Human CEACAM5 ELISA Kit 1 x 96
$600.00
2 Weeks*
| Product Data | |
| Species | Human |
|---|---|
| Format | 8x12 divisible strips |
| Assay Type | Sandwich |
| Assay Length | 3.5 hours incubations; 0.5 hour washing and analyzing samples |
| Signal | Colorimetric |
| Curve Range | 0.313-20ng/ml |
| Sample Type | Human serum, plasma, and other biological fluids. |
| Sample Volume | 100µl |
| Specificity | This kit is used for quantitative detection of CEACAM5 |
| Sensitivity | 99pg/ml |
| Reactivity | Human |
| Cross Reactivity | There is no detectable cross-reactivity with other relevant proteins. |
| Interference | No significant interference observed with available related molecules. |
| Components |
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| Background | Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) also known as CD66e (Cluster of Differentiation 66e), is a member of the carcinoembryonic antigen (CEA) gene family. CEACAM5 is often used as a synonym for cancer embryonic antigen (CEA). It is a well-known biomarker of many types of malignancies, such as colorectal cancer and non-small-cell lung cancer. Its primary function in the embryonic intestine and colon tumors is adhesion between epithelial cells. Also, it plays a significant role in the inhibition of differentiation and apoptosis in colon cells. There are evidences that high CEACAM5 expression is firmly associated with the CD133-positive colorectal cancer stem cells. High CEACAM5 expression has also been identified in ~25% of patients with advanced non-squamous non-small cell lung cancer (NSCLC) detectable via IHC (immunohistochemistry). Elevated levels of CEACAM5 in the serum of colorectal cancer (CRC) patients represent a clinical biomarker that correlates with disease recurrence. |
| Gene Symbol | CEACAM5 |
| Locus ID | 1048 |
| Standard Curve |
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| Shipping | Blue Ice |
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| Datasheet | |
| Manual | |
| SDS | |
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.