Protein Z (PROZ) Mouse Monoclonal Antibody [Clone ID: OTI4F1]

SKU TA806675

PROZ mouse monoclonal antibody, clone OTI4F1 (formerly 4F1)

Product Data

• Clone Name: OTI4F1
• Application: IHC, WB
• Recommended Dilution: WB 1:2000, IHC 1:150
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment corresponding to amino acids 115-400 of human PROZ(NP_003882) produced in E.coli.
• Buffer: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 40.3 kDa
• Gene Name: protein Z, vitamin K dependent plasma glycoprotein
• Database Link:
  NP_003882
  P22891
• Background: This gene encodes a liver vitamin K-dependent glycoprotein that is synthesized in the liver and secreted into the plasma. The encoded protein plays a role in regulating blood coagulation by complexing with protein Z-dependent protease inhibitor to directly inhibit activated factor X at the phospholipid surface. Deficiencies in this protein are associated with an increased risk of ischemic arterial diseases and fetal loss. Mutations in this gene are the cause of protein Z deficiency. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan
• Synonyms: PZ

Reference Data

• Protein Families: Druggable Genome, Protease, Secreted Protein