Mouse Gdnf ELISA KIT (1 x 96 wells)
SKU
EA102933
The Fast version of Picokine ELISA kits, assay takes less than 1.5 hours. Detect Mouse GDNF with <10pg/ml sensitivity. Format: 96-well plate with removable strips. Compatible samples: cell culture supernates, cell lysates, serum and plasma (heparin, EDTA). This is a TMB colorimetric sandwich ELISA kit with short assay time and fast experiment set up. GDNF tissue specificity: Expressed in both the central nervous system (CNS) and in non-CNS tissues. Expressed in a highly dynamic pattern in the anterior neuroectoderm during the early stages of neurogenesis between E7.5 and E10.5. Beginning at E10.5, expression begins in mesenchymal tissues of several organs including the digestive tract, kidney, testis, frontonasal mass, tooth primordium, tongue, mandible, whisker follicles, ear, eye, limb bud and in distinct regions of the brain. Also expressed in the heart, ileum, liver and muscle. .
$755.00
3 Weeks*
| Product Data | |
| Species | Mouse |
|---|---|
| Format | 8x12 divisible strips |
| Assay Type | Sandwich ELISA kit of Quantitative Detection for Mouse GDNF |
| Assay Length | 3.5 hours incubations; 1 hour washing and analyzing samples |
| Signal | Colorimetric |
| Curve Range | 31.2pg/ml-2000pg/ml |
| Specificity | This kit is used for quantitative detection of Mouse GDNF |
| Sensitivity | <10pg/ml |
| Reactivity | Mouse |
| Cross Reactivity | There is no detectable cross-reactivity with other relevant proteins. |
| Components |
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| Background | Glial cell line-derived neurotrophic factor(GDNF) is a glycosylated, disulfide-bonded homodimer that is a distantly related member of the transforming growth factor-beta superfamily.1 GDNF, is a potent neurotrophic factor that promotes the survival of dopaminergic neurones in cultures including embryonic neuronal cultures.2 GDNF, in addition to its potential role in the differentiation and survival of central nervous system neurons, has profound effects on kidney organogenesis and the development of the peripheral nervous system.3 GDNF may have utility in the treatment of Parkinson's disease, which is marked by progressive degeneration of midbrain dopaminergic neurons. |
| Gene Symbol | Gdnf |
| Locus ID | 14573 |
| Standard Curve |
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| Shipping | Blue Ice |
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| Datasheet | |
| SDS | |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.