BNP (NPPB) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI11G4]

SKU TA809046AM

NPPB mouse monoclonal antibody, clone OTI11G4 (formerly 11G4), Biotinylated

Product Data

• Clone Name: OTI11G4
• Application: IHC, WB
• Recommended Dilution: WB 1:2000, IHC 1:150
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment corresponding to amino acids 27-102 of human NPPB (NP_002512) produced in E.coli.
• Buffer: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Biotin
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 11.9 kDa
• Gene Name: natriuretic peptide B
• Database Link:
  NP_002512
  P16860
• Background: This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq, Jul 2008]
• Synonyms: BNP; Iso-ANP

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Stem cell - Pluripotency