PD1 (PDCD1) Mouse Monoclonal Antibody [Clone ID: UMAB199]

CAT#: UM800091CF

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Carrier-free (BSA/glycerol-free) PD-1 (PDCD1) mouse monoclonal antibody,clone UMAB199

Formulation: Standard Carrier-Free



USD 657.00

In Stock*

Size
    • 100 ug

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Specifications

Product Data
Clone Name UMAB199
Applications 10k-ChIP, IF, IHC, WB
Recommended Dilution IHC 1:1000, WB 1:500, IF 1:100
Reactivities Human, Mouse, Dog, Rat
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Full length human recombinant protein of human PDCD1 (NP_005009) produced in HEK293T cell.
Formulation Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 29.2 kDa
Gene Name Homo sapiens programmed cell death 1 (PDCD1), mRNA.
Background This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul
Synonyms CD279; hPD-1; hPD-l; hSLE1; PD-1; PD1; SLEB2
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cell adhesion molecules (CAMs), T cell receptor signaling pathway
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.