1 (CD80) ELISA Kit 1 x 96
$620.00
2 Weeks*
| Product Data | |
| Species | Human |
|---|---|
| Format | 8x12 divisible strips |
| Assay Type | Sandwich |
| Assay Length | 3.5 hours incubations; 0.5 hour washing and analyzing samples |
| Signal | Colorimetric |
| Curve Range | 0.313-20ng/ml |
| Sample Type | Human serum, plasma, and cell culture supernates. |
| Sample Volume | 100µl |
| Specificity | This kit is used for quantitative detection of CD80 |
| Sensitivity | 0.058ng/ml |
| Reactivity | Human |
| Cross Reactivity | There is no detectable cross-reactivity with other relevant proteins. |
| Interference | No significant interference observed with available related molecules. |
| Components |
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| Background | The Cluster of differentiation 80 (also CD80 and B7-1) is a B7, type I membrane protein in the immunoglobulin superfamily. CD80 is the ligand for the proteins CD28 (for autoregulation and intercellular association) and CTLA-4 on the surface of various immune cells, including B-cells, monocytes, or T-cells, but most typically at antigen-presenting cells (APCs) such as dendritic cells. Another ligand of CD80 is programmed death-ligand 1 (PD‐L1), expressed on the surface of T-cells, B-cells, DCs, and macrophages. This interaction is inhibiting and causes a reduction in T-cell activation as well as reduction of cytokine production. The up-regulation of CD80 has been linked to various autoimmune diseases, including multiple sclerosis, systemic lupus erythematosus and sepsis. CD80 is also linked to various cancers. |
| Gene Symbol | CD80 |
| Locus ID | 941 |
| Standard Curve |
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| Shipping | Blue Ice |
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| Datasheet | |
| Manual | |
| SDS | |
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.