NR0B2 Mouse Monoclonal Antibody [Clone ID: OTI7B5]

SKU
TA806321
NR0B2 mouse monoclonal antibody, clone OTI7B5 (formerly 7B5)
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    Antibodies made against full-length proteins as antigens.

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$447.00
In Stock*
Specifications
Product Data
Clone Name OTI7B5
Application IHC, WB
Recommended Dilution WB 1:2000
Reactivity Human
Antibody Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Full length human recombinant protein of human NR0B2 (NP_068804) produced in E.coli.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name nuclear receptor subfamily 0 group B member 2
Database Link
Background The protein encoded by this gene is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. The gene product is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors, inhibiting their ligand-dependent transcriptional activation. In addition, interaction with estrogen receptors has been demonstrated, leading to inhibition of function. Studies suggest that the protein represses nuclear hormone receptor-mediated transactivation via two separate steps: competition with coactivators and the direct effects of its transcriptional repressor function. [provided by RefSeq, Jul 2008]
Synonyms SHP; SHP1
Reference Data
Protein Families Druggable Genome, Transcription Factors
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SKU Description Size Price
CF806321 Carrier-free (BSA/glycerol-free) NR0B2 mouse monoclonal antibody, clone OTI7B5 (formerly 7B5) 100 ug
$600.00
TA806321AM NR0B2 mouse monoclonal antibody, clone OTI7B5 (formerly 7B5), Biotinylated 100 ul
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TA806321BM NR0B2 mouse monoclonal antibody, clone OTI7B5 (formerly 7B5), HRP conjugated 100 ul
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TA806321S NR0B2 mouse monoclonal antibody, clone OTI7B5 (formerly 7B5) 30 ul
$200.00

Citations

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