PARN Mouse Monoclonal Antibody [Clone ID: UMAB143]

SKU
UM870040
PARN mouse monoclonal antibody,clone UMAB143
  • UltraMAB®

    Mono-reactivity verified using the high-density protein chip

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$224.00
In Stock*
Specifications
Product Data
Clone Name UMAB143
Application 10k-ChIP, IHC, WB
Recommended Dilution WB 1:2000, IHC 1:100~200
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 1-266 of human PARN (NP_002573) produced in E.coli.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name poly(A)-specific ribonuclease
Database Link
Background The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Synonyms DAN
Reference Data
Protein Families Transcription Factors
Protein Pathways RNA degradation
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SKU Description Size Price
UM800040 PARN mouse monoclonal antibody,clone UMAB143 100 ul
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Citations

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