NR0B2 Mouse Monoclonal Antibody [Clone ID: OTI7B5]
CAT#: TA806321S
NR0B2 mouse monoclonal antibody, clone OTI7B5 (formerly 7B5)
Size: 100 ul
View other "OTI7B5" antibodies (4)
Special Offer: Get his product for $99/€99. Use code: "Truesample".
USD 200.00
Specifications
Product Data | |
Clone Name | OTI7B5 |
Applications | IHC, WB |
Recommended Dilution | WB 1:2000 |
Reactivities | Human |
Host | Mouse |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human NR0B2 (NP_068804) produced in E.coli. |
Formulation | PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | nuclear receptor subfamily 0 group B member 2 |
Database Link | |
Background | The protein encoded by this gene is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. The gene product is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors, inhibiting their ligand-dependent transcriptional activation. In addition, interaction with estrogen receptors has been demonstrated, leading to inhibition of function. Studies suggest that the protein represses nuclear hormone receptor-mediated transactivation via two separate steps: competition with coactivators and the direct effects of its transcriptional repressor function. [provided by RefSeq, Jul 2008] |
Synonyms | SHP; SHP1 |
Reference Data | |
Protein Families | Druggable Genome, Transcription Factors |
Documents
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FAQs |
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Resources
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF806321 | Carrier-free (BSA/glycerol-free) NR0B2 mouse monoclonal antibody, clone OTI7B5 (formerly 7B5) |
USD 600.00 |
|
TA806321 | NR0B2 mouse monoclonal antibody, clone OTI7B5 (formerly 7B5) |
USD 447.00 |
|
TA806321AM | NR0B2 mouse monoclonal antibody, clone OTI7B5 (formerly 7B5), Biotinylated |
USD 509.00 |
|
TA806321BM | NR0B2 mouse monoclonal antibody, clone OTI7B5 (formerly 7B5), HRP conjugated |
USD 509.00 |
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