Adrenomedullin (ADM) Mouse Monoclonal Antibody [Clone ID: OTI8A1]

SKU
TA806874S
ADM mouse monoclonal antibody, clone OTI8A1 (formerly 8A1)
  • TrueMAB

    Antibodies made against full-length proteins as antigens.

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$200.00
In Stock*
Specifications
Product Data
Clone Name OTI8A1
Application IHC
Recommended Dilution IHC 1:250
Reactivity Human
Antibody Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 22-146 of human ADM(NP_001115) produced in E.coli.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 20.2 kDa
Gene Name adrenomedullin
Database Link
Background Adrenomedullin, a hypotensive peptide found in human pheochromocytoma, consists of 52 amino acids, has 1 intramolecular disulfide bond, and shows a slight homology with the calcitonin gene-related peptide. It may function as a hormone in circulation control because it is found in blood in a considerable concentration. The precursor, called preproadrenomedullin, is 185 amino acids long. By RNA-blot analysis, human adrenomedullin mRNA was found to be highly expressed in several tissues. Genomic ADM DNA consists of 4 exons and 3 introns, with the 5-prime flanking region containing TATA, CAAT, and GC boxes. There are also multiple binding sites for activator protein-2 and a cAMP-regulated enhancer element. [provided by RefSeq, Jul 2008]
Synonyms AM; PAMP
Reference Data
Protein Families Druggable Genome, Secreted Protein
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Citations

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