GBA Mouse Monoclonal Antibody [Clone ID: OTI4G4]

CAT#: TA803377

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GBA mouse monoclonal antibody, clone OTI4G4 (formerly 4G4)

Size: 30 ul 100 ul

Formulation: Standard Carrier-Free

Conjugation: Unconjugated Biotin HRP



  View other "OTI4G4" antibodies (4)

USD 447.00

In Stock*

Size
    • 100 ul

Frequently bought together (3)
Recombinant protein of human glucosidase, beta; acid (includes glucosylceramidase) (GBA), transcript variant 1
    • 100 ug

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Transient overexpression lysate of glucosidase, beta, acid (GBA), transcript variant 1
    • 100 ug

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beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

USD 200.00

Specifications

Product Data
Clone Name OTI4G4
Applications IHC, WB
Recommended Dilution WB 1:500, IHC 1:150
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 40-315 of human GBA (NP_000148) produced in E.coli.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 55.5 kDa
Gene Name glucosylceramidase beta
Background This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010]
Synonyms GBA1; GCB; GLUC
Reference Data
Protein Families Druggable Genome
Protein Pathways Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism

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