PARN Mouse Monoclonal Antibody [Clone ID: UMAB143]
SKU
UM870040
PARN mouse monoclonal antibody,clone UMAB143
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UltraMAB®
Mono-reactivity verified using the high-density protein chip
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Product Data | |
Clone Name | UMAB143 |
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Application | 10k-ChIP, IHC, WB |
Recommended Dilution | WB 1:2000, IHC 1:100~200 |
Reactivity | Human, Mouse, Rat |
Antibody Host | Mouse |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 1-266 of human PARN (NP_002573) produced in E.coli. |
Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 0.5~1.0 mg/ml (Lot Dependent) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Blue Ice |
Gene Name | poly(A)-specific ribonuclease |
Database Link | |
Background | The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008] |
Synonyms | DAN |
Reference Data | |
Protein Families | Transcription Factors |
Protein Pathways | RNA degradation |
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Product Manuals |
FAQs |
SDS |
Antibody Resources |
SKU | Description | Size | Price | |
---|---|---|---|---|
UM800040 | PARN mouse monoclonal antibody,clone UMAB143 | 100 ul |
$610.00
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UM800040CF | Carrier-free (BSA/glycerol-free) PARN mouse monoclonal antibody,clone UMAB143 | 100 ug |
$657.00
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.