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ERCC1 Mouse Monoclonal Antibody [Clone ID: 4F9]

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SKU
UM570008
Anti-ERCC1 mouse monoclonal antibody, clone 4F9
Size:
30 ul 100 ul
Conjugation:
Unconjugated
  $224.00
In Stock*
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View other "ERCC1 or NM_001983" antibodies

Specifications
Specifications
Product Data
Clone Name 4F9
Application 10k-ChIP, IF, IHC, Simple Western, WB
Recommended Dilution WB 1:2000, IHC 1:50, IF 1:100 ; Simple Western 1:20-1:50
Reactivity Human, Mouse
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Protein expressed in 293T cell transfected with human ERCC1 expression vector
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 32.6 kDa
Gene Name ERCC excision repair 1, endonuclease non-catalytic subunit
Database Link
Background The product of this gene functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4), and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion. The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks. Mutations in this gene result in cerebrooculofacioskeletal syndrome, and polymorphisms that alter expression of this gene may play a role in carcinogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. The last exon of this gene overlaps with the CD3e molecule, epsilon associated protein gene on the opposite strand.
Synonyms COFS4; RAD10; UV20
Reference Data
Protein Categories Growth Factors, Intracellular Proteins
Protein Families Druggable Genome
Protein Pathways Nucleotide excision repair
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Other "4F9" antibodies (2)
SKU Description Size Price
UM500008 Anti-ERCC1 mouse monoclonal antibody, clone 4F9 100 ul
$610.00
UM500008CF Carrier-free (BSA/glycerol-free) anti-ERCC1 mouse monoclonal antibody, clone 4F9 100 ug
$680.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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