beta Catenin (CTNNB1) Mouse Monoclonal Antibody [Clone ID: UMAB15]

CAT#: UM500015

Beta-Catenin (CTNNB1) mouse monoclonal antibody, clone UMAB15

Size: 30 ul 100 ul

Formulation: Standard Carrier-Free


  View other "UMAB15" antibodies (2)

Special Offer: Get a 15% discount on this product. Use code: "KO15".

USD 564.00

In Stock*

Size
    • 100 ul

Frequently bought together (3)
Transient overexpression lysate of catenin (cadherin-associated protein), beta 1, 88kDa (CTNNB1), transcript variant 1
    • 100 ug

USD 436.00


beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

USD 200.00


Recombinant protein of human catenin (cadherin-associated protein), beta 1, 88kDa (CTNNB1), 20 µg
    • 20 ug

USD 867.00

Other products for "beta Catenin"

Specifications

Product Data
Clone Name UMAB15
Applications 10k-ChIP, FC, IF, IHC, WB
Recommended Dilution WB 1:500, IHC 1:100, IF 1:100, FLOW 1:100
Reactivities Human, Mouse, Rat, Monkey
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human CTNNB1 (NP_001895) produced in HEK293T cell.
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 85.3 kDa
Gene Name catenin beta 1
Background The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.
Synonyms armadillo; CTNNB; MRD19
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transcription Factors
Protein Pathways Adherens junction, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Basal cell carcinoma, Colorectal cancer, Endometrial cancer, Focal adhesion, Leukocyte transendothelial migration, Melanogenesis, Pathogenic Escherichia coli infection, Pathways in cancer, Prostate cancer, Thyroid cancer, Tight junction, Wnt signaling pathway

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