TBLR1 (TBL1XR1) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI2A8]

SKU TA811698AM

TBL1XR1 mouse monoclonal antibody,clone OTI2A8, Biotinylated

Product Data

• Clone Name: OTI2A8
• Application: WB
• Recommended Dilution: WB 1:500~2000
• Reactivity: Human, Mouse, Rat
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human TBL1XR1 (NP_078941) produced in E.coli.
• Buffer: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Biotin
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 55.4 kDa
• Gene Name: transducin (beta)-like 1 X-linked receptor 1
• Database Link:
  NP_078941
  Q9BZK7
• Background: This gene is a member of the WD40 repeat-containing gene family and shares sequence similarity with transducin (beta)-like 1X-linked (TBL1X). The protein encoded by this gene is thought to be a component of both nuclear receptor corepressor (N-CoR) and histone deacetylase 3 (HDAC 3) complexes, and is required for transcriptional activation by a variety of transcription factors. Mutations in these gene have been associated with some autism spectrum disorders, and one finding suggests that haploinsufficiency of this gene may be a cause of intellectual disability with dysmorphism. Mutations in this gene as well as recurrent translocations involving this gene have also been observed in some tumors. [provided by RefSeq, Mar 2016]
• Synonyms: C21; DC42; IRA1; MRD41; TBLR1

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Wnt signaling pathway