GLI2 Mouse Monoclonal Antibody [Clone ID: OTI1F9]

SKU
TA804549
GLI2 mouse monoclonal antibody, clone OTI1F9 (formerly 1F9)
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$447.00
In Stock*
Specifications
Product Data
Clone Name OTI1F9
Application WB
Recommended Dilution WB 1:500
Reactivity Human
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 729-1123 of human GLI2 (NP_005261) produced in E.coli.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 167.6 kDa
Gene Name GLI family zinc finger 2
Database Link
Background This gene encodes a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B. [provided by RefSeq, Jul 2008]
Synonyms CJS; HPE9; PHS2; THP1; THP2
Reference Data
Protein Families Adult stem cells, Cancer stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS
Protein Pathways Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer
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SKU Description Size Price
CF804549 Carrier-free (BSA/glycerol-free) GLI2 mouse monoclonal antibody, clone OTI1F9 (formerly 1F9) 100 ug
$600.00
TA804549AM GLI2 mouse monoclonal antibody, clone OTI1F9 (formerly 1F9), Biotinylated 100 ul
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TA804549BM GLI2 mouse monoclonal antibody, clone OTI1F9 (formerly 1F9), HRP conjugated 100 ul
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TA804549S GLI2 mouse monoclonal antibody, clone OTI1F9 (formerly 1F9) 30 ul
$200.00

Citations

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