Human CD19 ELISA Kit 1 x 96
$620.00
2 Weeks*
| Product Data | |
| Species | Human |
|---|---|
| Format | 8x12 divisible strips |
| Assay Type | Sandwich |
| Assay Length | 3.5 hours incubations; 0.5 hour washing and analyzing samples |
| Signal | Colorimetric |
| Curve Range | 62.5-4000pg/ml |
| Sample Type | Human serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. |
| Sample Volume | 100µl |
| Specificity | This kit is used for quantitative detection of CD19 |
| Sensitivity | 24pg/ml |
| Reactivity | Human |
| Cross Reactivity | There is no detectable cross-reactivity with other relevant proteins. |
| Interference | No significant interference observed with available related molecules. |
| Components |
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| Background | CD19 is a 95 kd Type I transmembrane glycoprotein that plays a central role in B cell activation and humoral immune responses. It is expressed in all B lineage cells, and is commonly used as a B cell lineage marker. CD19 is required for the responsiveness of mature B cell to antigen stimulation, germinal center development, and antibody affinity maturation. The CD19 protein associates with the B cell antigen receptor (BCR), CD81, CD38, CD21, CD22, and IFITM1/CD225/Leu13, which enables CD19 to amplify B cell signaling and reduce the threshold for antigen stimulation through the BCR. Dysregulation of CD19, can lead to the development of autoimmunity. CD19 has been implicated in autoimmune diseases, including rheumatoid arthritis and multiple sclerosis. CD19 has also been used to diagnose cancers that arise from this type of cell - notably B cell lymphomas, acute lymphoblastic leukemia (ALL), and chronic lymphocytic leukemia. |
| Gene Symbol | CD19 |
| Locus ID | 930 |
| Standard Curve |
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| Shipping | Blue Ice |
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| Datasheet | |
| Manual | |
| SDS | |
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.