TIMM8A Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI5C8]

SKU TA809738BM

TIMM8A mouse monoclonal antibody,clone OTI5C8, HRP conjugated

Product Data

• Clone Name: OTI5C8
• Application: IHC, WB
• Recommended Dilution: WB 1:500~2000, IHC 1:500
• Reactivity: Human, Mouse, Rat
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human TIMM8A (NP_004076) produced in E.coli.
• Buffer: PBS (pH 7.3) containing 1% BSA, 50% glycerol.
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: HRP
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: translocase of inner mitochondrial membrane 8 homolog A (yeast)
• Database Link:
  NP_004076
  O60220
• Background: This translocase is involved in the import and insertion of hydrophobic membrane proteins from the cytoplasm into the mitochondrial inner membrane. The gene is mutated in Mohr-Tranebjaerg syndrome/Deafness Dystonia Syndrome (MTS/DDS) and it is postulated that MTS/DDS is a mitochondrial disease caused by a defective mitochondrial protein import system. Defects in this gene also cause Jensen syndrome; an X-linked disease with opticoacoustic nerve atrophy and muscle weakness. This protein, along with TIMM13, forms a 70 kDa heterohexamer. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2009]
• Synonyms: DDP; DDP1; DFN1; MTS; TIM8

Reference Data

• Protein Families: Druggable Genome