ALDH1L1 Mouse Monoclonal Antibody [Clone ID: UMAB43]

CAT#: UM500039CF

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Carrier-free (BSA/glycerol-free) ALDH1L1 mouse monoclonal antibody, clone UMAB43

Formulation: Standard Carrier-Free



  View other "UMAB43" antibodies (2)

USD 657.00

In Stock*

Size
    • 100 ug

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Specifications

Product Data
Clone Name UMAB43
Applications IF, IHC, WB
Recommended Dilution WB 1:500, IHC 1:400, IF 1:100
Reactivities Human, Mouse, Rat, Monkey, Dog
Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Full length human recombinant protein of human ALDH1L1 (NP_036322) produced in HEK293T cell.
Formulation Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 98.6 kDa
Gene Name Homo sapiens aldehyde dehydrogenase 1 family member L1 (ALDH1L1), transcript variant 2, mRNA.
Background The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]
Synonyms 10-fTHF; 10-FTHFDH; FDH; FTHFD
Reference Data
Protein Families Druggable Genome
Protein Pathways One carbon pool by folate

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