BRIT1 (MCPH1) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI2A3]

SKU TA804914AM

MCPH1 mouse monoclonal antibody, clone OTI2A3 (formerly 2A3), Biotinylated

Product Data

• Clone Name: OTI2A3
• Application: IHC, WB
• Recommended Dilution: WB 1:2000, IHC 1:150
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment corresponding to amino acids 1-264 of human MCPH1 (NP_078872) produced in E.coli.
• Buffer: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Biotin
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 92.6 kDa
• Gene Name: microcephalin 1
• Database Link:
  NP_078872
  Q8NEM0
• Background: This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2010]
• Synonyms: BRIT1; MCT

Reference Data