TNFSF9 Mouse Monoclonal Antibody [Clone ID: OTI3B6]
Specifications
| Product Data | |
| Clone Name | OTI3B6 |
|---|---|
| Application | FC, WB |
| Recommended Dilution | WB 1:1000, FLOW 1:100 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human CD137L (NP_003802) produced in HEK293T cell. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 26.4 kDa |
| Gene Name | tumor necrosis factor superfamily member 9 |
| Database Link | |
| Background | The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction. provided by RefSeq, Oct 2008 |
| Synonyms | 4-1BB-L; CD137L; TNLG5A |
| Reference Data | |
| Protein Categories | Cytokines, Intracellular Proteins |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Cytokine-cytokine receptor interaction |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI3B6" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF813213 | Carrier-free (BSA/glycerol-free) CD137L mouse monoclonal antibody,clone OTI3B6 | 100 ug |
$620.00
|
|
| TA813213AM | CD137L mouse monoclonal antibody,clone OTI3B6, Biotinylated | 100 ul |
$509.00
|
|
| TA813213BM | CD137L mouse monoclonal antibody,clone OTI3B6, HRP conjugated | 100 ul |
$509.00
|
|
| TA813213S | CD137L mouse monoclonal antibody,clone OTI3B6 | 30 ul |
$200.00
|
|
Citations
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