Islet 1 (ISL1) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI2D8]

SKU TA807585BM

ISL1 mouse monoclonal antibody, clone OTI2D8 (formerly 2D8), HRP conjugated

Product Data

• Clone Name: OTI2D8
• Application: WB
• Recommended Dilution: WB 1:500
• Reactivity: Human, Mouse, Rat
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment corresponding to amino acids 134-349 of human ISL1(NP_002193) produced in E.coli.
• Buffer: PBS (pH 7.3) containing 1% BSA, 50% glycerol.
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: HRP
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 38.9 kDa
• Gene Name: ISL LIM homeobox 1
• Database Link:
  NP_002193
  P61371
• Background: This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young. [provided by RefSeq, Jul 2008]
• Synonyms: Isl-1; ISLET1

Reference Data

• Protein Families: ES Cell Differentiation/IPS, Transcription Factors