Cytochrome P450 26B (CYP26B1) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI4A8]

SKU TA811497BM

CYP26B1 mouse monoclonal antibody,clone OTI4A8, HRP conjugated

Product Data

• Clone Name: OTI4A8
• Application: WB
• Recommended Dilution: WB 1:2000
• Reactivity: Human, Mouse, Rat
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment corresponding to amino acids 229-512 of human CYP26B1 (NP_063938) produced in E.coli.
• Buffer: PBS (pH 7.3) containing 1% BSA, 50% glycerol.
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: HRP
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: cytochrome P450 family 26 subfamily B member 1
• Database Link:
  NP_063938
  Q9NR63
• Background: This gene encodes a member of the cytochrome P450 superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein is localized to the endoplasmic reticulum, and functions as a critical regulator of all-trans retinoic acid levels by the specific inactivation of all-trans retinoic acid to hydroxylated forms. Mutations in this gene are associated with radiohumeral fusions and other skeletal and craniofacial anomalies, and increased levels of the encoded protein are associated with atherosclerotic lesions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]
• Synonyms: CYP26A2; P450RAI-2; P450RAI2; RHFCA

Reference Data

• Protein Families: Druggable Genome, P450
• Protein Pathways: Retinol metabolism