Arginase 1 (ARG1) Mouse Monoclonal Antibody [Clone ID: UMAB288]

SKU UM870178

Arginase-1(ARG1) mouse monoclonal antibody, clone UMAB288

Product Data

• Clone Name: UMAB288
• Application: IHC, WB
• Recommended Dilution: WB 1:1000, IHC 1:15000
• Reactivity: Mouse, Rat
• Antibody Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human ARG1 (NP_000036) produced in HEK293T cell.
• Buffer: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Shipping: Blue Ice
• Predicted Protein Size: 34.7 kDa
• Gene Name: arginase 1
• Database Link:
  NP_000036
  P05089
• Background: Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Arginine and proline metabolism, Metabolic pathways