Mouse Lgmn ELISA KIT (1 x 96 wells)
SKU
EA102402
For quantitative detection of mouse Legumain(total) in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).
$755.00
3 Weeks*
| Product Data | |
| Species | Mouse |
|---|---|
| Format | 8x12 divisible strips |
| Assay Type | Sandwich ELISA kit of Quantitative Detection for Mouse Legumain(total) |
| Assay Length | 3.5 hours incubations; 1 hour washing and analyzing samples |
| Signal | Colorimetric |
| Curve Range | 31.2pg/ml-2000pg/ml |
| Specificity | This kit is used for quantitative detection of Mouse Legumain(total) |
| Sensitivity | <10pg/ml |
| Reactivity | Mouse |
| Cross Reactivity | There is no detectable cross-reactivity with other relevant proteins. |
| Components |
|
| Background | Legumain (asparaginyl endopeptidase, citvac, proteinase B, hemoglobinase, PRSC1 gene product or LGMN (Homo sapiens), vicilin peptidohydrolase, bean endopeptidase) is an enzyme that in humans is encoded by the LGMN gene (previous symbolPRSC1). Using fluorescence in situ hybridization, the LGMN gene was mapped to chromosome 14q32.1. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. |
| Gene Symbol | Lgmn |
| Locus ID | 19141 |
| Shipping | Blue Ice |
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| Datasheet | |
| SDS | |
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.