GTP cyclohydrolase 1 (GCH1) Mouse Monoclonal Antibody [Clone ID: OTI5A1]

SKU
TA810265
GCH1 mouse monoclonal antibody,clone OTI5A1
  • TrueMAB

    Antibodies made against full-length proteins as antigens.

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$447.00
In Stock*
Specifications
Product Data
Clone Name OTI5A1
Application IHC, WB
Recommended Dilution WB 1:2000, IHC 1:500
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human GCH1 (NP_001019195) produced in E.coli.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 27.7 kDa
Gene Name GTP cyclohydrolase 1
Database Link
Background This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described; however, not all variants give rise to a functional enzyme. [provided by RefSeq, Jul 2008]
Synonyms DYT5; DYT5a; DYT14; GCH; GTP-CH-1; GTPCH1; HPABH4B
Reference Data
Protein Families Druggable Genome
Protein Pathways Folate biosynthesis, Metabolic pathways
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SKU Description Size Price
CF810265 Carrier-free (BSA/glycerol-free) GCH1 mouse monoclonal antibody,clone OTI5A1 100 ug
$600.00
TA810265AM GCH1 mouse monoclonal antibody,clone OTI5A1, Biotinylated 100 ul
$509.00
TA810265BM GCH1 mouse monoclonal antibody,clone OTI5A1, HRP conjugated 100 ul
$509.00
TA810265S GCH1 mouse monoclonal antibody,clone OTI5A1 30 ul
$200.00

Citations

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