Gemin 8 (GEMIN8) Mouse Monoclonal Antibody [Clone ID: UMAB185]

SKU UM800077CF

Carrier-free (BSA/glycerol-free) GEMIN8 mouse monoclonal antibody,clone UMAB185

Product Data

• Clone Name: UMAB185
• Application: 10k-ChIP, IHC, WB
• Recommended Dilution: IHC 1:100~400
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human GEMIN8 (NP_060326) produced in E.coli.
• Buffer: Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
• Reconstitution Method: For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Ambient
• Predicted Protein Size: 28.5 kDa
• Gene Name: gem nuclear organelle associated protein 8
• Database Link:
  NP_060326
  Q9NWZ8
• Background: The protein encoded by this gene is part of the SMN complex, which is necessary for spliceosomal snRNP assembly in the cytoplasm and pre-mRNA splicing in the nucleus. The encoded protein binds to both SMN1 and the GEMIN6/GEMIN7 heterodimer, mediating their interaction. This protein is found in nuclear Gemini of Cajal bodies (gems) and in the cytoplasm. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010]
• Synonyms: FAM51A1

Reference Data