ALDH1L1 Mouse Monoclonal Antibody [Clone ID: UMAB44]
SKU
UM500040CF
Carrier-free (BSA/glycerol-free) ALDH1L1 mouse monoclonal antibody, clone UMAB44
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UltraMAB®
Mono-reactivity verified using the high-density protein chip
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Product Data | |
Clone Name | UMAB44 |
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Application | IF, IHC, WB |
Recommended Dilution | IHC 1:100, IF 1:100 |
Reactivity | Dog, Human, Mouse, Rat |
Antibody Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human ALDH1L1 (NP_036322) produced in HEK293T cell. |
Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 98.6 kDa |
Gene Name | aldehyde dehydrogenase 1 family member L1 |
Database Link | |
Background | The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012] |
Synonyms | 10-fTHF; 10-FTHFDH; FDH; FTHFD |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | One carbon pool by folate |
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