P Glycoprotein (ABCB1) Mouse Monoclonal Antibody [Clone ID: OTI1A7]
$447.00
In Stock*
Specifications
| Product Data | |
| Clone Name | OTI1A7 |
|---|---|
| Application | IHC |
| Recommended Dilution | IHC 1:150 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 995-1280 of human ABCB1 (NP_000918) produced in SF9 cell. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | ATP binding cassette subfamily B member 1 |
| Database Link | |
| Background | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. provided by RefSeq, Jul 2008 |
| Synonyms | ABC20; CD243; CLCS; GP170; MDR1; p-170; P-GP; PGY1 |
| Reference Data | |
| Protein Categories | CD Markers, Immune system diseases, Intracellular Proteins, Membrane Proteins |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transmembrane |
| Protein Pathways | ABC transporters |
Reviews
Documents
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Resources
Other "OTI1A7" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF806702 | Carrier-free (BSA/glycerol-free) ABCB1 mouse monoclonal antibody, clone OTI1A7 (formerly 1A7) | 100 ug |
$620.00
|
|
| TA806702AM | ABCB1 mouse monoclonal antibody, clone OTI1A7 (formerly 1A7), Biotinylated | 100 ul |
$509.00
|
|
| TA806702BM | ABCB1 mouse monoclonal antibody, clone OTI1A7 (formerly 1A7), HRP conjugated | 100 ul |
$509.00
|
|
| TA806702S | ABCB1 mouse monoclonal antibody, clone OTI1A7 (formerly 1A7) | 30 ul |
$200.00
|
|
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in shipping.