mCherry Goat Polyclonal Antibody

SKU
AB0040-500
Goat Polyclonal Anti-mCherry Antibody
  $705.00
In Stock*
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Specifications
Specifications
Product Data
Application IF, WB
Recommended Dilution WB 1:500-1:5,000; IF 1:50-1:500; IHC (paraffin) 1:50-1:500; IHC (frozen) 1:50-1:500
Reactivity mCherry tag
Antibody Host Goat
Clonality Polyclonal
Immunogen Purified recombinant peptide produced in E. coli.
Isotype IgG
Formulation Polyclonal antibody supplied as a 500 µl (3 mg/ml) aliquot in PBS, 20% glycerol and 0.05% sodium azide.
Concentration 3mg/ml
Purification epitope affinity purified
Conjugation Unconjugated
Shipping Blue Ice
Background Red Fluorescent Protein
Note In 293HEK cells transfected with cds plasmid detects a band of 29 kDa by Western blot. This antibody (AB0040) recognizes very well tdTomato and does not recognize GFP (green fluorescent protein).
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Transplantation of wild-type mouse hematopoietic stem and progenitor cells ameliorates deficits in a mouse model of Friedreich's ataxia
Rocca, Goodman, Dulin et al
Sci Transl Med (2017) 9 (413) DOI: 10.1126/scitranslmed.aaj2347
Cited by 76
AI Summary: In this study, OriGene’s anti-FXN antibody (TA500522) was used to detect frataxin protein levels, contributing to the assessment of therapeutic efficacy following transplantation of wild-type hematopoietic stem and progenitor cells in a mouse model of Friedreich's ataxia.
FigureFigure
Tctex-1 controls ciliary resorption by regulating branched actin polymerization and endocytosis
Saito, Otsu, Hsu et al
EMBO Rep (2017) 18 (8), 1460-1472 DOI: 10.15252/embr.201744204
Cited by 57
AI Summary: In this study, OriGene products were used to facilitate gene knockdown and protein expression experiments, specifically utilizing OriGene's Tctex-1 shRNA (Cat# TL313345) and Tctex-1 Myc-DDK-tagged cDNA clone (Cat# RC209337) to investigate the role of Tctex-1 in ciliary resorption.
Excitation of GABAergic Neurons in the Bed Nucleus of the Stria Terminalis Triggers Immediate Transition from Non-Rapid Eye Movement Sleep to Wakefulness in Mice
Kodani, Soya, Sakurai
J Neurosci (2017) 37 (30), 7164-7176 DOI: 10.1523/JNEUROSCI.0245-17.2017
AI Summary: In this study, OriGene products including the mouse GAD67 cDNA clone (Cat# MR207316) and anti-GAD67 antibody (Cat# TA500486) were used to identify and characterize GABAergic neurons in the bed nucleus of the stria terminalis, facilitating the investigation of their role in sleep-wake transitions in mice.
Expression of mutant DISC1 in Purkinje cells increases their spontaneous activity and impairs cognitive and social behaviors in mice
Shevelkin, Terrillion, Abazyan et al
Neurobiol Dis (2017) 103, 144-153 DOI: 10.1016/j.nbd.2017.04.008
Cited by 22
AI Summary: OriGene products contributed to this study by providing the human DISC1 cDNA (OriGene, SC118099) used to generate the mutant DISC1 construct for expression in Purkinje cells.
FigureFigure
Human umbilical cord plasma proteins revitalize hippocampal function in aged mice
Castellano, Mosher, Abbey et al
Nature (2017) 544 (7651), 488-492 DOI: 10.1038/nature22067
Cited by 458
AI Summary: In this study, OriGene's anti-TIMP2 antibody (Cat# TA500494) was used to deplete TIMP2 from human cord plasma and to block TIMP2 function in brain slice experiments, enabling the authors to demonstrate the necessity of TIMP2 for the cognitive benefits and synaptic plasticity observed in aged mice treated with cord plasma.
FigureFigure
Transient Opening of the Mitochondrial Permeability Transition Pore Induces Microdomain Calcium Transients in Astrocyte Processes
Agarwal, Wu, Hughes et al
Neuron (2017) 93 (3), 587-605.e7 DOI: 10.1016/j.neuron.2016.12.034
Cited by 473
AI Summary: In this study, OriGene's SOD1 G93A plasmid was used to express the ALS-associated mutant superoxide dismutase 1 in astrocytes, enabling the authors to investigate how this mutation enhances mitochondrial calcium transients and contributes to astrocyte dysfunction.
FigureFigure
Showing 1-6 of 12 papers.
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